Reference on EC 2.7.11.24 - mitogen-activated protein kinase and Organism(s) Rattus norvegicus and UniProt Accession P49187
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Boulton, T.G.; Gregory, J.S.; Cobb, M.H.
Purification and properties of extracellular signal-regulated kinase 1, an insulin-stimulated microtubule-associated protein 2 kinase
Biochemistry
30
278-286
1991
Rattus norvegicus (P21708)
Hu, M.C.; Wang, Y.P.; Mikhail, A.; Qiu, W.R.; Tan, T.H.
Murine p38-delta mitogen-activated protein kinase, a developmentally regulated protein kinase that is activated by stress and proinflammatory cytokines
J. Biol. Chem.
274
7095-7102
1999
Homo sapiens (O15264), Homo sapiens, Rattus norvegicus (Q9WTY9)
Yung, Y.; Yao, Z.; Hanoch, T.; Seger, R.
ERK1b, a 46-kDa ERK isoform that is differentially regulated by MEK
J. Biol. Chem.
275
15799-15808
2000
Rattus norvegicus (P21708)
Marquardt, B.; Stabel, S.
Sequence of a rat cDNA encoding the ERK1-MAP kinase
Gene
120
297-299
1992
Rattus norvegicus (P21708)
Seger, R.; Ahn, N.G.; Boulton, T.G.; Yancopoulos, G.D.; Panayotatos, N.; Radziejewska, E.; Ericsson, L.; Bratlien, R.L.; Cobb, M.H.; Krebs, E.G.
Microtubule-associated protein 2 kinases, ERK1 and ERK2, undergo autophosphorylation on both tyrosine and threonine residues: implications for their mechanism of activation
Proc. Natl. Acad. Sci. USA
88
6142-6146
1991
Rattus norvegicus (P21708)
De Miguel, C.; Kligman, D.; Patel, J.; Detera-Wadleigh, S.D.
Molecular analysis of microtubule-associated protein-2 kinase cDNA from mouse and rat brain
DNA Cell Biol.
10
505-514
1991
Rattus norvegicus (P21708)
Boulton, T.G.; Yancopoulos, G.D.; Gregory, J.S.; Slaughter, C.; Moomaw, C.; Hsu, J.; Cobb, M.H.
An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control
Science
249
64-67
1990
Rattus norvegicus (P21708)
Boulton, T.G.; Nye, S.H.; Robbins, D.J.; Ip, N.Y.; Radziejewska, E.; Morgenbesser, S.D.; DePinho, R.A.; Panayotatos, N.; Cobb, M.H.; Yancopoulos, G.D.
ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF
Cell
65
663-675
1991
Rattus norvegicus (P27704), Mus musculus (P63085)
Clerk, A.; Fuller, S.J.; Michael, A.; Sugden, P.H.
Stimulation of "stress-regulated" mitogen-activated protein kinases (stress-activated protein kinases/c-Jun N-terminal kinases and p38-mitogen-activated protein kinases) in perfused rat hearts by oxidative and other stresses
J. Biol. Chem.
273
7228-7234
1998
Rattus norvegicus (P49185)
Kyriakis, J.M.; Banerjee, P.; Nikolakaki, E.; Dai, T.; Rubie, E.A.; Ahmad, M.F.; Avruch, J.; Woodgett, J.R.
The stress-activated protein kinase subfamily of c-Jun kinases
Nature
369
156-160
1994
Rattus norvegicus (P49185), Rattus norvegicus (P49186), Rattus norvegicus (P49187)
Royo, M.; Daubner, S.C.; Fitzpatrick, P.F.
Specificity of the MAP kinase ERK2 for phosphorylation of tyrosine hydroxylase
Arch. Biochem. Biophys.
423
247-252
2004
Rattus norvegicus
Lee, J.Y.; Yu, B.P.; Chung, H.Y.
Activation mechanisms of endothelial NF-kappaB, IKK, and MAP kinase by tert-butyl hydroperoxide
Free Radic. Res.
39
399-409
2005
Rattus norvegicus
Buckley, C.T.; Sekiya, F.; Kim, Y.J.; Rhee, S.G.; Caldwell, K.K.
Identification of phospholipase C-gamma1 as a mitogen-activated protein kinase substrate
J. Biol. Chem.
279
41807-41814
2004
Rattus norvegicus, Rattus norvegicus (P63086)
Samuvel, D.J.; Jayanthi, L.D.; Bhat, N.R.; Ramamoorthy, S.
A role for p38 mitogen-activated protein kinase in the regulation of the serotonin transporter: evidence for distinct cellular mechanisms involved in transporter surface expression
J. Neurosci.
25
29-41
2005
Rattus norvegicus
Bind, E.; Kleyner, Y.; Skowronska-Krawczyk, D.; Bien, E.; Dynlacht, B.D.; Sanchez, I.
A novel mechanism for mitogen-activated protein kinase localization
Mol. Biol. Cell
15
4457-4466
2004
Rattus norvegicus (P27704)
Ravingerova, T.; Barancik, M.; Strniskova, M.
Mitogen-activated protein kinases: a new therapeutic target in cardiac pathology
Mol. Cell. Biochem.
247
127-138
2003
Canis lupus familiaris, Oryctolagus cuniculus, Homo sapiens, Mus musculus, Rattus norvegicus, Sus scrofa
Lewthwaite, J.C.; Bastow, E.R.; Lamb, K.J.; Blenis, J.; Wheeler-Jones, C.P.; Pitsillides, A.A.
