6.3.4.23: formate-phosphoribosylaminoimidazolecarboxamide ligase

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For detailed information about formate-phosphoribosylaminoimidazolecarboxamide ligase, go to the full flat file.

Reaction

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

Synonyms

5-formaminoimidazole-4-carboxamide ribonucleotide synthetase, 5-formaminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate synthetase, PurP

ECTree

6 Ligases

6.3 Forming carbon-nitrogen bonds

6.3.4 Other carbon-nitrogen ligases

6.3.4.23 formate-phosphoribosylaminoimidazolecarboxamide ligase

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Results	in table
1154	AA Sequence
2	Cloned(Commentary)
1	Crystallization (Commentary)
3	Inhibitors
2	Metals/Ions
1	Natural Substrates/ Products (Substrates)
2	Organism
6	Pathway
2	pH Optimum
1	pH Range
2	Purification (Commentary)
1	Reaction
2	Reference
1	Specific Activity [micromol/min/mg]
4	Substrates and Products (Substrate)
4	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Stability [°C]

Reference

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Reference on EC 6.3.4.23 - formate-phosphoribosylaminoimidazolecarboxamide ligase

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721607

Zhang, Y.; White, R.H.; Ealick, S.E.

Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii

Biochemistry

205-217

2008

Methanocaldococcus jannaschii (Q57600), Methanocaldococcus jannaschii

18069798

722644

Ownby, K., Xu, H. and White, R.H.

A Methanocaldococcus jannaschii archaeal signature gene encodes for a 5-formaminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate synthetase. A new enzyme in purine biosynthesis

J. Biol. Chem.

280

10881-10887

2005

Methanocaldococcus jannaschii (Q57600), Methanocaldococcus jannaschii

15623504