EC Number |
Application |
Reference |
---|
2.5.1.21 | agriculture |
squalene synthase is an antifungal target |
-, 758735 |
2.5.1.21 | drug development |
enzyme SQS is a potential target for antiviral strategies against hepatitis C virus |
738940 |
2.5.1.21 | drug development |
LdSSN is a potential drug target for visceral leishmaniasis |
-, 722293 |
2.5.1.21 | drug development |
the enzyme is a target for development of next-generation hypocholesterolemia drugs |
737480 |
2.5.1.21 | industry |
squalene has industrial value as a lubricant, health promoting agent, and/or drop-in biofuel, establishment of an efficient Escherichia coli-based system for squalene production |
738718 |
2.5.1.21 | medicine |
1-allyl-2-[3-(benzylamino)propoxy]-9H-carbazole shows 50% inhibition of enzyme at 63 nM, significant reduction of both plasma cholesterol and plasma triglyceride levels following oral dosing |
658266 |
2.5.1.21 | medicine |
aim of inhibitors in treatment of hypercholesterolemia |
697143 |
2.5.1.21 | medicine |
attractive target for pharmaceutical discovery in treatment of hypercholestermiae |
706801 |
2.5.1.21 | medicine |
enzyme may be important during response to infection and inflammation |
489856 |
2.5.1.21 | medicine |
induction of enzyme by a diet containing fluvastatin and cholestyramine |
489842 |