Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Reference on EC 3.6.5.3 - protein-synthesizing GTPase and Organism(s) Saccharolobus solfataricus and UniProt Accession Q980A5

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Raimo, G.; Masullo, M.; Lombardo, B.; Bocchini, V.
The archaeal elongation factor 1alpha bound to GTP forms a ternary complex with eubacterial and aukaryal aminoacyl-tRNA
Eur. J. Biochem.
267
6012-6017
2000
Saccharolobus solfataricus
Manually annotated by BRENDA team
Masullp, M.; De Vendittis, E.; Bocchini, V.
Archaebacterial elongation factor 1 alpha carries the catalytic site for GTP hydrolysis
J. Biol. Chem.
269
20376-20379
1994
Saccharolobus solfataricus
Manually annotated by BRENDA team
Masullo, M.; Cantiello, P.; de Paola, B.; Catanzano, F.; Arcari, P.; Bocchini, V.
G13A substitution affects the biochemical and physical properties of the elongation factor 1 alpha. A reduced intrinsic GTPase activity is partially restored by kirromycin
Biochemistry
41
628-633
2002
Saccharolobus solfataricus
Manually annotated by BRENDA team
Vitagliano, L.; Masullo, M.; Sica, F.; Zagari, A.; Bocchini, V.
The crystal structure of Sulfolobus solfataricus elongation factor 1alpha in complex with GDP reveals novel features in nucleotide binding and exchange
EMBO J.
20
5305-5311
2001
Saccharolobus solfataricus
Manually annotated by BRENDA team
Vitagliano, L.; Ruggiero, A.; Masullo, M.; Cantiello, P.; Arcari, P.; Zagari, A.
The crystal structure of Sulfolobus solfataricus elongation factor 1alpha in complex with magnesium and GDP
Biochemistry
43
6630-6636
2004
Saccharolobus solfataricus
Manually annotated by BRENDA team
Tanfani, F.; Scire, A.; Masullo, M.; Raimo, G.; Bertoli, E.; Bocchini, V.
Salts induce structural changes in elongation factor 1alpha from the hyperthermophilic archaeon Sulfolobus solfataricus: a Fourier transform infrared spectroscopic study
Biochemistry
40
13143-13148
2001
Saccharolobus solfataricus
Manually annotated by BRENDA team
Granata, V.; Graziano, G.; Ruggiero, A.; Raimo, G.; Masullo, M.; Arcari, P.; Vitagliano, L.; Zagari, A.
Chemical denaturation of the elongation factor 1alpha isolated from the hyperthermophilic archaeon Sulfolobus solfataricus
Biochemistry
45
719-726
2006
Saccharolobus solfataricus
Manually annotated by BRENDA team
Masullo, M.; Ianniciello, G.; Arcari, P.; Bocchini, V.
Properties of truncated forms of the elongation factor 1alpha from the archaeon Sulfolobus solfataricus
Eur. J. Biochem.
243
468-473
1997
Saccharolobus solfataricus
Manually annotated by BRENDA team
De Vendittis, E.; Adinolfi, B.S.; Amatruda, M.R.; Raimo, G.; Masullo, M.; Bocchini, V.
The A26G replacement in the consensus sequence A-X-X-X-X-G-K-[T,S] of the guanine nucleotide binding site activates the intrinsic GTPase of the elongation factor 2 from the archaeon Sulfolobus solfataricus
Eur. J. Biochem.
262
600-605
1999
Saccharolobus solfataricus
Manually annotated by BRENDA team
Masullo, M.; Cantiello, P.; Arcari, P.
Archaeal elongation factor 1alpha from Sulfolobus solfataricus interacts with the eubacterial antibiotic GE2270A
Extremophiles
8
499-505
2004
Saccharolobus solfataricus
Manually annotated by BRENDA team
Masullo, M.; Cantiello, P.; Lamberti, A.; Longo, O.; Fiengo, A.; Arcari, P.
Cloning, expression and evolution of the gene encoding the elongation factor 1alpha from a low thermophilic Sulfolobus solfataricus strain
FEMS Microbiol. Lett.
