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6.2.1.10: carboxylic acid-CoA ligase (GDP-forming)

This is an abbreviated version!
For detailed information about carboxylic acid-CoA ligase (GDP-forming), go to the full flat file.

Reaction

GTP
+
Octanoate
+
CoA
=
GDP
+
phosphate
+
octanoyl-CoA

Synonyms

Acid-CoA ligase (GDP), Acid:CoA ligase (GDP), Acyl coenzyme A synthetase (GDP-forming), Acyl-CoA synthetase (GDP-forming), GTP-dependent acyl-CoA synthetase, Synthetase, acyl coenzyme A (guanosine diphosphate-forming)

ECTree

     6 Ligases
         6.2 Forming carbon-sulfur bonds
             6.2.1 Acid-thiol ligases
                6.2.1.10 carboxylic acid-CoA ligase (GDP-forming)

Natural Substrates Products

Natural Substrates Products on EC 6.2.1.10 - carboxylic acid-CoA ligase (GDP-forming)

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
-
-
enzyme does not play an important role in the activation of fatty acids by uncoupled mitochondria
-
-
?