Literature summary for 1.14.19.1 extracted from

Chen, C.; Shah, Y.M.; Morimura, K.; Krausz, K.W.; Miyazaki, M.; Richardson, T.A.; Morgan, E.T.; Ntambi, J.M.; Idle, J.R.; Gonzalez, F.J.
Metabolomics reveals that hepatic stearoyl-CoA desaturase 1 downregulation exacerbates inflammation and acute colitis (2008), Cell Metab., 7, 135-147.

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Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
SCD1	-	Mus musculus
stearoyl-CoA desaturase 1	-	Mus musculus

Expression

Organism	Comment	Expression
Mus musculus	higher levels of stearoyl lysophosphatidylcholine and lower levels of oleoyl lysophosphatidylcholine in dextran sulfate sodium-treated mice compared to controls lead to the identification of dextran sulfate sodium-elicited inhibition of SCD1 expression in liver, Citrobacter rodentium-induced colitis and lipopolysaccharide treatment also suppresses SCD1 expression in liver	down

General Information

General Information	Comment	Organism
physiological function	Scd1 null mice are more susceptible to dextran sulfate sodium treatment than wild type mice, while oleic acid feeding and in vivo SCD1 rescue with SCD1 adenovirus alleviates the dextran sulfate sodium-induced phenotype	Mus musculus

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Release 2023.1 (January 2023)