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6.3.4.20: 7-cyano-7-deazaguanine synthase

This is an abbreviated version!
For detailed information about 7-cyano-7-deazaguanine synthase, go to the full flat file.

Reaction

7-carboxy-7-carbaguanine
+
NH3
+
ATP
=
7-cyano-7-carbaguanine
+
ADP
+
phosphate
+
H2O

Synonyms

7-cyano-7-carbaguanine synthase, preQ0 synthase, queC

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.4 Other carbon-nitrogen ligases
                6.3.4.20 7-cyano-7-deazaguanine synthase

Subunits

Subunits on EC 6.3.4.20 - 7-cyano-7-deazaguanine synthase

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SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
dimer or tetramer
the biologically relevant unit is likely to be a QueC homodimer, crystal structure. Monomer structure, overview. The Rossmann fold of the N-terminal part of QueC, in combination with the C-terminal zinc-binding motif, forms a cavity in QueC of substantial size, which is likely to be the location of substrate binding