Reference on EC 3.5.3.11 - agmatinase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Friedrich, B.; Magasanik, B.
Enzymes of agmatine degradation and the control of their synthesis in Klebsiella aerogenes
J. Bacteriol.
137
1127-1133
1979
Klebsiella aerogenes
Boldt, A.; Miersch, J.; Reinbothe, H.
Metabolism of agmatine in fruit-bodies of the fungus Panus tigrinus (bull. ex. fr.) sing.
Phytochemistry
10
731-738
1971
Lentinus tigrinus
-
Carvajal, N.; Olate, J.; Salas, M.; Lopez, V.; Cerpa, J.; Herrera, P.; Uribe, E.
Evidence that histidine-163 is critical for catalytic activity, but not for substrate binding to Escherichia coli agmatinase
Biochem. Biophys. Res. Commun.
264
196-200
1999
Escherichia coli
Vicente, C.; Legaz, M.E.
Purification and properties of agmatine amidinohydrolase of Evernia prunastri
Physiol. Plant.
55
335-339
1982
Evernia prunastri
-
Legaz, M.E.; Vicente, C.
Endogenous inactivators of arginase, L-arginine decarboxylase, and agmatine amidinohydrolase in Evernia prunastri thallus
Plant Physiol.
71
300-302
1983
Evernia prunastri
White Tabor, C.; Tabor, H.; Hafner, E.W.; Markham, G.D.; Boyle, S.M.
Cloning of the Escherichia coli genes for the biosynthetic enzymes fo polyamines
Methods Enzymol.
94
117-121
1983
Escherichia coli
Shaibe, E.; Metzer, E.; Halpern, Y.S.
Metabolic pathway for the utilization of L-arginine, L-ornithine, agmatine, and putrescine as nitrogen sources in Escherichia coli K-12
J. Bacteriol.
163
933-937
1985
Escherichia coli
Satishchandran, C.; Boyle S.M.
Purification and properties of agmatine ureohydrolase, a putrescine biosynthetic enzyme in Escherichia coli
J. Bacteriol.
165
843-848
1986
Escherichia coli
Sastre, M.; Regunathan, S.; Galea, E.; Reis, D.J.
Agmatinase activity in rat brain: a metabolic pathway for the degradation of agmatine
J. Neurochem.
67
1761-1765
1995
BRENDA: Rattus norvegicus
Textmining: Rattus
Szumanski, M.B.W.; Boyle, S.M.
Influence of cyclic AMP, agmatine and a novel protein encoded by a flanking gene on speB (agmatine ureohydrolase) in Escherichia coli
J. Bacteriol.
174
758-764
1992
Escherichia coli
Szumanski, M.B.W.; Boyle, S.M.
Analysis and sequence of the speB gene encoding agmatine ureohydrolase, a putrescine biosynthetic enzyme in Escherichia coli
J. Bacteriol.
172
538-547
1990
BRENDA: Escherichia coli
Textmining: Homo sapiens, Rattus, yeasts
Carvajal, N.; Lopez, V.; Salas, M.; Uribe, E.; Herrera, P.; Cerpa, J.
Manganese is essential for catalytic activity of Escherichia coli Agmatinase
Biochem. Biophys. Res. Commun.
258
808-811
1999
Escherichia coli
Wu, T.K.; Busby, R.W.; Houston, T.A.; McIlwaine, D.B.; Egan, L.A.; Townsend, C.A.
Identification, cloning, sequencing, and overexpression of the gene encoding proclavaminate amidino hydrolase and characterization of protein function in clavulanic acid biosynthesis
J. Bacteriol.
177
3714-3720
1995
Streptomyces clavuligerus, Transformation
Carvajal, N.; Orellana, M.S.; Salas, M.; Enriquez, P.; Alarcon, R.; Uribe, E.; Lopez, V.
Kinetic studies and site-directed mutagenesis of Escherichia coli agmatinase. A role for Glu274 in binding and correct positioning of the substrate guanidinium group
Arch. Biochem. Biophys.
