Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
angiotensin II + H2O
hydrolyzed angiotensin II
Azoalbumin + H2O
?
-
-
-
?
Benzoyl-Gly-Gly-Lys + H2O
?
-
enzyme form FBA is much more active than FBB
-
-
?
benzoyl-L-arginine ethyl ester + H2O
?
-
artificial substrate
-
-
?
benzoyl-Phe-Val-Arg-4-methylcoumarin 7-amide + H2O
benzoyl-Phe-Val-Arg + 7-amino-4-methylcoumarin
-
convenient substrate for fruit bromelain, scarcely affected by stem bromelain
-
-
?
benzoyl-Phe-Val-Arg-p-nitroanilide + H2O
benzoyl-Phe-Val-Arg + p-nitroaniline
-
-
-
-
?
benzyl-Phe-Val-Arg-4-nitroanilide + H2O
benzyl-Phe-Val-Arg + 4-nitroaniline
preferred substrate of fruit bromelain
-
-
?
Benzyloxycarbonyl-Ala-Leu + H2O
Benzyloxycarbonyl-Ala + Leu
-
enzyme form FBA is much more active than FBB
-
-
?
benzyloxycarbonyl-Arg-Arg-4-nitroanilide + H2O
benzyloxycarbonyl-Arg-Arg + 4-nitroaniline
-
-
-
?
benzyloxycarbonyl-Arg-Arg-p-nitroanilide + H2O
benzyloxycarbonyl-Arg-Arg + p-nitroaniline
-
-
-
-
?
Benzyloxycarbonyl-Gly-Leu + H2O
Benzyloxycarbonyl-Gly + Leu
-
enzyme form FBA is much more active than FBB
-
-
?
Benzyloxycarbonyl-Gly-Phe + H2O
Benzyloxycarbonyl-Gly + Phe
-
-
-
-
?
Benzyloxycarbonyl-Gly-Tyr + H2O
Benzyloxycarbonyl-Gly + Tyr
-
-
-
-
?
Benzyloxycarbonyl-Gly-Val + H2O
Benzyloxycarbonyl-Gly + Val
-
enzyme form FBA is much more active than FBB
-
-
?
benzyloxyxarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O
?
-
-
-
?
bradykinin + H2O
fragments of bradykinin
bromelain + H2O
?
-
rapid self-digestion in aqueous solution, can be prevented by addition of alpha2-macroglobulin
-
?
Carbobenzoxy-Gly-Ala + H2O
Carbobenzoxy-Gly + Ala
-
enzyme form FBA is much more active than FBB
-
-
?
casein + H2O
hydrolyzed casein
-
-
-
-
?
casein + H2O
L-Tyr + ?
-
-
-
-
?
casein + H2O
tyrosine + ?
-
-
-
?
epsilon-NH2-Cap-Ala-Cys(S-Bzl)-7-amido-4-methylcoumarin + H2O
?
-
-
-
?
epsilon-NH2-Cap-Cys(S-Bzl)-Leu-7-amido-4-methylcoumarin + H2O
?
-
-
-
?
epsilon-NH2-Cap-Leu-Cys(S-Bzl)-7-amido-4-methylcoumarin + H2O
?
-
-
-
?
epsilon-NH2-Cap-Leu-Gly-7-amido-4-methylcoumarin + H2O
?
-
-
-
?
epsilon-NH2-Cap-Phe-Arg-7-amido-4-methylcoumarin + H2O
?
-
-
-
?
epsilon-NH2-Cap-Pro-Cys(S-Bzl)-7-amido-4-methylcoumarin + H2O
?
-
-
-
?
Hemoglobin + H2O
?
-
-
-
?
Hemoglobin + H2O
Hydrolyzed hemoglobin
-
-
-
-
?
Isolated soybean protein + H2O
Hydrolyzed soybean protein
-
-
-
-
?
N-alpha-benzoyl-DL-arginine-2-naphthylamide + H2O
N-alpha-benzoyl-DL-arginine + 2-naphthylamine
-
-
-
?
N-Benzoyl-L-Arg ethyl ester + H2O
N-Benzoyl-L-Arg + ethanol
-
-
-
-
?
N-benzoyl-L-tyrosine ethyl ester + H2O
?
-
artificial substrate
-
-
?
Nalpha-Benzoyl-Arg amide + H2O
Nalpha-Benzoyl-Arg + NH3
-
-
-
-
?