A specific mechanomodulatory role for p38 MAPK in embryonic joint articular surface cell MEK-ERK pathway regulation
J. Biol. Chem.
281
11011-11018
2006
Gallus gallus, Rattus norvegicus
Murphy, L.O.; Blenis, J.
MAPK signal specificity: the right place at the right time
Trends Biochem. Sci.
31
268-275
2006
Rattus norvegicus, Xenopus sp.
Liu, C.; Lin, J.; Pitt, S.; Zhang, R.F.; Sack, J.S.; Kiefer, S.E.; Kish, K.; Doweyko, A.M.; Zhang, H.; Marathe, P.H.; Trzaskos, J.; Mckinnon, M.; Dodd, J.H.; Barrish, J.C.; Schieven, G.L.; Leftheris, K.
Benzothiazole based inhibitors of p38alpha MAP kinase
Bioorg. Med. Chem. Lett.
18
1874-1879
2008
Rattus norvegicus (P70618)
Chen, L.; Liu, L.; Huang, S.
Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5
Free Radic. Biol. Med.
45
1035-1044
2008
Homo sapiens, Homo sapiens (P27361), Homo sapiens (P28482), Rattus norvegicus, Rattus norvegicus (P21708), Rattus norvegicus (P63086)
Hamel, M.G.; Ajmo, J.M.; Leonardo, C.C.; Zuo, F.; Sandy, J.D.; Gottschall, P.E.
Multimodal signaling by the ADAMTSs (a disintegrin and metalloproteinase with thrombospondin motifs) promotes neurite extension
Exp. Neurol.
210
428-440
2008
Rattus norvegicus
Chen, B.; Ma, Y.; Meng, R.; Xiong, Z.; Zhang, C.; Chen, G.; Zhang, A.; Dong, Y.
MG132, a proteasome inhibitor, attenuates pressure-overload-induced cardiac hypertrophy in rats by modulation of mitogen-activated protein kinase signals
Acta Biochim. Biophys. Sin. (Shanghai)
42
253-258
2010
Rattus norvegicus
Li, F.; Ruan, H.; Fan, C.; Zeng, B.; Wang, C.; Wang, X.
Efficient inhibition of the formation of joint adhesions by ERK2 small interfering RNAs
Biochem. Biophys. Res. Commun.
391
795-799
2010
Rattus norvegicus
Fahrenholz, M.; Real, R.; Kueken, A.; Saxena, A.; Orzechowski, H.D.
Single low-dose administration of pharmacological inhibitor of mitogen-activated ERK kinase to the adventitia of the injured rat carotid artery suppresses neointima formation and inhibits nuclear ERK signaling
Eur. J. Pharmacol.
617
90-96
2009
Rattus norvegicus
Chang, Y.; Wang, S.J.
Hypericin, the active component of St. Johns wort, inhibits glutamate release in the rat cerebrocortical synaptosomes via a mitogen-activated protein kinase-dependent pathway
Eur. J. Pharmacol.
634
53-61
2010
Rattus norvegicus
Hanajiri, K.; Mitsui, H.; Maruyama, T.; Hashimoto, N.; Sata, M.; Omata, M.
Echographic detection of diethylnitrosamine-induced liver tumors in rats and the effect of the intratumoral injection of an inhibitor of c-Jun N-terminal kinase
J. Gastroenterol. Hepatol.
24
866-871
2009
Rattus norvegicus
Lizarraga-Mollinedo, E.; Fernandez-Millan, E.; de Miguel-Santos, L.; Martinez-Honduvilla, C.J.; Alvarez, C.; Escriva, F.
Early undernutrition increases glycogen content and reduces the activated forms of GSK3, AMPK, p38 MAPK, and JNK in the cerebral cortex of suckling rats
J. Neurochem.
112
123-133
2010
Rattus norvegicus
Stamboulian, S.; Choi, J.S.; Ahn, H.S.; Chang, Y.W.; Tyrrell, L.; Black, J.A.; Waxman, S.G.; Dib-Hajj, S.D.
ERK1/2 mitogen-activated protein kinase phosphorylates sodium channel Na(v)1.7 and alters its gating properties
J. Neurosci.
30
1637-1647
2010
Rattus norvegicus
Onali, P.; Dedoni, S.; Olianas, M.C.
Direct agonist activity of tricyclic antidepressants at distinct opioid receptor subtypes
J. Pharmacol. Exp. Ther.
332
255-265
2010
Homo sapiens, Rattus norvegicus
Vikram, A.; Jena, G.B.; Ramarao, P.
Increased cell proliferation and contractility of prostate in insulin resistant rats: linking hyperinsulinemia with benign prostate hyperplasia
Prostate
70
79-89
2010
Rattus norvegicus
Blaha, L.; Babica, P.; Hilscherova, K.; Upham, B.L.
Inhibition of gap-junctional intercellular communication and activation of mitogen-activated protein kinases by cyanobacterial extracts--indications of novel tumor-promoting cyanotoxins?
Toxicon
55
126-134
2010
Rattus norvegicus
Xiao, Y.; Warner, L.R.; Latham, M.P.; Ahn, N.G.; Pardi, A.
Structure-based assignment of Ile, Leu, and Val methyl groups in the active and inactive forms of the mitogen-activated protein kinase extracellular signal-regulated kinase 2
Biochemistry
54
4307-4319
2015
Rattus norvegicus (P63086)