430
185-190
2004
Escherichia coli
Salas, M.; Rodriguez, R.; Lopez, N.; Uribe, E.; Lopez, V.; Carvajal, N.
Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling
Eur. J. Biochem.
269
5522-5526
2002
Escherichia coli
Arakawa, N.; Igarashi, M.; Kazuoka, T.; Oikawa, T.; Soda, K.
D-arginase of Arthrobacter sp. KUJ 8602: characterization and its identity with Zn(2+)-guanidinobutyrase
J. Biochem.
133
33-42
2003
Escherichia coli, Rattus
Graham, D.E.; Xu, H.; White, R.H.
Methanococcus jannaschii uses a pyruvoyl-dependent arginine decarboxylase in polyamine biosynthesis
J. Biol. Chem.
277
23500-23507
2002
Chlamydia
Lee, J.A.; Ahn, H.J.; Ha, J.Y.; Shim, S.M.; Kim, K.H.; Kim, H.K.; Suh, S.W.
Crystallization and preliminary X-ray crystallographic analysis of a putative agmatinase from Deinococcus radiodurans
Acta Crystallogr. Sect. D
60
1890-1892
2004
BRENDA: Deinococcus radiodurans
Textmining: Escherichia coli, Homo sapiens, Mammalia
Kim, K.H.; Ahn, H.J.; Kim, D.J.; Lee, H.H.; Ha, J.Y.; Kim, H.K.; Yoon, H.J.; Suh, S.W.
Expression, crystallization and preliminary X-ray crystallographic analysis of human agmatinase
Acta Crystallogr. Sect. F
61
889-891
2005
BRENDA: Homo sapiens
Textmining: Escherichia coli
Goda, S.; Sakuraba, H.; Kawarabayasi, Y.; Ohshima, T.
The first archaeal agmatinase from anaerobic hyperthermophilic archaeon Pyrococcus horikoshii: cloning, expression, and characterization
Biochim. Biophys. Acta
1748
110-115
2005
BRENDA: Pyrococcus horikoshii
Textmining: archaeon, Bacteria, eukaryota, Escherichia coli
Dallmann, K.; Junker, H.; Balabanov, S.; Zimmermann, U.; Giebel, J.; Walther, R.
Human agmatinase is diminished in the clear cell type of renal cell carcinoma
Int. J. Cancer
108
342-347
2004
Homo sapiens
Ahn, H.J.; Kim, K.H.; Lee, J.; Ha, J.Y.; Lee, H.H.; Kim, D.; Yoon, H.J.; Kwon, A.R.; Suh, S.W.
Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily
J. Biol. Chem.
279
50505-50513
2004
BRENDA: Deinococcus radiodurans
Textmining: Homo sapiens, Mammalia
Salas, M.; Lopez, V.; Uribe, E.; Carvajal, N.
Studies on the interaction of Escherichia coli agmatinase with manganese ions: structural and kinetic studies of the H126N and H151N variants
J. Inorg. Biochem.
98
1032-1036
2004
BRENDA: Escherichia coli
Textmining: Dialysis
Jantaro, S.; Kidron, H.; Chesnel, D.; Incharoensakdi, A.; Mulo, P.; Salminen, T.; Maenpaa, P.
Structural modeling and environmental regulation of arginine decarboxylase in Synechocystis sp. PCC 6803
Arch. Microbiol.
184
397-406
2006
Synechocystis
Chen, H.; McCaig, B.C.; Melotto, M.; He, S.Y.; Howe, G.A.
Regulation of plant arginase by wounding, jasmonate, and the phytotoxin coronatine
J. Biol. Chem.
279
45998-46007
2004
plant, Bacteria, Fungi, vertebrata
Alarcon, R.; Orellana, M.S.; Neira, B.; Uribe, E.; Garcia, J.R.; Carvajal, N.
Mutational analysis of substrate recognition by human arginase type I -agmatinase activity of the N130D variant
FEBS J.
