EC Number   |
Subunits |
Reference |
|---|
   2.4.1.198 | ? |
x * 40000, recombinant FLAG-tagged GntA, SDS-PAGE |
736199 |
| 2.4.1.198 | More |
GTP-bound Ras2 protein associates in vivo with enzyme complex and inhibits its activity |
658406 |
| 2.4.1.198 | More |
structure of enzyme complex, overview |
638134 |
| 2.4.1.198 | More |
the enzyme protein folds into a beta-sheet flanked by two alpha-helical domains |
759061 |
| 2.4.1.198 | More |
the six other components of glycosylphosphatidylinositol-N-acetylglucosaminyltransferase can form a complex without PIG-Y, but this complex does not have any detectable glycosylphosphatidylinositol-N-acetylglucosaminyltransferase activity. In PIG-A-deficient JY5 cells, PIG-Y is not coprecipitated with any other components. PIG-Y associates directly with PIG-A and indirectly with other components through the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase complex. Additionally, there is no detectable association between PIG-Y and any of Ras proteins |
675882 |
| 2.4.1.198 | More |
topological model of the enzyme complex |
638136 |
| 2.4.1.198 | tetramer |
analytical ultracentrifugation |
759061 |
