5.4.2.11: phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)

This is an abbreviated version!
For detailed information about phosphoglycerate mutase (2,3-diphosphoglycerate-dependent), go to the full flat file.

Word Map on EC 5.4.2.11

5.4.2.11

enolase

aldolase

isozyme

2-phosphoglycerate

glyceraldehyde-3-phosphate

glycogen

creatine

mutases

triosephosphate

phosphofructokinase

muscle-specific

cofactor-independent

cramp

myoglobinuria

triose

bb

fructose-2,6-bisphosphatase

phosphohistidine

tpi

warburg

phosphoenzyme

fructose-bisphosphate

aldoa

brugia

malayi

medicine

biofuel production

drug development

Reaction

2-phospho-D-glycerate

=

3-phospho-D-glycerate

Synonyms

2,3-bisphosphoglycerate-dependent PGAM, 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, alpha-PGAM, B-type PGM, cofactor-dependent phosphoglycerate mutase, dPGAM, DPGM, dPGM-B, EC 2.7.5.3, EC 3.1.3.13, EC 5.4.2.1, EntD, PGAM, PGAM1, PGAM2, PGM, phosphoglycerate mutase, phosphoglycerate mutase 1, phosphoglycerate mutase type B, Phosphoglyceromutase, Rv3214, ScPGM, SSO2236, Sts-1

ECTree

5.4 Intramolecular transferases

5.4.2 Phosphotransferases (phosphomutases)

5.4.2.11 phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
30	Activating Compound
25222	AA Sequence
10	Application
18	Cloned(Commentary)
2	Cofactor
12	Crystallization (Commentary)
676	Disease/ Diagnostics
2	Expression
9	General Information
5	General Stability
68	IC50 Value
96	Inhibitors
12	Ki Value [mM]
37	KM Value [mM]
6	Localization
25	Molecular Weight [Da]
22	Natural Substrates/ Products (Substrates)
109	Organism
17	Pathway
29	PDB ID
6	pH Optimum
1	pH Range
3	pI Value
2	Posttranslational Modification
20	Protein Variants
28	Purification (Commentary)
11	Reaction
90	Reference
2	Renatured (Commentary)
87	Source Tissue
21	Specific Activity [micromol/min/mg]
4	Storage Stability
68	Substrates and Products (Substrate)
20	Subunits
58	Synonyms
1	Systematic Name
13	Temperature Stability [°C]
16	Turnover Number [1/s]

IC50 Value

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

IC50 Value on EC 5.4.2.11 - phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

back to the top

Go to IC50 Value Search

0.0019

1-phenyl-N-(1,2,8-trihydroxy-9-oxo-9H-xanthen-3-yl)methanesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0063

2,5-bis(trifluoromethyl)-N-(1,2,8-trihydroxy-9-oxo-9Hxanthen-3-yl)benzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0102

2,6-dichloro-N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0058

3-(trifluoromethoxy)-N-(1,2,8-trihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0064

3-chloro-N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-2-fluorobenzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0021

3-cyano-N-(1,2,8-trihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.02

3-cyano-N-(1-hydroxy-2,8-dimethoxy-9-oxo-9H-xanthen-3-yl)benzene-1-sulfonamide

Homo sapiens

IC50 value far above 0.02 mM, at pH 8.0 and 25°C

0.001

4-(piperidin-1-yl)-N-(1,2,8-trihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0027

4-(pyrrolidin-1-yl)-N-(1,2,8-trihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0026

4-(tert-butyl)-N-(1,2,8-trihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0084

4-(tert-butyl)-N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.02

4-(tert-butyl)-N-(1-hydroxy-2,8-dimethoxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

IC50 value far above 0.02 mM, at pH 8.0 and 25°C

0.0035

4-(trifluoromethyl)-N-(1,2,8-trihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0029

4-bromo-N-(1,2,8-trihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.02

4-bromo-N-(1-hydroxy-2,8-dimethoxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

IC50 value far above 0.02 mM, at pH 8.0 and 25°C

0.0036

4-chloro-N-(1,2,8-trihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.02

4-chloro-N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

IC50 value above 0.02 mM, at pH 8.0 and 25°C

0.02

4-chloro-N-(1-hydroxy-2,8-dimethoxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

IC50 value far above 0.02 mM, at pH 8.0 and 25°C

0.0042

4-cyano-N-(1,2,8-trihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.02

4-cyano-N-(1-hydroxy-2,8-dimethoxy-9-oxo-9H-xanthen-3-yl)benzene-1-sulfonamide

Homo sapiens

IC50 value far above 0.02 mM, at pH 8.0 and 25°C

0.0005

4-cyclohexyl-N-(1,2,8-trihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0059

4-cyclohexyl-N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.02

4-cyclohexyl-N-(1-hydroxy-2,8-dimethoxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

IC50 value far above 0.02 mM, at pH 8.0 and 25°C

0.0055

4-fluoro-N-(1,2,8-trihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.02

4-fluoro-N-(1-hydroxy-2,8-dimethoxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

