5.5.1.17: (S)-beta-macrocarpene synthase

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For detailed information about (S)-beta-macrocarpene synthase, go to the full flat file.

Reaction

Synonyms

terpene synthase 11, terpene synthase 6, TPS11, TPS6

ECTree

     5 Isomerases

         5.5 Intramolecular lyases

             5.5.1 Intramolecular lyases (only sub-subclass identified to date)

                5.5.1.17 (S)-beta-macrocarpene synthase

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Results	in table
2	AA Sequence
2	Cloned(Commentary)
2	Expression
1	General Information
1	KM Value [mM]
1	Localization
5	Metals/Ions
3	Natural Substrates/ Products (Substrates)
6	Organism
2	Pathway
3	pH Optimum
1	pH Range
3	Protein Variants
2	Purification (Commentary)
1	Reaction
2	Reference
4	Source Tissue
8	Substrates and Products (Substrate)
6	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Engineering

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Engineering on EC 5.5.1.17 - (S)-beta-macrocarpene synthase

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PROTEIN VARIANTS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

D526N

2 entries

Y522F

Zea mays

Q1EG72, Q5GJ60

the mutation strongly reduces the rate of reprotonation of (S)-beta-bisabolene

704432

D526N

Zea mays

Q1EG72, Q5GJ60

inactive

704432

D526N

Zea mays

Q1EG72, Q5GJ60

mutation inactivates the enzyme completely

704432