6.3.5.1: NAD+ synthase (glutamine-hydrolysing)

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For detailed information about NAD+ synthase (glutamine-hydrolysing), go to the full flat file.

Reaction

Synonyms

abNadE, General stress protein 38, glutamine-dependent NAD synthetase, glutamine-dependent NAD+ synthetase, glutamine-dependent NadEGln, GSP38, Hsero_1894, mtuNadE, NAD synthetase (glutamine), NAD(+) synthase [glutamine-hydrolyzing], NAD+ synthase, NAD+ synthetase, NAD+ synthetase (glutamine-hydrolysing), NadE-679, NadE-738, NadE1, NADS, nic13, Nicotinamide adenine dinucleotide synthetase (glutamine), nicotinamide adenine dinucleotide synthetase enzyme, Nitrogen-regulatory protein, Qns1, Sporulation protein outB, Synthetase, nicotinamide adenine dinucleotide (glutamine)

ECTree

     6 Ligases

         6.3 Forming carbon-nitrogen bonds

             6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor

                6.3.5.1 NAD+ synthase (glutamine-hydrolysing)

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2	Activating Compound
29511	AA Sequence
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3	Cofactor
2	Crystallization (Commentary)
5	Disease/ Diagnostics
8	General Information
2	General Stability
4	IC50 Value
15	Inhibitors
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1	Ki Value [mM]
65	KM Value [mM]
12	Metals/Ions
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6	Natural Substrates/ Products (Substrates)
22	Organism
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21	Turnover Number [1/s]

Cloned

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Cloned on EC 6.3.5.1 - NAD+ synthase (glutamine-hydrolysing)

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

-

Mycobacterium tuberculosis

-

663373

expressed in Escherichia coli

Saccharomyces cerevisiae

-

674687

expressed in Escherichia coli as a His-tagged fusion protein

Acinetobacter baumannii

B0V8W9

715566

expression in Escherichia coli

Mycobacterium tuberculosis

-

705873

expression in Escherichia coli, with SUMO tag

Thermotoga maritima

-

702449

expression in Sf9 insect cells

Homo sapiens

-

660842

expression of His-tagged NAD+ synthase in Escherichia coli

Mycobacterium tuberculosis

-

651635

expression of Nadsyn1 and mutant enzyme C175S as His6-tagged proteins in COS-7 cells

Homo sapiens

Q6IA69

652364

gene nadE1, sequence comparisons, the nadE1 gene is linked to glnB encoding the signal transduction protein GlnB, recombinant expression of His-tagged enzyme in Escherichia coli strain BL21(DE3)

Herbaspirillum seropedicae

D8IS59

744183

most efficient expression of His-tagged NadE-738 and NadE-679 in Escherichia coli strain Origami

Mycobacterium tuberculosis

-

653750