273
5625-5631
2006
Homo sapiens
Haenisch, B.; von Kuegelgen, I.; Boenisch, H.; Goethert, M.; Sauerbruch, T.; Schepke, M.; Marklein, G.; Hoefling, K.; Schroeder, D.; Molderings, G.J.
Regulatory mechanisms underlying agmatine homeostasis in humans
Am. J. Physiol. Gastrointest. Liver Physiol.
295
G1104-G1110
2008
Homo sapiens (Q9BSE5), Homo sapiens
North, M.L.; Khanna, N.; Marsden, P.A.; Grasemann, H.; Scott, J.A.
Functionally Important Role for Arginase 1 in the Airways Hyperresponsiveness of Asthma
Am. J. Physiol. Lung Cell Mol. Physiol.
296
L911-L920
2009
Homo sapiens, Homo sapiens (P05089), Mus musculus, Mus musculus (Q61176), Mus sp.
Bernstein, H.G.; Derst, C.; Stich, C.; Pruess, H.; Peters, D.; Krauss, M.; Bogerts, B.; Veh, R.W.; Laube, G.
The agmatine-degrading enzyme agmatinase: a key to agmatine signaling in rat and human brain?
Amino Acids
40
453-465
2010
BRENDA: Homo sapiens, Rattus norvegicus
Textmining: Rattus, Areas
Mella, C.; Martinez, F.; de Los Angeles Garcia, M.; Nualart, F.; Castro, V.; Bustos, P.; Carvajal, N.; Uribe, E.
Expression and localization of an agmatinase-like protein in the rat brain
Histochem. Cell Biol.
134
137-144
2010
BRENDA: Rattus norvegicus
Textmining: Rattus, Hippocampus, Metazoa, Mammalia
Chattopadhyay, M.K.; Tabor, C.W.; Tabor, H.
Polyamines are not required for aerobic growth of Escherichia coli: preparation of a strain with deletions in all of the genes for polyamine biosynthesis
J. Bacteriol.
191
5549-5552
2009
Escherichia coli
Madai, V.I.; Poller, W.C.; Peters, D.; Berger, J.; Paliege, K.; Bernard, R.; Veh, R.W.; Laube, G.
Synaptic localisation of agmatinase in rat cerebral cortex revealed by virtual pre-embedding
Amino Acids
43
1399-1403
2012
BRENDA: Rattus norvegicus
Textmining: Rattus, Electron
Ohnuma, M.; Terui, Y.; Tamakoshi, M.; Mitome, H.; Niitsu, M.; Samejima, K.; Kawashima, E.; Oshima, T.
N1-aminopropylagmatine, a new polyamine produced as a key intermediate in polyamine biosynthesis of an extreme thermophile, Thermus thermophilus
J. Biol. Chem.
280
30073-30082
2005
Thermus thermophilus (Q5SK28), Thermus thermophilus, Thermus thermophilus (Q5SJ85)
Bernstein, H.G.; Stich, C.; Jaeger, K.; Dobrowolny, H.; Wick, M.; Steiner, J.; Veh, R.; Bogerts, B.; Laube, G.
Agmatinase, an inactivator of the putative endogenous antidepressant agmatine, is strongly upregulated in hippocampal interneurons of subjects with mood disorders
Neuropharmacology
62
237-246
2012
Homo sapiens
Miller, D.; Xu, H.; White, R.H.
A new subfamily of agmatinases present in methanogenic Archaea is Fe(II) dependent
Biochemistry
51
3067-3078
2012
BRENDA: Methanocaldococcus jannaschii (Q57757), Methanocaldococcus jannaschii, Methanocaldococcus jannaschii DSM 2661 (Q57757)
Textmining: Archaea
Wang, X.; Ying, W.; Dunlap, K.A.; Lin, G.; Satterfield, M.C.; Burghardt, R.C.; Wu, G.; Bazer, F.W.
Arginine decarboxylase and agmatinase: an alternative pathway for de novo biosynthesis of polyamines for development of mammalian conceptuses
Biol. Reprod.
90
84
2014
BRENDA: Ovis aries (W5PHZ9)
Textmining: Mammalia
Burnat, M.; Flores, E.
