EC Number   |
Expression |
Reference |
|---|
   3.4.24.B4 | down |
17beta-estadiol reduces the MMP-13 promoter activity |
711282 |
| 3.4.24.B4 | down |
avocado/soybean unsaponifiables reduce the expression of MMP-13 in cartilage |
711042 |
| 3.4.24.B4 | down |
both the JNK inhibitor SP 600125 and PI-3K/Akt inhibitor LY 294002 can inhibit chloramphenicol-induced c-Jun phosphorylation, MMP-13 expression, and cell invasion |
713548 |
| 3.4.24.B4 | down |
doxycycline decreases MMP-13 expression in synoviocytes but not cartilage |
712837 |
| 3.4.24.B4 | down |
epigallocatechin-3-gallate, EGCG, from Camellia sinensis inhibits advanced glycation end product-induced expression of matrix metalloproteinase-13 in chondrocytes involving suppression of p38-MAPK and JNK activation, overview |
711043 |
| 3.4.24.B4 | down |
glucosamine-hydrochloride differentially downregulates COX-2 andMMP-13 expression in the interleukin-1beta-treated or phorpbol-12-myristate-13-acetate-treated skin fibroblasts via the p38 MAPK-independent COX-2 translational inhibition and the p38 MAPK-dependent MMP-13 transcriptional suppression, respectively |
712592 |
| 3.4.24.B4 | down |
HDAC4 represses MMP-13 transcription in osteoblastic cells, and parathyroid hormone controls this repression |
712498 |
| 3.4.24.B4 | down |
HDAC4 represses MMP-13 transcription in osteoblastic cells, and parathyroid hormone controls this repression. HDAC4 interacts with Runx2 on the RD site of the MMP-13 promoter. Binding of HDAC4 to Runx2 is decreased after PTH stimulation |
712498 |
| 3.4.24.B4 | down |
keratinocytes transfected with siRNA for MMP-13 exhibit downregulation of mRNA and protein expression of the MMP |
710806 |
| 3.4.24.B4 | down |
MMP-13-shRNA for 24 h significantly inhibits hypoxia-stimulated MMP-13 mRNA expression in cell lysate and enzyme activity in supernatant |
712559 |