Nalpha-Benzoyl-DL-Arg 4-nitroanilide + H2O
Nalpha-Benzoyl-DL-Arg + 4-nitroaniline
-
-
-
-
?
Nalpha-benzoyl-L-arginine-4-nitroanilide + H2O
?
-
artificial substrate
-
-
?
protein + H2O
peptides
-
broad substrate specificity
-
?
sodium caseinate + H2O
?
-
-
-
?
Wheat gluten + H2O
Hydrolyzed wheat gluten
-
-
-
-
?
additional information
?
-
angiotensin II + H2O
hydrolyzed angiotensin II
-
cleavage between Tyr4-Ile5
cleavage between Tyr4-Ile5
?
angiotensin II + H2O
hydrolyzed angiotensin II
-
cleavage between Tyr4-Ile5
cleavage between Tyr4-Ile5
?
azocasein + H2O
?
-
-
-
-
?
azocasein + H2O
?
-
-
-
?
azocasein + H2O
?
-
-
-
-
?
bradykinin + H2O
fragments of bradykinin
-
cleavage between Gly4-Phe5 and Phe5-Ser6
cleavage between Gly4-Phe5 and Phe5-Ser6
?
bradykinin + H2O
fragments of bradykinin
-
cleavage between Gly4-Phe5 and Phe5-Ser6
cleavage between Gly4-Phe5 and Phe5-Ser6
?
casein + H2O
?
-
-
-
?
casein + H2O
?
-
enzyme is assayed using casein as a substrate with Coomassie dye to track completion of hydrolysis of casein, casein is hydrolysed to completion leading to a brown coloured solution, assay method development as a Bradford dye-binding-bromelain-casein system as an assay for heavy metals, based on colour development and its inhibition by Hg2+ and Cu2+
-
-
?
Fibrin + H2O
?
-
-
-
?
Fibrin + H2O
?
fibrinolytic activity in vivo
-
-
?
Gelatin + H2O
?
-
-
-
?
Gelatin + H2O
?
-
-
-
-
?
milk protein + H2O
?
-
about 62% hydrolysis
-
-
?
milk protein + H2O
?
-
about 69% hydrolysis
-
-
?
ovalbumin + H2O
?
-
about 50% hydrolysis
-
-
?
ovalbumin + H2O
?
-
about 66% hydrolysis
-
-
?
soybean protein + H2O
?
-
about 73% hydrolysis
-
-
?
soybean protein + H2O
?
-
about 82% hydrolysis
-
-
?
additional information
?
-
-
specificity overview
-
-
?
additional information
?
-
-
enzyme catalyzes synthesis of acylamino acid anilides
-
-
?
additional information
?
-
-
bromelain has a profound immunmodulatory effect, overview, bromelain affects blood coagulation, fibrinolysis, and platelet functions, mechanism, overview
-
?
additional information
?
-
-
enzyme is scarcely able to hydrolyze benzyloxycarbonyl-Arg-Arg-4-methylcoumarin 7-amide
-
-
?
additional information
?
-
-
bromelain is a cysteine protease containing a single thiol group in the active sites
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Asthma
Allergic reactions, including asthma, to the pineapple protease bromelain following occupational exposure.
Asthma
Asthma caused by bromelin inhalation.
Asthma
[Allergic bronchial asthma caused by bromelin]
Carcinoma, Hepatocellular
Cytotoxic Effect of Bromelain on HepG2 Hepatocellular Carcinoma Cell Line.
Colitis
Corrigendum: Inhibition of Epithelial TNF-? Receptors by Purified Fruit Bromelain Ameliorates Intestinal Inflammation and Barrier Dysfunction in Colitis.
Colitis
Inhibition of Epithelial TNF-? Receptors by Purified Fruit Bromelain Ameliorates Intestinal Inflammation and Barrier Dysfunction in Colitis.
Cough
Honey for acute cough in children.
COVID-19
Bromelain: A Review on its Potential as a Therapy for the Management of Covid-19.
Escherichia coli Infections
Proteolytic inhibition of Salmonella enterica serovar typhimurium-induced activation of the mitogen-activated protein kinases ERK and JNK in cultured human intestinal cells.
Hypersensitivity
[Allergic bronchial asthma caused by bromelin]
Infections
Benefit of dietary integrators for treating functional dyspepsia: a prospective pilot study.
Infections
Bromelain: A Review on its Potential as a Therapy for the Management of Covid-19.
