Reference on EC 2.4.1.69 - type 1 galactoside alpha-(1,2)-fucosyltransferase and Organism(s) Homo sapiens and UniProt Accession P19526
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Scudder, P.R.; Chantler, E.N.
Glycosyltransferases of the human cervical epithelium. I. Characterization of a beta-galactoside alpha-2-L-fucosyltransferase and the identification of a beta-N-acetylglucosaminide alpha-3-L-fucosyltransferase
Biochim. Biophys. Acta
660
128-135
1981
Homo sapiens
Kyprianou, P.; Betteridge, A.; Donald, A.S.R.; Watkins, W.M.
Purification of the blood group H gene associated alpha-2-L-fucosyltransferase from human plasma
Glycoconjugate J.
7
573-588
1990
Homo sapiens
Chester, M.A.; Yates, A.D.; Watkins, W.M.
Phenyl beta-D-galactosylpyranoside as an acceptor substrate for the blood-group H gene-associated guanosine diphosphate L-fucose:beta-D-galactosyl alpha-2-L-fucosyltransferase
Eur. J. Biochem.
69
583-592
1976
Homo sapiens
-
Sarnesto, A.; Koehlin, T.; Thurin, J.; Blaszczyk-Thurin, M.
Purification of Hgene-encoded beta-galactoside alpha 1->2 fucosyltransferase from human serum
J. Biol. Chem.
265
15067-15075
1990
Homo sapiens
Sarnesto, A.; Koehlin, T.; Hindsgaul, O.; Thurin, J.; Blaszczyk-Thurin, M.
Purification of the secretor-type beta-galactoside alpha 1->2-fucosyltransferase from human serum
J. Biol. Chem.
267
2737-2744
1992
Homo sapiens
Pacuszka, T.; Koscielak, J.
alpha 1->2 Fucosyltransferase of human bone marrow
FEBS Lett.
41
348-351
1974
Homo sapiens
Chou, T.H.; Murphy, C.; Kessel, D.
Selective inhibition of a plasma fucosyltransferase by N-ethylmaleimide
Biochem. Biophys. Res. Commun.
74
1001-1006
1977
Homo sapiens
Prieto, P.A.; Larsen, R.D.; Cho, M.; Rivera, H.N.; Shilatifard, A.; Lowe, J.B.; Cummings, R.D.; Smith, D.F.
Expression of human H-type alpha1,2-fucosyltransferase encoding for blood group H(O) antigen in Chinese hamster ovary cells. Evidence for preferential fucosylation and truncation of polylactosamine sequences
J. Biol. Chem.
272
2089-2097
1997
Homo sapiens
Domino, S.E.; Hiraiwa, N.; Lowe, J.B.
Molecular cloning, chromosomal assignment and tissue-specific expression of a murine alpha-(1,2)fucosyltransferase expressed in thymic and epididymal epithelial cells
Biochem. J.
327
105-115
1997
Homo sapiens, Mus musculus
-
Masutani, H.; Kimura, H.
Purification and characterization of secretory-type GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase from human gastric mucosa
J. Biochem.
118
541-545
1995
Homo sapiens
Marker, P.C.; Stephan, J.P.; Lee, J.; Bald, L.; Mather, J.P.; Cunha, G.R.
Fucosyltransferase1 and H-type complex carbohydrates modulate epithelial cell proliferation during prostatic branching morphogenesis
Dev. Biol.
233
95-108
2001
Homo sapiens, Rattus norvegicus
Chandrasekaran, E.V.; Chawda, R.; Locke, R.D.; Piskorz, C.F.; Matta, K.L.
Biosynthesis of the carbohydrate antigenic determinants, Globo H, blood group H, and Lewis b: a role for prostate cancer cell alpha1,2-L-fucosyltransferase
Glycobiology
12
153-162
2002
Homo sapiens
Koda, Y.; Soejima, M.; Kimura, H.
Changing transcription start sites in H-type alpha(1,2)fucosyltransferase gene (FUT1) during differentiation of the human erythroid lineage
Eur. J. Biochem.
256
379-387
1998
Homo sapiens
Chandrasekaran, E.V.; Jain, R.K.; Larsen, R.D.; Wlasichuk, K.; Matta, K.L.
Characterization of the specificities of human blood group H gene-specified alpha1,2-L-fucosyltransferase toward sulfated/sialylated/fucosylated acceptors: evidence for an inverse relationship between alpha1,2-L-fucosylation of Gal and alpha1,6-L-fucosylation of asparagine-linked GlcNAc
Biochemistry
35
8914-8924
1996
Homo sapiens
Yan, J.L.; Yu, L.Y.; Guo, L.H.
Human alpha galactosidase and alpha 1,2 fucosyltransferase concordantly inhibit xenoreactivity of NIH 3T3 cells with human serum
Acta Pharmacol. Sin.
24
878-884
2003
Homo sapiens
Mathieu, S.; Prorok, M.; Benoliel, A.M.; Uch, R.; Langlet, C.; Bongrand, P.; Gerolami, R.; El-Battari, A.