Inactivation of agmatinase expressed in vegetative cells alters arginine catabolism and prevents diazotrophic growth in the heterocyst-forming cyanobacterium Anabaena
MicrobiologyOpen
3
777-792
2014
BRENDA: Anabaena sp. (Q8YUM9), Anabaena sp., Anabaena sp. PCC 7120 (Q8YUM9)
Textmining: Anabaena, cyanobacterium
Prunetti, L.; Graf, M.; Blaby, I.K.; Peil, L.; Makkay, A.M.; Starosta, A.L.; Papke, R.T.; Oshima, T., Wilson, D.N.; de Crécy-Lagard, V.
Deciphering the translation initiation factor 5A modification pathway in halophilic Archaea
Archaea
2016
7316725
2016
Haloferax volcanii (D4GWG4), Haloferax volcanii DSM 3757 (D4GWG4)
Lenis, Y.Y.; Elmetwally, M.A.; Tang, W.; Satterfield, C.; Dunlap, K.; Wu, G.; Bazer, F.W.
Functional roles of agmatinase during the peri-implantation period of pregnancy in sheep
Amino Acids
50
293-308
2018
Ovis aries (W5PHZ9), Ovis aries
Kumar, S.; Saragadam, T.; Punekar, N.S.
Novel route for agmatine catabolism in Aspergillus niger involves 4-guanidinobutyrase
Appl. Environ. Microbiol.
81
5593-5603
2015
Aspergillus niger, Aspergillus niger (W8R465)
Shao, Y.; Li, C.; Zhang, W.; Xu, W.; Duan, X.; Li, Y.; Qiu, Q.; Jin, C.
Cloning and comparative analysis the proximal promoter activities of arginase and agmatinase genes in Apostichopus japonicus
Dev. Comp. Immunol.
65
299-308
2016
Apostichopus japonicus (A0A146AXJ2), Apostichopus japonicus
Perez-Mozqueda, L.L.; Vazquez-Duhalt, R.; Castro-Longoria, E.
Role and dynamics of an agmatinase-like protein (AGM-1) in Neurospora crassa
Fungal Genet. Biol.
132
103264
2019
Neurospora crassa (Q1K7T0), Neurospora crassa
Quinones, M.; Cofre, J.; Benitez, J.; Garcia, D.; Romero, N.; Gonzalez, A.; Carvajal, N.; Garcia, M.; Lopez, V.; Schenk, G.; Uribe, E.
Insight on the interaction of an agmatinase-like protein with Mn(2+) activator ions
J. Inorg. Biochem.
145
65-69
2015
BRENDA: Rattus norvegicus
Textmining: Rattus, Ursidae
Cunningham-Rundles, S; Maas, WK
Isolation, characterization, and mapping of Escherichia coli mutants blocked in the synthesis of ornithine decarboxylase.
J Bacteriol
124
791-9
1975
Escherichia coli K-12
Panagiotidis, CA; Blackburn, S; Low, KB; Canellakis, ES
Biosynthesis of polyamines in ornithine decarboxylase, arginine decarboxylase, and agmatine ureohydrolase deletion mutants of Escherichia coli strain K-12.
Proc Natl Acad Sci U S A
84
4423-7
1987
Escherichia coli, Escherichia coli K-12
Shin, SM; Song, SH; Lee, JW; Kwak, MK; Kang, SO
Methylglyoxal synthase regulates cell elongation via alterations of cellular methylglyoxal and spermidine content in Bacillus subtilis.
Int J Biochem Cell Biol
91
14-28
2017
Bacillus subtilis
Müller, IB; Walter, RD; Wrenger, C
Structural metal dependency of the arginase from the human malaria parasite Plasmodium falciparum.
Biol Chem
386
117-26
2005
Plasmodium falciparum, Homo sapiens
Uribe, E; Salas, M; EnrÃquez, S; Orellana, MS; Carvajal, N
Cloning and functional expression of a rodent brain cDNA encoding a novel protein with agmatinase activity, but not belonging to the arginase family.
