6.3.3.1: phosphoribosylformylglycinamidine cyclo-ligase

This is an abbreviated version!
For detailed information about phosphoribosylformylglycinamidine cyclo-ligase, go to the full flat file.

Word Map on EC 6.3.3.1

6.3.3.1

purine

transformylase

glycinamide

trifunctional

phosphoribosylglycinamide

formyltransferase

monofunctional

amidotransferase

formylglycinamide

2.1.2.2

cowpea

purl

phosphoribosylamine

unguiculata

Reaction

2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine

5-amino-1-(5-phospho-D-ribosyl)imidazole

Synonyms

5'-Aminoimidazole ribonucleotide synthetase, 5'-Phosphoribosyl-5-aminoimidazole synthetase, AIR synthase, AIR synthetase, AIRS, aminoimidazole ribonucleotide synthetase, phosphoribosyl aminoimidazole synthetase, Phosphoribosyl-aminoimidazole synthetase, Phosphoribosylaminoimidazole synthetase, PurM, Synthetase, phosphoribosylaminoimidazole

ECTree

6 Ligases

6.3 Forming carbon-nitrogen bonds

6.3.3 Cyclo-ligases

6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase

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Results	in table
41398	AA Sequence
1	CAS Registry Number
9	Cloned(Commentary)
1	Crystallization (Commentary)
2	Disease/ Diagnostics
6	Inhibitors
1	Ki Value [mM]
13	KM Value [mM]
4	Localization
10	Metals/Ions
14	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
21	Organism
8	Pathway
34	PDB ID
2	pH Optimum
1	pH Range
5	Protein Variants
11	Purification (Commentary)
5	Reaction
1	Reaction Type
21	Reference
7	Source Tissue
3	Specific Activity [micromol/min/mg]
1	Storage Stability
27	Substrates and Products (Substrate)
7	Subunits
18	Synonyms
1	Systematic Name

Purification

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Purification on EC 6.3.3.1 - phosphoribosylformylglycinamidine cyclo-ligase

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2 entries

bifunctional enzyme with AIR synthetase activity and phosphoribosyl-glycinamide synthetase activity

2 entries

copurification of AIR synthetase, glycinamide ribonucleotide synthetase, and glycinamide ribonucleotide transformylase

Homo sapiens

1310

purification of a histidine-tagged enzyme by nickel-affinity column chromatography

Salmonella enterica

P74883

651681

purification of a histidine-tagged recombinant enzyme by affinity chromatography

Vigna unguiculata

P52424

653485

purification of wild type and recombinant enzymes using C8-linked ATP affinity column

Escherichia coli

P08178

649909

trifunctional enzyme with AIR synthetase activity, phosphoribosylglycinamide synthetase activity, and phosphoribosylglycinamide transformylase activity

Gallus gallus

1309, 1312

using a recombinant histidine-tagged AIRS:cyanogen bromide Sepharose affinity resin

Vigna unguiculata

653535