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Reference on EC 3.4.21.B26 - proprotein convertase 5 and Organism(s) Mus musculus and UniProt Accession Q04592

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Basak, A.; Zhong, M.; Munzer, J.S.; Chretien, M.; Seidah, N.G.
Implication of the proprotein convertases furin, PC5 and PC7 in the cleavage of surface glycoproteins of Hong Kong, Ebola and respiratory syncytial viruses: a comparative analysis with fluorogenic peptides
Biochem. J.
353
537-545
2001
Mus musculus
Manually annotated by BRENDA team
De Strooper, B.; Creemers, J.W.; Moechars, D.; Huylebroeck, D.; Van De Ven, W.J.; Van Leuven, F.; Van den Berghe, H.
Amyloid precursor protein is not processed by furin, PACE 4, PC1/3, PC2, PC4 and PC5/6 of the furin family of proprotein processing enzymes
Biochim. Biophys. Acta
1246
185-188
1995
Mus musculus
Manually annotated by BRENDA team
De Bie, I.; Marcinkiewicz, M.; Malide, D.; Lazure, C.; Nakayama, K.; Bendayan, M.; Seidah, N.G.
The isoforms of proprotein convertase PC5 are sorted to different subcellular compartments
J. Cell. Biol.
135
1261-1275
1996
Mus musculus
Manually annotated by BRENDA team
Tang, M.; Mikhailik, A.; Pauli, I.; Giudice, L.C.; Fazelabas, A.T.; Tulac, S.; Carson, D.D.; Kaufman, D.G.; Barbier, C.; Creemers, J.W.; Tabibzadeh, S.
Decidual differentiation of stromal cells promotes proprotein convertase 5/6 expression and lefty processing
Endocrinology
146
5313-5320
2005
Mus musculus (Q04592), Mus musculus
Manually annotated by BRENDA team
Seidah, N.G.; Chretien, M.
Proprotein convertase 5
Handbook of Proteolytic Enzymes (Barrett, A. J. , Rawlings, N. D. , Woessner, J. F. , Eds. ) Academic Press
2
1874-1877
2004
Homo sapiens, Mus musculus, Rattus norvegicus
-
Manually annotated by BRENDA team
Essalmani, R.; Hamelin, J.; Marcinkiewicz, J.; Chamberland, A.; Mbikay, M.; Chretien, M.; Seidah, N.G.; Prat, A.
Deletion of the gene encoding proprotein convertase 5/6 causes early embryonic lethality in the mouse
Mol. Cell. Biol.
26
354-361
2006
Homo sapiens (Q92824), Mus musculus
Manually annotated by BRENDA team
Stein, J.; Shah, R.; Steiner, D.F.; Dey, A.
RNAi-mediated silencing of prohormone convertase (PC) 5/6 expression leads to impairment in processing of cocaine- and amphetamine-regulated transcript (CART) precursor
Biochem. J.
400
209-215
2006
Mus musculus (Q04592)
Manually annotated by BRENDA team
Dikeakos, J.D.; Mercure, C.; Lacombe, M.; Seidah, N.G.; Reudelhuber, T.L.
PC1/3, PC2 and PC5/6A are targeted to dense core secretory granules by a common mechanism
FEBS J.
274
4094-4102
2007
Mus musculus
Manually annotated by BRENDA team
Seidah, N.G.; Mayer, G.; Zaid, A.; Rousselet, E.; Nassoury, N.; Poirier, S.; Essalmani, R.; Prat, A.
The activation and physiological functions of the proprotein convertases
Int. J. Biochem. Cell Biol.
40
1111-1125
2008
Mus musculus (Q04592)
Manually annotated by BRENDA team
Mayer, G.; Hamelin, J.; Asselin, M.; Pasquato, A.; Marcinkiewicz, E.; Tang, M.; Tabibzadeh, S.; Seidah, N.G.
The regulated cell surface zymogen activation of the proprotein convertase PC5A directs the processing of its secretory substrates
J. Biol. Chem.
283
2373-2384
2008
Mus musculus (Q04592)
Manually annotated by BRENDA team
Reynolds Nicole , R.N.; Blum Aliss, B.A.; Kitagawa Kouk, K.K.; Beinfeld, M.C.
Inhibition of PC5 expression decreases CCK secretion and increases PC2 expression
Peptides
27
901-904
2006
Mus musculus (Q04592), Mus musculus
Manually annotated by BRENDA team
Padua, M.B.; Hansen, P.J.
Regulation of DNA synthesis and the cell cycle in human prostate cancer cells and lymphocytes by ovine uterine serpin
BMC Cell Biol.
9
5
2008
Mus musculus (Q04592)
Manually annotated by BRENDA team
Essalmani, R.; Zaid, A.; Marcinkiewicz, J.; Chamberland, A.; Pasquato, A.; Seidah, N.G.; Prat, A.
In vivo functions of the proprotein convertase PC5/6 during mouse development: Gdf11 is a likely substrate
Proc. Natl. Acad. Sci. USA
105
5750-5755
2008
Mus musculus (Q04592), Mus musculus
Manually annotated by BRENDA team
Xiao, Y.; Chen, G.; Richard, J.; Rougeau, N.; Li, H.; Seidah, N.G.; Cohen, E.A.
Cell-surface processing of extracellular human immunodeficiency virus type 1 Vpr by proprotein convertases
Virology
372
384-397
2008
Mus musculus (Q04592)
Manually annotated by BRENDA team
Sun, X.; Essalmani, R.; Seidah, N.G.; Prat, A.
The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model
Mol. Cancer
8
73
2009
Mus musculus
Manually annotated by BRENDA team
Fritzsche, J.; Stawowy, P.
Time for endothelial cell proprotein convertase PC5/6 in cardiovascular medicine?
J. Mol. Med.
89
1061-1063
2011
Mus musculus
Manually annotated by BRENDA team
Hoac, B.; Susan-Resiga, D.; Essalmani, R.; Marcinkiweicz, E.; Seidah, N.G.; McKee, M.D.
Osteopontin as a novel substrate for the proprotein convertase 5/6 (PCSK5) in bone
Bone
107
45-55
2018
Mus musculus (Q04592)
Manually annotated by BRENDA team