Infections
Proteolytic inhibition of Salmonella enterica serovar typhimurium-induced activation of the mitogen-activated protein kinases ERK and JNK in cultured human intestinal cells.
Inflammatory Bowel Diseases
Bromelain treatment decreases neutrophil migration to sites of inflammation.
Influenza, Human
Structure of bromelain-released influenza virus haemagglutinin as revealed by electrophoresis, sedimentation and electron microscopy.
Influenza, Human
[Characteristics of isolating influenza virus hemagglutinin using purified bromelin]
Ischemic Stroke
The Alteration of Plasma Matrix Metalloproteinase-9 Level after the Addition of Bromelin 500 mg to Standard Therapy of Acute Ischemic Stroke and Its Correlation with Outcome.
Lung Neoplasms
Antimetastatic effect of bromelain with or without its proteolytic and anticoagulant activity.
Lymphoma
Germline V genes encode viable motheaten mouse autoantibodies against thymocytes and red blood cells.
Mastitis
[Clinical effect of ananase for stagnation mastitis]
Melanoma
Antitumor effects in vitro and in vivo and mechanisms of protection against melanoma B16F10-Nex2 cells by fastuosain, a cysteine proteinase from Bromelia fastuosa.
Neoplasm Metastasis
Antimetastatic effect of bromelain with or without its proteolytic and anticoagulant activity.
Neoplasm Metastasis
Antitumor effects in vitro and in vivo and mechanisms of protection against melanoma B16F10-Nex2 cells by fastuosain, a cysteine proteinase from Bromelia fastuosa.
Neoplasms
Antitumor effects in vitro and in vivo and mechanisms of protection against melanoma B16F10-Nex2 cells by fastuosain, a cysteine proteinase from Bromelia fastuosa.
Neoplasms
Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update.
Purpura, Thrombocytopenic, Idiopathic
Use of enzyme treatment to enhance reactivity of HLA and platelet-specific antibodies in solid-phase RBC adherence assays.
Rhinitis
Allergic reactions, including asthma, to the pineapple protease bromelain following occupational exposure.
Sinusitis
The use of Ananase in sinusitis. A study of 60 patients.
Sleep Initiation and Maintenance Disorders
Honey for acute cough in children.
Thrombosis
Thrombosis of the central retinal vein and its treatment with ananase.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
BROM1_ANACO
351
1
39055
Swiss-Prot
Secretory Pathway (Reliability: 1)
A0A2P6R6Y7_ROSCH
391
0
42860
TrEMBL
other Location (Reliability: 4)
A0A2P6PP88_ROSCH
358
1
41137
TrEMBL
Secretory Pathway (Reliability: 2)
A0A2P6Q4K4_ROSCH
347
0
38403
TrEMBL
Secretory Pathway (Reliability: 1)
Q4QDT6_LEIMA
774
0
86060
TrEMBL
other Location (Reliability: 2)
G7JXJ7_MEDTR
344
1
37932
TrEMBL
Secretory Pathway (Reliability: 1)
G7JDU9_MEDTR
340
0
37423
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2P6Q4S1_ROSCH
108
0
11874
TrEMBL
other Location (Reliability: 3)
A0A2P6S7H3_ROSCH
144
1
17068
TrEMBL
other Location (Reliability: 5)
A0A396H111_MEDTR
76
0
8395
TrEMBL
other Location (Reliability: 3)
A0A2P6RUJ8_ROSCH
341
1
37403
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2P6Q839_ROSCH
347
0
38540
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2P6Q841_ROSCH
121
1
14074
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2G9HMV4_9LAMI
291
0
32428
TrEMBL
Secretory Pathway (Reliability: 1)
Q4QCS9_LEIMA
976
0
107643
TrEMBL
other Location (Reliability: 1)
A0A396J8Q8_MEDTR