218
285-290
2003
Saccharolobus solfataricus, Saccharolobus solfataricus (P35021)
Manually annotated by BRENDA team
Raimo, G.; Masullo, M.; Bocchini, V.
Studies on the polypeptide elongation factor 2 from Sulfolobus solfataricus. Interaction with guanosine nucleotides and GTPase activity stimulated by ribosomes
J. Biol. Chem.
270
21082-21085
1995
Saccharolobus solfataricus
Manually annotated by BRENDA team
Granata, V.; Graziano, G.; Ruggiero, A.; Raimo, G.; Masullo, M.; Arcari, P.; Vitagliano, L.; Zagari, A..
Stability against temperature of Sulfolobus solfataricus elongation factor 1alpha, a multi-domain protein
Biochim. Biophys. Acta
1784
573-581
2008
Saccharolobus solfataricus
Manually annotated by BRENDA team
Stolboushkina, E.; Nikonov, S.; Nikulin, A.; Blaesi, U.; Manstein, D.J.; Fedorov, R.; Garber, M.; Nikonov, O.
Crystal structure of the intact archaeal translation initiation factor 2 demonstrates very high conformational flexibility in the alpha- and beta-subunits
J. Mol. Biol.
382
680-691
2008
Saccharolobus solfataricus (Q980A5), Saccharolobus solfataricus
Manually annotated by BRENDA team
Ruggiero, I.; Cantiello, P.; Lamberti, A.; Sorrentino, A.; Martucci, N.M.; Ruggiero, A.; Arcone, R.; Vitagliano, L.; Arcari, P.; Masullo, M.
Biochemical characterisation of the D60A mutant of the elongation factor 1alpha from the archaeon Sulfolobus solfataricus
Biochimie
91
835-842
2009
Saccharolobus solfataricus
Manually annotated by BRENDA team
Satpati, P.; Simonson, T.
Conformational selection by the aIF2 GTPase: a molecular dynamics study of functional pathways
Biochemistry
51
353-361
2012
Saccharolobus solfataricus
Manually annotated by BRENDA team
Fischer, J.J.; Coatham, M.L.; Eagle Bear, S.; Brandon, H.E.; De Laurentiis, E.I.; Shields, M.J.; Wieden, H.J.
The ribosome modulates the structural dynamics of the conserved GTPase HflX and triggers tight nucleotide binding
Biochimie
94
1647-1659
2012
Saccharolobus solfataricus
Manually annotated by BRENDA team
Satpati, P.; Clavaguera, C.; Ohanessian, G.; Simonson, T.
Free energy simulations of a GTPase: GTP and GDP binding to archaeal initiation factor 2
J. Phys. Chem. B
115
6749-6763
2011
Saccharolobus solfataricus (Q980A5)
Manually annotated by BRENDA team
Raimo, G.; Masullo, M.; Scarano, G.; Bocchini, V.
The site for GTP hydrolysis on the archaeal elongation factor 2 is unmasked by aliphatic alcohols
Biochimie
78
832-837
1996
Saccharolobus solfataricus, Saccharolobus solfataricus ATCC 49255
Manually annotated by BRENDA team
de Vendittis, E.; Amatruda, M.R.; Raimo, G.; Bocchini, V.
Heterologous expression in Escherichia coli of the gene encoding an archaeal thermoacidophilic elongation factor 2. Properties of the recombinant protein
Biochimie
79
303-308
1997
Saccharolobus solfataricus
Manually annotated by BRENDA team
Martucci, N.M.; Lamberti, A.; Arcari, P.; Masullo, M.
The eubacterial protein synthesis inhibitor pulvomycin interacts with archaeal elongation factor 1alpha from Sulfolobus solfataricus
Biochimie
94
503-509
2012
Saccharolobus solfataricus
Manually annotated by BRENDA team
Lamberti, A.; Martucci, N.M.; Ruggiero, I.; Arcari, P.; Masullo, M.
Interaction between the antibiotic tetracycline and the elongation factor 1alpha from the archaeon Sulfolobus solfataricus
Chem. Biol. Drug Des.
78
260-268
2011
Saccharolobus solfataricus
Manually annotated by BRENDA team
Masullo, M.; Raimo, G.; Parente, A.; Gambacorta, A.; De Rosa, M.; Bocchini, V.
