EC Number |
Expression |
Reference |
---|
1.14.19.1 | down |
higher levels of stearoyl lysophosphatidylcholine and lower levels of oleoyl lysophosphatidylcholine in dextran sulfate sodium-treated mice compared to controls lead to the identification of dextran sulfate sodium-elicited inhibition of SCD1 expression in liver, Citrobacter rodentium-induced colitis and lipopolysaccharide treatment also suppresses SCD1 expression in liver |
697181 |
1.14.19.1 | down |
intracerebroventricular glucose administration strongly decreases hepatic Scd1 |
696445 |
1.14.19.1 | down |
mRNA level reduced in diabetic Zucker diabetic fatty islets |
713716 |
1.14.19.1 | more |
SCD-1 is not upregulated in HAEC cells upon palmitate treatment |
695468 |
1.14.19.1 | up |
C-reactive protein concentrations are positively associated with estimated SCD-1 activity |
697028 |
1.14.19.1 | up |
chronic food restriction and chronic food restriction/refeeding cause increased expression |
716200 |
1.14.19.1 | up |
dietary saturated fat strongly induces Scd1 expression |
696445 |
1.14.19.1 | up |
enzyme SCD1 is 28fold upregulated in enriched liver tumor-initiating cell populations and sporadically expressed in human hepatocellular carcinoma specimens, upregulation of SCD1 of self-renewing liver cancer cells in chemoresistant hepatospheres |
745482 |
1.14.19.1 | up |
hepatic SCD1 expression increases in experimental steatosis resulting from high fat diet and decreases in a methionine-choline-deficient dietary model of steatohepatitis resulting in the latter situation in significantly increased hepatic saturated fatty acid levels |
698977 |
1.14.19.1 | up |
isoform SCD-1 expression is dramatically induced in liver and heart in response to high-carbohydrate diet, SCD-1 expression is also induced by nuclear sterol regulatory element-binding protein-1 via the sterol regulatory element in its promoter, in aortic endothelial cells liver X receptor beta activation increases SCD-1 mRNA and protein expression |
695472 |