184
0
20690
TrEMBL
Secretory Pathway (Reliability: 2)
A0A2G9I775_9LAMI
311
0
34657
TrEMBL
other Location (Reliability: 3)
G7JCK2_MEDTR
345
1
37770
TrEMBL
Secretory Pathway (Reliability: 1)
G7L5S9_MEDTR
342
0
38370
TrEMBL
Secretory Pathway (Reliability: 2)
G7ITE7_MEDTR
341
1
37474
TrEMBL
Secretory Pathway (Reliability: 1)
A0A3S5H5A5_LEIDO
855
0
94799
TrEMBL
other Location (Reliability: 1)
A0A2P6Q4M5_ROSCH
339
1
37545
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2G9H6A9_9LAMI
341
0
36912
TrEMBL
Secretory Pathway (Reliability: 2)
A0A2G9FZL9_9LAMI
345
1
38653
TrEMBL
Secretory Pathway (Reliability: 1)
Q4Q3Y6_LEIMA
1379
0
150671
TrEMBL
other Location (Reliability: 2)
A0A396JHG6_MEDTR
352
0
39344
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2P6SGI4_ROSCH
340
0
37279
TrEMBL
Secretory Pathway (Reliability: 1)
G7ILI4_MEDTR
272
0
30579
TrEMBL
Secretory Pathway (Reliability: 3)
A0A3Q8IBS3_LEIDO
910
0
101334
TrEMBL
other Location (Reliability: 1)
A0A2P6RY18_ROSCH
144
0
15260
TrEMBL
other Location (Reliability: 2)
A0A2P6PTH1_ROSCH
340
0
37202
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2P6R110_ROSCH
241
0
26571
TrEMBL
other Location (Reliability: 5)
A0A2G9I0L0_9LAMI
341
0
37340
TrEMBL
Secretory Pathway (Reliability: 3)
A0A2G9HN36_9LAMI
310
0
34794
TrEMBL
other Location (Reliability: 5)
Q4QCS7_LEIMA
687
0
78274
TrEMBL
other Location (Reliability: 1)
A0A6G8J3M9_ANACO
352
1
38824
TrEMBL
Secretory Pathway (Reliability: 1)
Q6VN49_MEDTR
345
1
37747
TrEMBL
Secretory Pathway (Reliability: 1)
G7I6H4_MEDTR
267
0
28756
TrEMBL
Secretory Pathway (Reliability: 4)
A0A2P6Q4L9_ROSCH
377
0
42074
TrEMBL
Mitochondrion (Reliability: 4)
A0A2P6QB42_ROSCH
343
1
37874
TrEMBL
Secretory Pathway (Reliability: 1)
A0A6G8J4I0_ANACO
351
1
39026
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2G9I748_9LAMI
249
0
26988
TrEMBL
other Location (Reliability: 4)
I7J8U7_BABMR
Babesia microti (strain RI)
539
1
60375
TrEMBL
other Location (Reliability: 3)
A0A2P6RRY4_ROSCH
58
0
6156
TrEMBL
other Location (Reliability: 3)
A0A2G9I763_9LAMI
346
1
38733
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2G9HQ51_9LAMI
341
1
37548
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2P6Q4E9_ROSCH
356
0
40171
TrEMBL
Secretory Pathway (Reliability: 3)
A0A2P6QES1_ROSCH
149
0
15794
TrEMBL
other Location (Reliability: 2)
A0A2P6RUD4_ROSCH
150
0
15885
TrEMBL
other Location (Reliability: 2)
A0A2P6RY28_ROSCH
391
0
42708
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2P6QAQ3_ROSCH
317
0
34883
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2P6RY04_ROSCH
409
0
45454
TrEMBL
other Location (Reliability: 3)
A0A2P6PTH5_ROSCH
340
0
37162
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2G9HMS7_9LAMI
334
0
36617
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2G9I0M3_9LAMI
345
1
38365
TrEMBL
Secretory Pathway (Reliability: 1)
Q4Q9U3_LEIMA
705
0
80249
TrEMBL
other Location (Reliability: 2)
A0A2G9H6A2_9LAMI
341
0
36910
TrEMBL
Secretory Pathway (Reliability: 2)
G7J150_MEDTR
340
1
37273
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2P6Q4T5_ROSCH
83
0
8970
TrEMBL
other Location (Reliability: 5)
A0A2P6PRY4_ROSCH
317
0
36933
TrEMBL
other Location (Reliability: 3)
A0A2P6QJF1_ROSCH
341
0
38203
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2P6Q862_ROSCH
309
0
34636
TrEMBL
other Location (Reliability: 3)
A0A2P6Q4K6_ROSCH