Properties of the elongation factor 1 alpha in the thermoacidophilic archaebacterium Sulfolobus solfataricus
Eur. J. Biochem.
199
529-537
1991
Saccharolobus solfataricus, Saccharolobus solfataricus MT-4 / DSM 5833
Manually annotated by BRENDA team
Martucci, N.M.; Lamberti, A.; Vitagliano, L.; Cantiello, P.; Ruggiero, I.; Arcari, P.; Masullo, M.
The magic spot ppGpp influences in vitro the molecular and functional properties of the elongation factor 1alpha from the archaeon Sulfolobus solfataricus
Extremophiles
16
743-749
2012
Saccharolobus solfataricus
Manually annotated by BRENDA team
Blombach, F.; Launay, H.; Zorraquino, V.; Swarts, D.C.; Cabrita, L.D.; Benelli, D.; Christodoulou, J.; Londei, P.; van der Oost, J.
An HflX-type GTPase from Sulfolobus solfataricus binds to the 50S ribosomal subunit in all nucleotide-bound states
J. Bacteriol.
193
2861-2867
2011
Saccharolobus solfataricus (Q980M3), Saccharolobus solfataricus P2 (Q980M3)
Manually annotated by BRENDA team
Huang, B.; Wu, H.; Hao, N.; Blombach, F.; van der Oost, J.; Li, X.; Zhang, X.C.; Rao, Z.
Functional study on GTP hydrolysis by the GTP-binding protein from Sulfolobus solfataricus, a member of the HflX family
J. Biochem.
148
103-113
2010
Saccharolobus solfataricus (Q980M3), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q980M3)
Manually annotated by BRENDA team
Maone, E.; Di Stefano, M.; Berardi, A.; Benelli, D.; Marzi, S.; La Teana, A.; Londei, P.
Functional analysis of the translation factor aIF2/5B in the thermophilic archaeon Sulfolobus solfataricus
Mol. Microbiol.
65
700-713
2007
Saccharolobus solfataricus
Manually annotated by BRENDA team
Schmitt, E.; Panvert, M.; Lazennec-Schurdevin, C.; Coureux, P.D.; Perez, J.; Thompson, A.; Mechulam, Y.
Structure of the ternary initiation complex aIF2-GDPNP-methionylated initiator tRNA
Nat. Struct. Mol. Biol.
19
450-454
2012
Saccharolobus solfataricus (Q97W59 and Q980A5 and Q97Z79), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q97W59 and Q980A5 and Q97Z79)
Manually annotated by BRENDA team
Wu, H.; Sun, L.; Blombach, F.; Brouns, S.J.; Snijders, A.P.; Lorenzen, K.; van den Heuvel, R.H.; Heck, A.J.; Fu, S.; Li, X.; Zhang, X.C.; Rao, Z.; van der Oost, J.
Structure of the ribosome associating GTPase HflX.
Proteins
78
705-713
2010
Saccharolobus solfataricus (Q980M3), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q980M3)
Manually annotated by BRENDA team
Bocchini, V.; Adinolfi, B.S.; Arcari, P.; Arcucci, A.; Dello Russo, A.; De Vendittis, E.; Ianniciello, G.; Masullo, M.; Raimo, G.
Protein engineering on enzymes of the peptide elongation cycle in Sulfolobus solfataricus
Biochimie
80
895-898
1998
Saccharolobus solfataricus (P30925), Saccharolobus solfataricus (P35021), Saccharolobus solfataricus (Q64214)
Manually annotated by BRENDA team
Dubiez, E.; Aleksandrov, A.; Lazennec-Schurdevin, C.; Mechulam, Y.; Schmitt, E.
Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2
Nucleic Acids Res.
43
2946-2957
2015
Saccharolobus solfataricus (Q980A5), Saccharolobus solfataricus P2 (Q980A5), Saccharolobus solfataricus JCM 11322 (Q980A5), Saccharolobus solfataricus ATCC 35092 (Q980A5), Saccharolobus solfataricus DSM 1617 (Q980A5)
Manually annotated by BRENDA team