Arch Biochem Biophys
461
146-50
2007
Escherichia coli, Rattus, Rodentia
Khramov, VA
[Substrate for determination of agmatinase activity in bacteria]
Lab Delo
628-30
1977
Bacteria
Satishchandran, C; Boyle, SM
Antagonistic transcriptional regulation of the putrescine biosynthetic enzyme agmatine ureohydrolase by cyclic AMP and agmatine in Escherichia coli.
J Bacteriol
157
552-9
1984
Escherichia coli
Mistry, SK; Burwell, TJ; Chambers, RM; Rudolph-Owen, L; Spaltmann, F; Cook, WJ; Morris, SM
Cloning of human agmatinase. An alternate path for polyamine synthesis induced in liver by hepatitis B virus.
Am J Physiol Gastrointest Liver Physiol
282
G375-81
2002
Homo sapiens, Macacine alphaherpesvirus 1, Hepatitis B virus, Saccharomyces cerevisiae
Iyer, RK; Kim, HK; Tsoa, RW; Grody, WW; Cederbaum, SD
Cloning and characterization of human agmatinase.
Mol Genet Metab
75
209-18
2002
Homo sapiens, Escherichia coli, Mammalia
Shimotohno, KW; Hidaka, T; Morishita, T; Endo, T
Molecular cloning of the gene for edeine B1 amidinohydrolase in addition to the agmatinase activity in Bacillus subtilis.
Biol Pharm Bull
26
262-5
2003
Bacillus subtilis, Escherichia coli, Brevibacillus brevis
Inaba, Y; Tokishita, S; Hamada-Sato, N; Kobayashi, T; Imada, C; Yamagata, H; Watanabe, E
Development of agmatine sensor using the combination of putrescine oxidase and agmatinase for squid freshness.
Biosens Bioelectron
20
833-40
2004
Doryteuthis pealeii, Indicator
Castro, V; Fuentealba, P; Henríquez, A; Vallejos, A; Benítez, J; Lobos, M; Díaz, B; Carvajal, N; Uribe, E
Evidence for an inhibitory LIM domain in a rat brain agmatinase-like protein.
Arch Biochem Biophys
512
107-10
2011
Rattus
García, D; Ordenes, P; Benítez, J; González, A; García-Robles, MA; López, V; Carvajal, N; Uribe, E
Cloning of two LIMCH1 isoforms: characterization of their distribution in rat brain and their agmatinase activity.
Histochem Cell Biol
145
305-13
2016
Escherichia coli, Felis catus, Hippocampus, Rattus
Zamakhaev, M; Tsyganov, I; Nesterova, L; Akhova, A; Grigorov, A; Bespyatykh, J; Azhikina, T; Tkachenko, A; Shumkov, M
Mycolicibacterium smegmatis possesses operational agmatinase but contains no detectable polyamines.
Int J Mycobacteriol
9
138-143
0
Mycolicibacterium smegmatis
Reyes, MB; Martínez-Oyanedel, J; Navarrete, C; Mardones, E; Martínez, I; Salas, M; López, V; García-Robles, M; Tarifeño-Saldivia, E; Figueroa, M; García, D; Uribe, E
Insights into the Mn2+ Binding Site in the Agmatinase-Like Protein (ALP): A Critical Enzyme for the Regulation of Agmatine Levels in Mammals.
Int J Mol Sci
21
2020
Mammalia, Homo sapiens, Rodentia, Rattus
Chitrakar, I; Ahmed, SF; Torelli, AT; French, JB
Structure of the E. coli agmatinase, SPEB.
PLoS One
16
e0248991
2021
Escherichia coli, Electron
Maturana, P; Orellana, MS; Herrera, SM; Martínez, I; Figueroa, M; Martínez-Oyanedel, J; Castro-Fernandez, V; Uribe, E
Crystal Structure of Escherichia coli Agmatinase: Catalytic Mechanism and Residues Relevant for Substrate Specificity.
