6.3.4.23: formate-phosphoribosylaminoimidazolecarboxamide ligase

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Reaction

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

Synonyms

5-formaminoimidazole-4-carboxamide ribonucleotide synthetase, 5-formaminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate synthetase, PurP

ECTree

6 Ligases

6.3 Forming carbon-nitrogen bonds

6.3.4 Other carbon-nitrogen ligases

6.3.4.23 formate-phosphoribosylaminoimidazolecarboxamide ligase

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Natural Substrates Products on EC 6.3.4.23 - formate-phosphoribosylaminoimidazolecarboxamide ligase

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ATP + formate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

ADP + phosphate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

Methanocaldococcus jannaschii

Q57600

catalyses a step in the synthesis of purine nucleotides

722644