6.3.5.1: NAD+ synthase (glutamine-hydrolysing)

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For detailed information about NAD+ synthase (glutamine-hydrolysing), go to the full flat file.

Word Map on EC 6.3.5.1

6.3.5.1

ammonia

synthetases

nicotinic

typhimurium

nitrilase

glutaminase

ammonia-dependent

nitrogen-limiting

enhancer-binding

tuberculosis

nh3-dependent

salvage

adenylyltransferase

amidotransferase

synthesis

medicine

Reaction

Synonyms

abNadE, General stress protein 38, glutamine-dependent NAD synthetase, glutamine-dependent NAD+ synthetase, glutamine-dependent NadEGln, GSP38, Hsero_1894, mtuNadE, NAD synthetase (glutamine), NAD(+) synthase [glutamine-hydrolyzing], NAD+ synthase, NAD+ synthetase, NAD+ synthetase (glutamine-hydrolysing), NadE-679, NadE-738, NadE1, NADS, nic13, Nicotinamide adenine dinucleotide synthetase (glutamine), nicotinamide adenine dinucleotide synthetase enzyme, Nitrogen-regulatory protein, Qns1, Sporulation protein outB, Synthetase, nicotinamide adenine dinucleotide (glutamine)

ECTree

6 Ligases

6.3 Forming carbon-nitrogen bonds

6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor

6.3.5.1 NAD+ synthase (glutamine-hydrolysing)

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Results	in table
2	Activating Compound
29511	AA Sequence
2	Application
1	CAS Registry Number
10	Cloned(Commentary)
3	Cofactor
2	Crystallization (Commentary)
5	Disease/ Diagnostics
8	General Information
2	General Stability
4	IC50 Value
15	Inhibitors
18	kcat/KM [mM/s]
1	Ki Value [mM]
65	KM Value [mM]
12	Metals/Ions
11	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
22	Organism
12	Pathway
44	PDB ID
8	pH Optimum
2	pH Range
1	pH Stability
30	Protein Variants
10	Purification (Commentary)
1	Reaction
1	Reaction Type
21	Reference
19	Source Tissue
25	Specific Activity [micromol/min/mg]
2	Storage Stability
35	Substrates and Products (Substrate)
7	Subunits
36	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
21	Turnover Number [1/s]

Source Tissue

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Source Tissue on EC 6.3.5.1 - NAD+ synthase (glutamine-hydrolysing)

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brain

Homo sapiens

Q6IA69

the major sites of NADsyn1 gene expression are the small intestine, kidney, liver, and testis, whereas the skeletal muscle, spleen, lung, heart, and brain show a weak signal

wild-type Nicotiana sylvestris and the CMSII mutant that lacks respiratory complex I show different NADS mRNA expression pattern

the major sites of NADsyn1 gene expression are the small intestine, kidney, liver, and testis, whereas the skeletal muscle, spleen, lung, heart, and brain show a weak signal

the major sites of NADsyn1 gene expression are the small intestine, kidney, liver, and testis, whereas the skeletal muscle, spleen, lung, heart, and brain show a weak signal

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the major sites of NADsyn1 gene expression are the small intestine, kidney, liver, and testis, whereas the skeletal muscle, spleen, lung, heart, and brain show a weak signal