345
0
38422
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2G9GNA4_9LAMI
338
0
37219
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2G9HMW7_9LAMI
341
0
37465
TrEMBL
Secretory Pathway (Reliability: 3)
A0A396JMT2_MEDTR
120
0
14181
TrEMBL
Secretory Pathway (Reliability: 1)
A0A3S7X6V3_LEIDO
1379
0
150271
TrEMBL
other Location (Reliability: 2)
A0A2P6RUK0_ROSCH
340
0
37200
TrEMBL
Secretory Pathway (Reliability: 1)
G7JPY3_MEDTR
345
1
37758
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2P6RCS9_ROSCH
348
0
38914
TrEMBL
Secretory Pathway (Reliability: 2)
A0A2P6RUK1_ROSCH
341
0
37418
TrEMBL
Secretory Pathway (Reliability: 3)
A0A2P6R6Z0_ROSCH
391
0
42805
TrEMBL
other Location (Reliability: 4)
A0A2P6RY32_ROSCH
96
0
10468
TrEMBL
Secretory Pathway (Reliability: 5)
A0A2G9H6A3_9LAMI
342
0
37219
TrEMBL
Secretory Pathway (Reliability: 1)
G7KQI7_MEDTR
340
0
38307
TrEMBL
Secretory Pathway (Reliability: 1)
A0A088RML9_9TRYP
758
0
84463
TrEMBL
other Location (Reliability: 2)
A0A3S7WW18_LEIDO
821
0
91542
TrEMBL
other Location (Reliability: 1)
A0A2P6RUL3_ROSCH
292
0
31794
TrEMBL
Mitochondrion (Reliability: 4)
A0A2P6RUE6_ROSCH
242
0
27220
TrEMBL
Secretory Pathway (Reliability: 1)
G7IM76_MEDTR
344
1
38524
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2G9I0N7_9LAMI
345
1
38186
TrEMBL
Secretory Pathway (Reliability: 1)
Q4QCS8_LEIMA
823
0
91358
TrEMBL
other Location (Reliability: 1)
A0A396H0Y3_MEDTR
157
0
17850
TrEMBL
Secretory Pathway (Reliability: 4)
G0QPD4_ICHMG
Ichthyophthirius multifiliis (strain G5)
360
2
42421
TrEMBL
other Location (Reliability: 2)
G7ILJ3_MEDTR
374
1
41971
TrEMBL
Secretory Pathway (Reliability: 1)
G7JVY2_MEDTR
343
1
37680
TrEMBL
Secretory Pathway (Reliability: 1)
G7I3S5_MEDTR
127
1
14788
TrEMBL
Secretory Pathway (Reliability: 4)
A0A2P6QB35_ROSCH
343
1
37798
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2P6RY24_ROSCH
125
0
13380
TrEMBL
other Location (Reliability: 2)
A0A396JMY0_MEDTR
161
0
17794
TrEMBL
Secretory Pathway (Reliability: 1)
G8A003_MEDTR
345
1
37726
TrEMBL
Secretory Pathway (Reliability: 1)
A0A088S1L0_9TRYP
856
0
94483
TrEMBL
other Location (Reliability: 1)
A0A2P6Q4L0_ROSCH
57
0
6625
TrEMBL
other Location (Reliability: 3)
A0A2G9I9F2_9LAMI
342
0
38108
TrEMBL
Secretory Pathway (Reliability: 2)
A0A6G8J3P8_ANACO
319
0
35472
TrEMBL
other Location (Reliability: 2)
A0A396JDR4_MEDTR
373
0
42021
TrEMBL
Secretory Pathway (Reliability: 1)
O23801_ANACO
324
0
36038
TrEMBL
-
O24641_ANACO
352
0
38823
TrEMBL
-
Q6Q2T4_9POAL
324
0
35745
TrEMBL
other Location (Reliability: 2)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Murachi, T.
Bromelain enzymes
Methods Enzymol.
19
273-284
1970
Ananas comosus
-
brenda
Murachi, T.
Bromelain enzymes
Methods Enzymol.
45
475-485
1976
Ananas comosus
brenda
Ota, S.; Horie, K.; Hagino, F.; Hashimoto, C.; Date, H.
Fractionation and some properties of the proteolytically active components of bromelains in the stem and the fruit of the pineapple plant
J. Biochem.
71
817-830
1972
Ananas comosus
brenda
Ota, S.; Muta, E.; Katahira, Y.; Okamoto, Y.
Reinvestigation of fractionation and some properties of the proteolytically active components of stem and fruit bromelains
J. Biochem.
98
219-228
1985
Ananas comosus
brenda
Rowan, A.D.; Brzin, J.; Buttle, D.J.; Barrett, A.J.
Inhibition of cysteine proteinases by a protein inhibitor from potato
FEBS Lett.
