6.3.3.1: phosphoribosylformylglycinamidine cyclo-ligase

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Reaction

Synonyms

5'-Aminoimidazole ribonucleotide synthetase, 5'-Phosphoribosyl-5-aminoimidazole synthetase, AIR synthase, AIR synthetase, AIRS, aminoimidazole ribonucleotide synthetase, phosphoribosyl aminoimidazole synthetase, Phosphoribosyl-aminoimidazole synthetase, Phosphoribosylaminoimidazole synthetase, PurM, Synthetase, phosphoribosylaminoimidazole

ECTree

     6 Ligases

         6.3 Forming carbon-nitrogen bonds

             6.3.3 Cyclo-ligases

                6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase

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Results	in table
41398	AA Sequence
1	CAS Registry Number
9	Cloned(Commentary)
1	Crystallization (Commentary)
2	Disease/ Diagnostics
6	Inhibitors
1	Ki Value [mM]
13	KM Value [mM]
4	Localization
10	Metals/Ions
14	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
21	Organism
8	Pathway
34	PDB ID
2	pH Optimum
1	pH Range
5	Protein Variants
11	Purification (Commentary)
5	Reaction
1	Reaction Type
21	Reference
7	Source Tissue
3	Specific Activity [micromol/min/mg]
1	Storage Stability
27	Substrates and Products (Substrate)
7	Subunits
18	Synonyms
1	Systematic Name

Disease

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Disease on EC 6.3.3.1 - phosphoribosylformylglycinamidine cyclo-ligase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Lymphoma

Mammalian glycinamide ribonucleotide transformylase. Kinetic mechanism and associated de novo purine biosynthetic activities.

2925682

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