Protein Variants | Comment | Organism |
---|---|---|
F280S | missense polymorphism, almost inactive enzyme, responsible for some non-secretor cases | Homo sapiens |
G247S | missense polymorphism, almost inactive enzyme, responsible for some non-secretor case | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | KM-value for asialofetuin: 3.33 mg/ml | Homo sapiens | |
0.05 | - |
GDP-fucose | pH 6.0, 37°C. wild-type enzyme | Homo sapiens | |
0.0909 | - |
GDP-fucose | pH 6.0, 37°Cmutant enzyme F280SS | Homo sapiens | |
0.178 | - |
GDP-fucose | pH 6.0, 37°C, mutant enzyme G247S | Homo sapiens | |
8.79 | - |
phenyl beta-D-galactoside | pH 6.0, 37°C. wild-type enzyme | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
two fucosyltransferase 2 gene missense polymorphisms, G247S and F280S, are partly responsible for non-secretor status in a Caucasian population from Northern Portugal | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GDP-fucose + asialofetuin | - |
Homo sapiens | GDP + asialofetuin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
fucosyltransferase 2 | - |
Homo sapiens |
FUT2 | - |
Homo sapiens |