Transgene expression of alpha(1,2)-fucosyltransferase-I (FUT1) in tumor cells selectively inhibits sialyl-lewis x expression and binding to E-selectin without affecting synthesis of sialyl-Lewis a or binding to P-selectin
Am. J. Pathol.
164
371-383
2004
Homo sapiens
Serpa, J.; Mendes, N.; Reis, C.A.; Santos Silva, L.F.; Almeida, R.; Le Pendu, J.; David, L.
Two new FUT2 (fucosyltransferase 2 gene) missense polymorphisms, 739G-->A and 839T-->C, are partly responsible for non-secretor status in a Caucasian population from Northern Portugal
Biochem. J.
383
469-474
2004
Homo sapiens
Iwamori, M.; Tanaka, K.; Kubushiro, K.; Lin, B.; Kiguchi, K.; Ishiwata, I.; Tsukazaki, K.; Nozawa, S.
Alterations in the glycolipid composition and cellular properties of ovarian carcinoma-derived RMG-1 cells on transfection of the alpha1,2-fucosyltransferase gene
Cancer Sci.
96
26-30
2005
Homo sapiens (P19526), Homo sapiens, Mus musculus (P97327), Mus musculus (Q9JL27), Mus musculus
Sepp, A.; Skacel, P.; Lindstedt, T.; Lechler, R.I.
Expression of alpha(1,3)galactose and other type 2 oligosaccharide structures in a porcine endothelial cell line transfected with human alpha(1,2)-fucosyltransferase cDNA
J. Biol. Chem.
272
23104-23110
1997
Homo sapiens
Kindberg, E.; Hejdeman, B.; Bratt, G.; Wahren, B.; Lindblom, B.; Hinkula, J.; Svensson, L.
A nonsense mutation (428G-->A) in the fucosyltransferase FUT2 gene affects the progression of HIV-1 infection
AIDS
20
685-689
2006
Homo sapiens
Park, K.U.; Song, J.; Han, K.S.; Kim, J.Q.
The fusion allele of the FUT2 (secretor type alpha(1,2)-fucosyltransferase) gene at a high frequency and a new se385 allele in a Korean population
Ann. Hematol.
84
656-660
2005
Homo sapiens
Holgersson, J.; Loefling, J.
Glycosyltransferases involved in type 1 chain and Lewis antigen biosynthesis exhibit glycan and core chain specificity
Glycobiology
16
584-593
2006
Homo sapiens
Chandrasekaran, E.V.; Xue, J.; Piskorz, C.; Locke, R.D.; Toth, K.; Slocum, H.K.; Matta, K.L.
Potential tumor markers for human gastric cancer: an elevation of glycan:sulfotransferases and a concomitant loss of alpha1,2-fucosyltransferase activities
J. Cancer Res. Clin. Oncol.
133
599-611
2007
Homo sapiens
Thorven, M.; Grahn, A.; Hedlund, K.O.; Johansson, H.; Wahlfrid, C.; Larson, G.; Svensson, L.
A homozygous nonsense mutation (428G-->A) in the human secretor (FUT2) gene provides resistance to symptomatic norovirus (GGII) infections
J. Virol.
79
15351-15355
2005
Homo sapiens
Nilsson, C.; Skoglund, A.; Moran, A.P.; Annuk, H.; Engstrand, L.; Normark, S.
An enzymatic ruler modulates Lewis antigen glycosylation of Helicobacter pylori LPS during persistent infection
Proc. Natl. Acad. Sci. USA
103
2863-2868
2006
Homo sapiens
Meng, D.; Newburg, D.S.; Young, C.; Baker, A.; Tonkonogy, S.L.; Sartor, R.B.; Walker, W.A.; Nanthakumar, N.N.
Bacterial symbionts induce a FUT2-dependent fucosylated niche on colonic epithelium via ERK and JNK signaling
Am. J. Physiol. Gastrointest. Liver Physiol.
293
G780-G787
2007
Homo sapiens
Soejima, M.; Koda, Y.
Distinct single nucleotide polymorphism pattern at the FUT2 promoter among human populations
Ann. Hematol.
87
19-25
2008
Homo sapiens
Mathieu, S.; Gerolami, R.; Luis, J.; Carmona, S.; Kol, O.; Crescence, L.; Garcia, S.; Borentain, P.; El-Battari, A.
Introducing alpha(1,2)-linked fucose into hepatocarcinoma cells inhibits vasculogenesis and tumor growth
Int. J. Cancer
121
1680-1689
2007
Homo sapiens
Moehler, T.M.; Sauer, S.; Witzel, M.; Andrulis, M.; Garcia-Vallejo, J.J.; Grobholz, R.; Willhauck-Fleckenstein, M.; Greiner, A.; Goldschmidt, H.; Schwartz-Albiez, R.
Involvement of alpha 1-2-fucosyltransferase I (FUT1) and surface-expressed Lewis(y) (CD174) in first endothelial cell-cell contacts during angiogenesis
J. Cell. Physiol.
215
27-36
2008
Homo sapiens
Yip, S.P.; Lai, S.K.; Wong, M.L.
