Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adipose tissue | - |
Mus musculus | - |
liver | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
palmitoyl-CoA + NADH + H+ + O2 | - |
Mus musculus | palmitoleoyl-CoA + NAD+ + H2O | - |
? | |
stearoyl-CoA + NADH + H+ + O2 | - |
Mus musculus | oleoyl-CoA + NAD+ + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SCD1 | - |
Mus musculus |
stearoyl-CoA desaturase | - |
Mus musculus |
stearoyl-coenzyme A desaturase-1 | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | intracerebroventricular glucose administration strongly decreases hepatic Scd1 | down |
Mus musculus | dietary saturated fat strongly induces Scd1 expression | up |
General Information | Comment | Organism |
---|---|---|
physiological function | mice lacking Scd1 are protected from obesity and insulin resistance and are characterized by decreased fatty acid synthesis and increased fatty acid oxidation | Mus musculus |