Int J Mol Sci
22
2021
Escherichia coli, Mammalia
Boyle, SM; Markham, GD; Hafner, EW; Wright, JM; Tabor, H; Tabor, CW
Expression of the cloned genes encoding the putrescine biosynthetic enzymes and methionine adenosyltransferase of Escherichia coli (speA, speB, speC and metK).
Gene
30
129-36
1984
Escherichia coli, plasmids, collection
Y?lmaz, E; ?ekero?lu, MR; Y?lmaz, E; Çokluk, E
Evaluation of plasma agmatine level and its metabolic pathway in patients with bipolar disorder during manic episode and remission period.
Int J Psychiatry Clin Pract
23
128-133
2019
Homo sapiens
Yamamoto, S; Nakao, H; Yamasaki, K; Takashina, K; Suemoto, Y; Shinoda, S
Activities and properties of putrescine-biosynthetic enzymes in Vibrio parahaemolyticus.
Microbiol Immunol
32
675-87
1988
Vibrio parahaemolyticus, Escherichia coli
Cataldi, AA; Algranati, ID
A probable new pathway for the biosynthesis of putrescine in Escherichia coli.
Biochem J
234
617-22
1986
Escherichia coli, Bacteria
Klein, RD; Geary, TG; Gibson, AS; Favreau, MA; Winterrowd, CA; Upton, SJ; Keithly, JS; Zhu, G; Malmberg, RL; Martinez, MP; Yarlett, N
Reconstitution of a bacterial/plant polyamine biosynthesis pathway in Saccharomyces cerevisiae.
Microbiology
145 ( Pt 2)
301-7
1999
Bacteria, Fungi, protozoa, Saccharomyces cerevisiae, Escherichia coli, plasmids, Avena sp., plant
Kotagale, NR; Taksande, BG; Gahane, AY; Ugale, RR; Chopde, CT
Repeated agmatine treatment attenuates nicotine sensitization in mice: modulation by alpha2-adrenoceptors.
Behav Brain Res
213
161-74
2010
Mus sp.
Umair, S; Patchett, ML; Bland, RJ; Simpson, HV
Arginine metabolism in the sheep abomasal nematode parasites Haemonchus contortus and Teladorsagia circumcincta.
Exp Parasitol
127
506-14
2011
Nematoda, Haemonchus contortus, Ovis aries, Teladorsagia circumcincta, Mammalia
Xu, D; Zhang, L
Metabolic engineering of Escherichia coli for agmatine production.
Eng Life Sci
19
13-20
2019
Escherichia coli
Sekula, B
The Neighboring Subunit Is Engaged to Stabilize the Substrate in the Active Site of Plant Arginases.
Front Plant Sci
11
987
2020
plant
Yamamoto, S; Yamasaki, K; Takashina, K; Katsu, T; Shinoda, S
Characterization of putrescine production in nongrowing Vibrio parahaemolyticus cells in response to external osmolality.
Microbiol Immunol
33
11-21
1989
Vibrio parahaemolyticus
Aricioglu-Kartal, F; Regunathan, S
Effect of chronic morphine treatment on the biosynthesis of agmatine in rat brain and other tissues.
Life Sci
71
1695-701
2002
Rattus
Dixit, MP; Rahmatkar, SN; Raut, P; Umekar, MJ; Taksande, BG; Kotagale, NR
Evidences for agmatine alterations in A?1-42induced memory impairment in mice.
Neurosci Lett
740
135447
2021
Hippocampus
Lee, BH; Kim, JM; Heo, SH; Mun, JH; Kim, J; Kim, JH; Jin, HY; Kim, GH; Choi, JH; Yoo, HW
Proteomic analysis of the hepatic tissue of Long-Evans Cinnamon (LEC) rats according to the natural course of Wilson disease.
Proteomics
2011
Rattus, Cinnamomum verum, animal
Yina, S; Chenghua, L; Weiwei, Z; Zhenhui, W; Zhimeng, L
The first description of complete invertebrate arginine metabolism pathways implies dose-dependent pathogen regulation in Apostichopus japonicus.
