Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
EL-4 cell | - |
Mus musculus | - |
Organism | Comment | Expression |
---|---|---|
Mus musculus | O,O-diethyl-O-4-nitrophenylphosphate up-regulates caspase-12 expression in a dose-dependent manner, and pre-treatment with EGTA, heparin or procaine significantly inhibits O,O-diethyl-O-4-nitrophenylphosphate-induced increase of caspase-12 expression. During the application of 5 nM POX for 0-8 h, caspase-12 expression increases significantly and continuously, and reaches the peak after 8 h treatment. However, caspase-12 expression after treatment with 5 nM POX for 16 h is similar to the control | up |
General Information | Comment | Organism |
---|---|---|
physiological function | caspase-12 is an important upstream messenger in POX-induced apoptosis in EL-4 cells | Mus musculus |