IC50 value far above 0.02 mM, at pH 8.0 and 25°C

0.0019

4-iodo-N-(1,2,8-trihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0072

4-methyl-N-(1,2,8-trihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0027

6-([1,1'-biphenyl]-4-sulfonamido)-8-hydroxy-9-oxo-9H-xanthen-2-yl acetate

Homo sapiens

at pH 8.0 and 25°C

0.00049

epigallocatechin gallate

Homo sapiens

at pH 8.0 and 25°C

0.000193

gemcitabine

Homo sapiens

at pH 8.0 and 25°C

0.033

MJE3

Homo sapiens

at pH 8.0 and 25°C

0.0012

N-(1,2,8-trihydroxy-9-oxo-9H-xanthen-3-yl)-[1,10-biphenyl]-4-sulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0028

N-(1,2,8-trihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0017

N-(1,2,8-trihydroxy-9-oxo-9H-xanthen-3-yl)naphthalene-1-sulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0016

N-(1,2,8-trihydroxy-9-oxo-9H-xanthen-3-yl)naphthalene-2-sulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0064

N-(1,7-dihydroxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.02

N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-1-phenylmethanesulfonamide

Homo sapiens

IC50 value above 0.02 mM, at pH 8.0 and 25°C

0.02

N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-2-fluorobenzenesulfonamide

Homo sapiens

IC50 value above 0.02 mM, at pH 8.0 and 25°C

0.0132

N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-3,5-difluorobenzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.02

N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-4-fluorobenzenesulfonamide

Homo sapiens

IC50 value above 0.02 mM, at pH 8.0 and 25°C

0.0101

N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-4-iodobenzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.02

N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-4-methylbenzenesulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0055

N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.02

N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

IC50 value above 0.02 mM, at pH 8.0 and 25°C

0.006

N-(1,8-dihydroxy-9-oxo-9H-xanthen-3-yl)naphthalene-1-sulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.02

N-(1-hydroxy-2,8-dimethoxy-9-oxo-9H-xanthen-3-yl)-1-phenylmethanesulfonamide

Homo sapiens

IC50 value far above 0.02 mM, at pH 8.0 and 25°C

0.02

N-(1-hydroxy-2,8-dimethoxy-9-oxo-9H-xanthen-3-yl)-2,5-bis(trifluoromethyl)benzenesulfonamide

Homo sapiens

IC50 value far above 0.02 mM, at pH 8.0 and 25°C

0.02

N-(1-hydroxy-2,8-dimethoxy-9-oxo-9H-xanthen-3-yl)-3-(trifluoromethoxy)benzenesulfonamide

Homo sapiens

IC50 value far above 0.02 mM, at pH 8.0 and 25°C

0.02

N-(1-hydroxy-2,8-dimethoxy-9-oxo-9H-xanthen-3-yl)-4-(piperidin-1-yl)benzenesulfonamide

Homo sapiens

IC50 value far above 0.02 mM, at pH 8.0 and 25°C

0.02

N-(1-hydroxy-2,8-dimethoxy-9-oxo-9H-xanthen-3-yl)-4-(pyrrolidin-1-yl)benzenesulfonamide

Homo sapiens

IC50 value far above 0.02 mM, at pH 8.0 and 25°C

0.02

N-(1-hydroxy-2,8-dimethoxy-9-oxo-9H-xanthen-3-yl)-4-(trifluoromethyl)benzenesulfonamide

Homo sapiens

IC50 value far above 0.02 mM, at pH 8.0 and 25°C

0.02

N-(1-hydroxy-2,8-dimethoxy-9-oxo-9H-xanthen-3-yl)-4-iodobenzenesulfonamide

Homo sapiens

IC50 value far above 0.02 mM, at pH 8.0 and 25°C

0.02

N-(1-hydroxy-2,8-dimethoxy-9-oxo-9H-xanthen-3-yl)-4-methylbenzenesulfonamide

Homo sapiens

IC50 value far above 0.02 mM, at pH 8.0 and 25°C

0.02

N-(1-hydroxy-2,8-dimethoxy-9-oxo-9H-xanthen-3-yl)-[1,10-biphenyl]-4-sulfonamide

Homo sapiens

IC50 value far above 0.02 mM, at pH 8.0 and 25°C

0.02

N-(1-hydroxy-2,8-dimethoxy-9-oxo-9H-xanthen-3-yl)benzenesulfonamide

Homo sapiens

IC50 value far above 0.02 mM, at pH 8.0 and 25°C

0.02

N-(1-hydroxy-2,8-dimethoxy-9-oxo-9H-xanthen-3-yl)naphthalene-1-sulfonamide

Homo sapiens

IC50 value far above 0.02 mM, at pH 8.0 and 25°C

0.02

N-(1-hydroxy-2,8-dimethoxy-9-oxo-9H-xanthen-3-yl)naphthalene-2-sulfonamide

Homo sapiens

IC50 value far above 0.02 mM, at pH 8.0 and 25°C

0.0065

N-(1-hydroxy-5-methoxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0086

N-(1-hydroxy-5-methyl-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0046

N-(1-hydroxy-7-methoxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.008

N-(1-hydroxy-7-methyl-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0021

N-(1-hydroxy-7-nitro-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0143

N-(1-hydroxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0035

N-(7-chloro-1-hydroxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.0137

N-(7-fluoro-1-hydroxy-9-oxo-9H-xanthen-3-yl)-[1,1'-biphenyl]-4-sulfonamide

Homo sapiens

at pH 8.0 and 25°C

0.013 - 0.0131

PGMI-004A

show

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)