Sci Rep
6
23783
2016
Apostichopus japonicus, Escherichia coli, Vibrio, Vibrio parahaemolyticus, Vibrio splendidus
Schaefer, K; Wagener, J; Ames, RM; Christou, S; MacCallum, DM; Bates, S; Gow, NAR
Three Related Enzymes in Candida albicans Achieve Arginine- and Agmatine-Dependent Metabolism That Is Essential for Growth and Fungal Virulence.
mBio
11
2020
Candida albicans
Tricot, C; Piérard, A; Stalon, V
Comparative studies on the degradation of guanidino and ureido compounds by Pseudomonas.
J Gen Microbiol
136
2307-17
1990
Vogesella indigofera
Irie, T; Watarai, S; Kushi, Y; Kasama, T; Kodama, H
Analysis of gangliosides from carp intestinal mucosa.
Fish Shellfish Immunol
16
117-25
2004
Cyprinus carpio
Tsujimura, Y; Watarai, S; Uemura, A; Ohnishi, Y; Kodama, H
Effect of anti-ganglioside antibody in experimental Trypanosoma brucei infection in mice.
Res Vet Sci
78
245-7
2005
Mus sp.
Liang, HJ; Wei, W; Kang, XN; Guo, K; Cao, J; Su, JJ; Yang, C; Ou, C; Li, Y; Liu, YK
[Differentially expressed proteins in the precancerous stage of rat hepatocarcinogenesis induced by diethylnitrosamine.]
Zhonghua Gan Zang Bing Za Zhi
17
669-74
2009
Homo sapiens, Rattus
Haenisch, B; Bönisch, H; Cichon, S; Allam, JP; Novak, N; Molderings, GJ
Effects of exogenous agmatine in human leukemia HMC-1 and HL-60 cells on proliferation, polyamine metabolism and cell cycle.
Leuk Res
2011
Homo sapiens
Kitanaka, N; Kitanaka, J; Hall, FS; Uhl, GR; Watabe, K; Kubo, H; Takahashi, H; Tanaka, K; Nishiyama, N; Takemura, M
Agmatine attenuates methamphetamine-induced hyperlocomotion and stereotyped behavior in mice.
Behav Pharmacol
25
158-65
2014
Mus sp.
Meylan, EM; Breuillaud, L; Seredenina, T; Magistretti, PJ; Halfon, O; Luthi-Carter, R; Cardinaux, JR
Involvement of the agmatinergic system in the depressive-like phenotype of the Crtc1 knockout mouse model of depression.
Transl Psychiatry
6
e852
2016
Homo sapiens, Rodentia, Mus sp., Hippocampus
Kotagale, NR; Ali, MT; Chopde, CT; Umekar, MJ; Taksande, BG
Agmatine inhibits nicotine withdrawal induced cognitive deficits in inhibitory avoidance task in rats: Contribution of ?
Pharmacol Biochem Behav
167
42-49
2018
Metazoa
Weiss, T; Bernard, R; Bernstein, HG; Veh, RW; Laube, G
Agmatine modulates spontaneous activity in neurons of the rat medial habenular complex-a relevant mechanism in the pathophysiology and treatment of depression?
Transl Psychiatry
8
201
2018
Rattus, Homo sapiens, Areas
Wang, B; Xu, Y; Wang, X; Yuan, JS; Johnson, CH; Young, JD; Yu, J
A guanidine-degrading enzyme controls genomic stability of ethylene-producing cyanobacteria.
Nat Commun
12
5150
2021
Synechocystis sp.
Khramov, VA
[Inhibition of bacterial agmatinase by substrate analogs]
Vopr Med Khim
22
804-8
0
Proteus vulgaris
Khramov, VA
[Comparative study of bacterial agmatinase inhibition by derivatives of putrescine and aliphatic monoamines]
Biokhimiia
42
460-4
1977
Proteus vulgaris
Khramov, VA
[Inhibition of bacterial agmatinase by several aliphatic diamines]
Biokhimiia
41
553-6
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