5.4.2.4: Bisphosphoglycerate mutase
This is an abbreviated version!
For detailed information about Bisphosphoglycerate mutase, go to the full flat file.
Word Map on EC 5.4.2.4
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5.4.2.4
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phosphofructokinase
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monophosphoglycerates
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1,3-bisphosphoglycerate
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erythrocytosis
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hemolysate
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erythrocyte-specific
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2-phosphoglycolate
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medicine
- 5.4.2.4
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phosphofructokinase
-
monophosphoglycerates
- 1,3-bisphosphoglycerate
- erythrocytosis
-
hemolysate
-
erythrocyte-specific
- 2-phosphoglycolate
- medicine
Reaction
Synonyms
2,3 bisphosphoglycerate mutase, 2,3-Bisphosphoglycerate mutase, 2,3-bisphosphoglycerate mutase, erythrocyte, 2,3-bisphosphoglycerate synthase, 2,3-Diphosphoglycerate mutase, 2,3-Diphosphoglycerate synthase, 2,3-Diphosphoglyceromutase, Biphosphoglycerate synthase, bisphosphoglycerate mutase, Bisphosphoglyceromutase, BPG synthase, BPG-dependent PGAM, BPGAM, BPGM, Diphosphoglycerate mutase, Diphosphoglyceric mutase, Diphosphoglyceromutase, DPGM, EC 2.7.5.4, Glycerate phosphomutase, Phosphomutase, glycerate (phosphoglycerate cofactor)
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Reference
Reference on EC 5.4.2.4 - Bisphosphoglycerate mutase
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Rose, Z.B.
The enzymology of 2,3-bisphosphoglycerate
Adv. Enzymol. Relat. Areas Mol. Biol.
51
211-253
1980
Homo sapiens
Ikura, K.; Narita, H.; Sasaki, R.; Chiba, H.
Immunochemical and enzymatic properties of bisphosphoglyceromutase/phosphatase and phosphoglyceromutase from human erythrocytes
Eur. J. Biochem.
89
23-31
1978
Homo sapiens
Hass, L.F.; Sheibley, R.H.; Kappel, W.K.; Miller, K.B.
A comparison of some of the physical and chemical properties of the phosphoglycerate mutases from human erythrocytes
Biochem. Biophys. Res. Commun.
72
976-983
1976
Homo sapiens
Sasaki, R.; Utsumi, S.; Sugimoto, E.; Chiba, H.
Subunit structure and multifunctional properties of yeast phosphoglyceromutase
Eur. J. Biochem.
66
523-533
1976
Saccharomyces cerevisiae
Ravel, P.; Craescus, C.T.; Arous, N.; Rosa, J.; Garel, M.C.
Critical Role of Human bisphosphoglycerate mutase Cys22 in the phosphatase activator-binding site
J. Biol. Chem.
272
14045-14050
1997
Homo sapiens
Calcin, M.C.; Blouquit, Y.; Garel, M.C.; Cohen-Solal, M.; Rosa, J.; Rosa, R.
Human bisphosphogycerate mutase expressed in E. coli: purification, characterization and structure studies
Biochimie
72
337-343
1990
Homo sapiens
Garel, M.C.; Lemarchandel, M.O.; Prehu, M.O.; Calvin, M.C.; Arous, N.; Rosa, R.; Rosa, J.
Natural and artificial mutants of the human 2,3-bisphosphoglycerate as a tool for the evaluation of structure-function relationship
Biomed. Biochim. Acta
49
166-171
1990
Homo sapiens
-
Garel, M.C.; Joulin, V.; Le Boulch, P.; Calvin, M.C.; Prehu, M.O.; Arous, N.; Longin, R.; Rosa, R.; Rosa, J.; Cohen-Solal, M.
Human bisphosphglycerate mutase. Expression in Escherichia coli and use of site-directed mutagenesis in the evaluation of the role of the carboxyl-terminal region in the enzymatic mechanism
J. Biol. Chem.
264
18966-18972
1989
Homo sapiens
Rosa, R.; Blouquit, Y.; Calvin, M.C.; Prome, D.; Prome, J.C.; Rosa, J.
Isolation, characterization, and structure of a mutant 89 ARG->Cys bisphosphoglycerate mutase. Implication of the active site in the mutation
J. Biol. Chem.
264
7837-7843
1989
Homo sapiens
Rosa, R.; Calvin, M.C.
Comparative effects of two sulfhydryl reagents on the activities of a multifunctional red cell enzyme: bisphosphoglycerate mutase
Biochem. Biophys. Res. Commun.
153
945-951
1988
Homo sapiens
Cherfils, J.; Rosa, R.; Garel, M.C.; Calvin, M.C.; Rosa, J.; Janin, J.
Crystallization and preliminary X-ray diffraction studies of the human erythrocyte bisphosphoglycerate mutase
J. Mol. Biol.
20
269-270
1991
Homo sapiens
Rose, Z.B.; Whalen, R.G.
The phosphorylation of diphosphoglycerate mutase
J. Biol. Chem.
248
1513-1519
1973
Homo sapiens
Rose, Z.B.
Effects of salt and pH on the rate of erythrocyte diphosphoglycerate mutase
Arch. Biochem. Biophys.
