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5.4.99.32: protostadienol synthase

This is an abbreviated version!
For detailed information about protostadienol synthase, go to the full flat file.

Reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene
=
(17Z)-protosta-17(20),24-dien-3beta-ol

Synonyms

OSC3, OSPC, oxidosqualene:protostadienol cyclase, PdsA

ECTree

     5 Isomerases
         5.4 Intramolecular transferases
             5.4.99 Transferring other groups
                5.4.99.32 protostadienol synthase

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Resultsin table
4AA Sequence
1Cloned(Commentary)
1Localization
1Molecular Weight [Da]
13Organism
1Pathway
1Protein Variants
1Reaction
3Reference
3Substrates and Products (Substrate)
6Synonyms
1Systematic Name

Engineering

Engineering on EC 5.4.99.32 - protostadienol synthase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
-
an OSPC mutant in which the C-terminal residues 702APPGGMR708 are replaced with 702NKSCAIS708, no longer produces the protostadienol, but instead efficiently produces a 1:1 mixture of lanosterol and parkeol (oxidosqualene:lanosterol cyclase activity)