269
328-330
1990
Ananas comosus
brenda
Suh, H.J.; Lee, H.; Cho, H.Y.; Yang, H.C.
Purification and characterization of bromelain isolated from pineapple
Han'guk Nonghwa Hakhoechi
35
300-307
1992
Ananas comosus
-
brenda
Yamada, F.; Takahashi, N.; Murachi, T.
Purification and characterization of a proteinase from pineapple fruit, fruit bromelain FA2
J. Biochem.
79
1223-1234
1976
Ananas comosus
brenda
Sasaki, M.; Kato, T.; Iida, S.
Antigenic determinant common to four kinds of thiol proteases of plant origin
J. Biochem.
74
635-637
1973
Ananas comosus
brenda
Toro-Goyco, E.; Rodriguez-Costas, I.
Immunochemical studies on pinguinain. A sulfhydryl plant protease
Arch. Biochem. Biophys.
175
359-366
1976
Ananas comosus, Bromelia pinguin
brenda
Maurer, H.R.
Bromelain: biochemistry, pharmacology and medical use
Cell. Mol. Life Sci.
58
1234-1245
2001
Ananas comosus
brenda
Rowan, A.D.
Fruit bromelain
Handbook of proteolytic enzymes (Barrett, A. J. , Rawlings, N. D. , Woessner, J. F. , eds. ) Academic Press
2
1137-1138
2004
Ananas comosus
-
brenda
Hale, L.P.; Greer, P.K.; Trinh, C.T.; James, C.L.
Proteinase activity and stability of natural bromelain preparations
Int. Immunopharmacol.
5
783-793
2005
Ananas comosus
brenda
Hemavathi, A.B.; Hebbar, H.U.; Raghavarao, K.S.
Reverse micellar extraction of bromelain from Ananas comosus L. Merryl
J. Chem. Technol. Biotechnol.
82
985-992
2007
Ananas comosus (O23791)
-
brenda
Cabral, H.; Leopoldino, A.M.; Tajara, E.H.; Greene, L.J.; Faca, V.M.; Mateus, R.P.; Ceron, C.R.; de Souza Judice, W.A.; Julianod, L.; Bonilla-Rodriguez, G.O.
Preliminary functional characterization, cloning and primary sequence of Fastuosain, a cysteine peptidase isolated from fruits of Bromelia fastuosa
Protein Pept. Lett.
13
83-89
2006
Bromelia fastuosa (Q6Q2T4), Bromelia fastuosa
brenda
Shukor, M.Y.; Masdor, N.; Baharom, N.A.; Jamal, J.A.; Abdullah, M.P.; Shamaan, N.A.; Syed, M.A.
An inhibitive determination method for heavy metals using bromelain, a cysteine protease
Appl. Biochem. Biotechnol.
144
283-291
2008
Ananas comosus
brenda
Neuteboom, L.W.; Matsumoto, K.O.; Christopher, D.A.
An extended AE-rich N-terminal trunk in secreted pineapple cystatin enhances inhibition of fruit bromelain and is posttranslationally removed during ripening
Plant Physiol.
151
515-527
2009
Ananas comosus (O23791), Ananas comosus
brenda
Liang, H.; Li, M.; Shi, M.; Liao, A.; Wu, R.
Study on the stability of fruit bromelain
Adv. Mater. Res.
421
19-22
2012
Ananas comosus
-
brenda
Ferreira, J.; Bresolin, L.; Silveira, E.; Tambourgi, E.
Purification of bromelain from ananas comosus by PEG/phosphate ATPS
Chem. Eng. Transact.
24
931-936
2011
Ananas comosus
-
brenda
Yin, L.; Sun, C.; Han, X.; Xu, L.; Xu, Y.; Qi, Y.; Peng, J.
Preparative purification of bromelain (EC 3.4.22.33) from pineapple fruit by high-speed counter-current chromatography using a reverse-micelle solvent system
Food Chem.
129
925-932
2011
Ananas comosus
brenda
Gautam, S.; Mishra, S.; Dash, V.; Goyal, A.; Rath, G.
Comparative study of extraction, purification and estimation of bromelain from stem and fruit of pineapple plant
Thai J. Pharm. Sci.
34
67-76
2010
Ananas comosus
-
brenda
Arshad, Z.I.; Amid, A.; Yusof, F.; Jaswir, I.; Ahmad, K.; Loke, S.P.
Bromelain: an overview of industrial application and purification strategies
Appl. Microbiol. Biotechnol.
