3.4.22.B66 | up |
O,O-diethyl-O-4-nitrophenylphosphate up-regulates caspase-12 expression in a dose-dependent manner, and pre-treatment with EGTA, heparin or procaine significantly inhibits O,O-diethyl-O-4-nitrophenylphosphate-induced increase of caspase-12 expression. During the application of 5 nM POX for 0-8 h, caspase-12 expression increases significantly and continuously, and reaches the peak after 8 h treatment. However, caspase-12 expression after treatment with 5 nM POX for 16 h is similar to the control |
718428 |