158
903-910
1973
Homo sapiens
McPherson, A.
Crystallization of proteins from polyethylene glycol
J. Biol. Chem.
251
6300-6303
1976
Homo sapiens
Harkness, D.R.; Isaacks, R.E.; Roth, S.C.
Purification and properties of 2,3-bisphosphoglycerate phosphatase-mutase from erythrocytes of day-old chicks
Eur. J. Biochem.
78
343-351
1977
Gallus gallus
Sasaki, R.; Ikura, K.; Sugimoto, E.; Chiba, H.
Purification of bisphosphoglyceromutase, 2,3-bisphosphoglycerate phosphatase and phosphoglyceromutase from human erthrocytes. Three enzyme activities in one protein
Eur. J. Biochem.
50
581-593
1975
Homo sapiens
Rose, Z.B.
2,3-Diphosphoglycerate mutase from human erythrocytes
Methods Enzymol.
42C
450-454
1975
Homo sapiens
Kappel, W.K.; Hass, L.F.
The isolation and partial characterization of diphosphoglycerate mutase from human erythrocytes
Biochemistry
15
290-295
1976
Homo sapiens
Ikura, K.; Sasaki, R.; Narita, H.; Sugimoto, E.; Chiba, H.
Multifunctional enzyme, bisphosphoglyceromutase/2,3-bisphosphoglycerate phosphatase/phosphoglyceromutase, from human erythrocytes. Evidence for a common active site
Eur. J. Biochem.
66
515-522
1976
Homo sapiens
Rose, Z.B.; Dube, S.
The purification and kinetic properties of bisphosphoglycerate synthase from horse red blood cells
Arch. Biochem. Biophys.
177
284-292
1976
Equus caballus
Utsumi, S.; Yano, Y.; Sasaki, R.; Chiba, H.
Interaction of yeast phosphoglyceromutase with nucleotides
Agric. Biol. Chem.
41
1852-1862
1977
Saccharomyces cerevisiae
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Rosa, R.; Prehu, M.O.; Albrecht-Ellmer, K.; Calvin, M.C.
Partial characterization of the inactive mutant form of human red cell bisphosphoglyceromutase and comparison with an alkylated form
Biochim. Biophys. Acta
742
243-249
1983
Homo sapiens
Joulin, V.; Peduzzi, J.; Romeo, P.H.; Rosa, R.; Valentin, C.; Dubart, A.; Lapeyre, B.; Blouquit, Y.; Garel, M.C.; Goossens, M.; Rosa, J.; Cohen-Solal, M.
Molecular cloning and sequencing of the human erythrocyte 2,3-bisphosphoglycerate mutase cDNA: revised amino acid sequence
EMBO J.
5
2275-2283
1986
Homo sapiens
Fujita, T.; Suzuki, K.; Tada, T.; Yoshihara, Y.; Hamaoka, R.; Uchida, K.; Matuo, Y.; Sasaki, T.; Hanafusa, T.; Taniguchi, N.
Human erythrocyte bisphosphoglycerate mutase: inactivation by glycation in vivo and in vitro
J. Biochem.
124
1237-1244
1998
Homo sapiens
Hoyer, J.D.; Allen, S.L.; Beutler, E.; Kubik, K.; West, C.; Fairbanks, V.F.
Erythrocytosis due to bisphosphoglycerate mutase deficiency with concurrent glucose-6-phosphate dehydrogenase (G-6-PD) deficiency
Am. J. Hematol.
75
205-208
2004
Homo sapiens
Wang, Y.; Wei, Z.; Bian, Q.; Cheng, Z.; Wan, M.; Liu, L.; Gong, W.
Crystal structure of human bisphosphoglycerate mutase
J. Biol. Chem.
279
39132-39138
2004
Homo sapiens (P07738), Homo sapiens
Wang, Y.; Liu, L.; Wei, Z.; Cheng, Z.; Lin, Y.; Gong, W.
Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase
J. Biol. Chem.
281
39642-39648
2006
Homo sapiens (P07738), Homo sapiens
Gu, M.; Pritlove, D.C.; Boyd, C.A.; Vatish, M.
Placental expression of 2,3 bisphosphoglycerate mutase in IGF-II knock out mouse: correlation ofcirculating maternal 2,3 bisphosphoglycerate and fetal growth
Placenta
30
919-922
2009
Mus musculus
Patterson, A.; Price, N.C.; Nairn, J.
Unliganded structure of human bisphosphoglycerate mutase reveals side-chain movements induced by ligand binding
Acta Crystallogr. Sect. F
66
1415-1420
2010
Homo sapiens (P07738), Homo sapiens
Bertrand, R.
Nitric oxide-mediated suppression of 2,3-bisphosphoglycerate synthesis: therapeutic relevance for environmental hypoxia and sickle cell disease
Med. Hypotheses
79
315-318
2012
Homo sapiens
Chu, W.T.; Zheng, Q.C.; Zhang, H.X.
Insights into the phosphatase and the synthase activities of human bisphosphoglycerate mutase: a quantum mechanics/molecular mechanics simulation
Phys. Chem. Chem. Phys.
16
3946-3954
2014
Homo sapiens
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