Systematic sequence analysis of the human fucosyltransferase 2 (FUT2) gene identifies novel sequence variations and alleles
Transfusion
47
1369-1380
2007
Homo sapiens (Q10981), Homo sapiens
Silva, L.M.; Carvalho, A.S.; Guillon, P.; Seixas, S.; Azevedo, M.; Almeida, R.; Ruvoen-Clouet, N.; Reis, C.A.; Le Pendu, J.; Rocha, J.; David, L.
Infection-associated FUT2 (Fucosyltransferase 2) genetic variation and impact on functionality assessed by in vivo studies
Glycoconj. J.
27
61-68
2010
Homo sapiens
Abrantes, J.; Posada, D.; Guillon, P.; Esteves, P.J.; Le Pendu, J.
Widespread gene conversion of alpha-2-fucosyltransferase genes in mammals
J. Mol. Evol.
69
22-31
2009
Bos taurus (A4IFH1), Bos taurus (Q28113), Bos taurus (Q9TTY3), Chlorocebus sabaeus, Chlorocebus sabaeus (O77711), Chlorocebus sabaeus (O77712), Gorilla gorilla (O77486), Gorilla gorilla (Q9TUD4), Homo sapiens (P19526), Homo sapiens (Q10981), Homo sapiens (Q5XLR8), Homo sapiens, Hylobates agilis (Q6LA46), Hylobates lar (Q9TTC7), Macaca fascicularis (Q9N266), Monodelphis domestica, Mus musculus (O09160), Mus musculus (P97353), Oryctolagus cuniculus (Q10979), Oryctolagus cuniculus (Q10983), Oryctolagus cuniculus (Q29505), Oryctolagus cuniculus, Pan troglodytes (O77485), Pan troglodytes (Q9TUD6), Pongo pygmaeus (O77487), Pongo pygmaeus (Q6LA45), Rattus norvegicus (Q10980), Rattus norvegicus (Q10984), Rattus norvegicus (Q9WUE6), Sus scrofa (Q10982), Sus scrofa (Q29043), Xenopus tropicalis
Hazra, A.; Kraft, P.; Selhub, J.; Giovannucci, E.L.; Thomas, G.; Hoover, R.N.; Chanock, S.J.; Hunter, D.J.
Common variants of FUT2 are associated with plasma vitamin B12 levels
Nat. Genet.
40
1160-1162
2008
Homo sapiens (Q10981)
Carlsson, B.; Kindberg, E.; Buesa, J.; Rydell, G.E.; Lidon, M.F.; Montava, R.; Abu Mallouh, R.; Grahn, A.; Rodriguez-Diaz, J.; Bellido, J.; Arnedo, A.; Larson, G.; Svensson, L.
The G428A nonsense mutation in FUT2 provides strong but not absolute protection against symptomatic GII.4 Norovirus infection
PLoS ONE
4
e5593
2009
Homo sapiens (Q10981)
Tao, S.; He, Y.; Ying, Y.; Hong, X.; Xu, X.; Zhu, F.; Lv, H.; Yan, L.
C35T mutation could slightly decrease the activity of human alpha-(1,2)-fucosyltransferase
Transfus. Clin. Biol.
19
5-10
2012
Homo sapiens
Zeyland, J.; Wozniak, A.; Gawronska, B.; Juzwa, W.; Jura, J.; Nowak, A.; S?omski, R.; Smorag, Z.; Szalata, M.; Mazurek, U.; Lipinski, D.
Double transgenic pigs with combined expression of human alpha1,2-fucosyltransferase and alpha-galactosidase designed to avoid hyperacute xenograft rejection
Arch. Immunol. Ther. Exp.
62
411-422
2014
Homo sapiens (P19526)
Isozaki, T.; Ruth, J.H.; Amin, M.A.; Campbell, P.L.; Tsou, P.S.; Ha, C.M.; Haines, G.K.; Edhayan, G.; Koch, A.E.
Fucosyltransferase 1 mediates angiogenesis, cell adhesion and rheumatoid arthritis synovial tissue fibroblast proliferation
Arthritis Res. Ther.
16
R28
2014
Homo sapiens (P19526)
Gao, N.; Liu, J.; Liu, D.; Hao, Y.; Yan, L.; Ma, Y.; Zhuang, H.; Hu, Z.; Gao, J.; Yang, Z.; Shi, H.; Lin, B.
c-Jun transcriptionally regulates alpha 1, 2-fucosyltransferase 1 (FUT1) in ovarian cancer
Biochimie
107 Pt B
286-292
2014
Homo sapiens (P19526)
Che, Y.; Ren, X.; Xu, L.; Ding, X.; Zhang, X.; Sun, X.
Critical involvement of the alpha(1,2)-fucosyltransferase in multidrug resistance of human chronic myeloid leukemia
Oncol. Rep.
35
3025-3033
2016
Homo sapiens (P19526)
Dicioccio, R.A.; Barlow, J.J.; Matta, K.L.
Modified procedure for detection of GDP-L-fucose:galactoside 2-fucosyltransferase
Clin. Chim. Acta
108
41-48
1980
Homo sapiens