98
7283-7297
2014
Ananas comosus (O23791), Ananas comosus
brenda
Corzo, C.; Waliszewski, K.; Welti-Chanes, J.
Pineapple fruit bromelain affinity to different protein substrates
Food Chem.
133
631-635
2012
Ananas comosus (O23791)
brenda
Devi, Y.; Rupachandra Singh, L.; Kunjeshwori Devi, S.
Pineapple fruit bromelain and its application: A review
Indian J. Agric. Biochem.
25
1-7
2012
Ananas comosus (O23791)
-
brenda
Mohan, R.; Sivakumar, V.; Rangasamy, T.; Muralidharan, C.
Optimisation of bromelain enzyme extraction from pineapple (Ananas comosus) and application in process industry
Am. J. Biochem. Biotechnol.
12
188-195
2016
Ananas comosus (O23791)
-
brenda
Misran, E.; Idris, A.; Mat Sarip, S.; Yaakob, H.
Properties of bromelain extract from different parts of the pineapple variety Morris
Biocatal. Agricult. Biotechnol.
18
101095
2019
Ananas comosus
-
brenda
Ramli, A.N.M.; Manas, N.H.A.; Hamid, A.A.A.; Hamid, H.A.; Illias, R.M.
Comparative structural analysis of fruit and stem bromelain from Ananas comosus
Food Chem.
266
183-191
2018
Ananas comosus (O23791), Ananas comosus
brenda
Meza-Espinoza, L.; de Los Angeles Vivar-Vera, M.; de Lourdes Garcia-Magana, M.; Sayago-Ayerdi, S.G.; Chacon-Lopez, A.; Becerrea-Verdin, E.M.; Montalvo-Gonzalez, E.
Enzyme activity and partial characterization of proteases obtained from Bromelia karatas fruit and compared with Bromelia pinguin proteases
Food Sci. Biotechnol.
27
509-517
2018
Bromelia pinguin, Bromelia karatas
brenda
Chakraborty, S.; Rao, P.; Mishra, H.
Modeling the inactivation kinetics of fruit bromelain in pineapple during high-pressure and thermal treatments
Innov. Food Sci. Emerg. Technol.
33
10-18
2016
Ananas comosus (O23791)
-
brenda
Sao Paulo Barretto Miranda, I.K.; Fontes Suzart Miranda, A.; Souza, F.V.; Vannier-Santos, M.A.; Pirovani, C.P.; Pepe, I.M.; Rodowanski, I.J.; Ferreira, K.T.; Mendes Souza Vaz, L.; de Assis, S.A.
The biochemical characterization, stabilization studies and the antiproliferative effect of bromelain against B16F10 murine melanoma cells
Int. J. Food Sci. Nutr.
68
442-454
2017
Ananas comosus (O23791), Ananas comosus (O23801), Ananas comosus AGB 772 (O23791), Ananas comosus AGB 772 (O23801)
brenda
Das, S.; Bhattacharyya, D.
Destabilization of human insulin fibrils by peptides of fruit bromelain derived from Ananas comosus (pineapple)
J. Cell. Biochem.
118
4881-4896
2017
Ananas comosus (O23791), Ananas comosus
brenda
Ghensi, P.; Cucchi, A.; Bonaccorso, A.; Ferroni, L.; Gardin, C.; Mortellaro, C.; Zavan, B.
In vitro effect of bromelain on the regenerative properties of mesenchymal stem cells
J. Craniofac. Surg.
30
1064-1067
2019
Ananas comosus (O24641)
brenda
Andjaitan, M.; Tutunnugrah, T.; Pamudja, K.; Idris, F.; Tjandra, M.; Wiriantono, T.
Bromelain enzyme from pineapple fruit as an antiviral agent against HIV, hepatitis C and human papiloma virus
J. Eng. Appl. Sci.
13
3125-3130
2018
Ananas comosus (O23791)
-
brenda
Zhi, N.; Zong, K.; Jia, X.; Wang, L.; Liang, J.
Effect of high pressure processing on fibrinolytic activity of fruit bromelain in vivo
J. Food Process Eng.
42
e13146
2019
Ananas comosus (O23791)
-
brenda
Kaur, T.; Kaur, A.; Grewal, R.K.
Kinetics studies with fruit bromelain (Ananas comosus) in the presence of cysteine and divalent ions
J. Food Sci. Technol.
52
5954-5960
2015
Ananas comosus (O23791)
brenda