6.2.1.40: 4-hydroxybutyrate-CoA ligase (AMP-forming)

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For detailed information about 4-hydroxybutyrate-CoA ligase (AMP-forming), go to the full flat file.

4-hydroxybutyrate-CoA ligase (AMP forming), 4-hydroxybutyrate-CoA synthetase, Msed_0394, Msed_0406, Msed_1353, Tneu_0420

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Results	in table
59	AA Sequence
4	Cloned(Commentary)
2	Expression
8	General Information
4	kcat/KM [mM/s]
5	KM Value [mM]
3	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
16	Organism
6	Pathway
3	pH Optimum
2	Protein Variants
3	Purification (Commentary)
1	Reaction
10	Reference
12	Source Tissue
4	Specific Activity [micromol/min/mg]
23	Substrates and Products (Substrate)
6	Subunits
18	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
4	Turnover Number [1/s]

Specific Activity on EC 6.2.1.40 - 4-hydroxybutyrate-CoA ligase (AMP-forming)

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0.22

substrate: 4-hydroxybutanoate, pH 7.9, 75°C

1.6

pH 7.8, 85°C

1.7

substrate: 4-hydroxybutanoate, pH 7.9, 75°C

2.3

substrate: 4-hydroxybutanoate, pH 7.9, 75°C, mutant enzyme W424G