5.4.2.11: phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)
This is an abbreviated version!
For detailed information about phosphoglycerate mutase (2,3-diphosphoglycerate-dependent), go to the full flat file.
Word Map on EC 5.4.2.11
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5.4.2.11
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enolase
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aldolase
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isozyme
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2-phosphoglycerate
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glyceraldehyde-3-phosphate
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glycogen
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creatine
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mutases
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triosephosphate
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phosphofructokinase
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muscle-specific
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cofactor-independent
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cramp
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myoglobinuria
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triose
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bb
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fructose-2,6-bisphosphatase
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phosphohistidine
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tpi
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warburg
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phosphoenzyme
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fructose-bisphosphate
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aldoa
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brugia
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malayi
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medicine
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biofuel production
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drug development
- 5.4.2.11
- enolase
- aldolase
- isozyme
- 2-phosphoglycerate
- glyceraldehyde-3-phosphate
- glycogen
- creatine
- mutases
-
triosephosphate
-
phosphofructokinase
-
muscle-specific
-
cofactor-independent
- cramp
- myoglobinuria
- triose
- bb
- fructose-2,6-bisphosphatase
-
phosphohistidine
- tpi
-
warburg
- phosphoenzyme
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fructose-bisphosphate
- aldoa
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brugia
- malayi
- medicine
- biofuel production
- drug development
Reaction
Synonyms
2,3-bisphosphoglycerate-dependent PGAM, 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, alpha-PGAM, B-type PGM, cofactor-dependent phosphoglycerate mutase, dPGAM, DPGM, dPGM-B, EC 2.7.5.3, EC 3.1.3.13, EC 5.4.2.1, EntD, PGAM, PGAM1, PGAM2, PGM, phosphoglycerate mutase, phosphoglycerate mutase 1, phosphoglycerate mutase type B, Phosphoglyceromutase, Rv3214, ScPGM, SSO2236, Sts-1
ECTree
5.4.2.11 phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)Advanced search results
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General Information on EC 5.4.2.11 - phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)
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GENERAL INFORMATION 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
malfunction
enzyme knockdown significantly inhibits glioma cell proliferation, promotes glioma cell apoptosis, induces S phase cell cycle arrest and inhibits glioma cell migration and invasion in vitro
metabolism
physiological function
additional information
metabolism
the enzyme catalyzes the interconversion of 3-phosphoglycerate and 2-phosphoglycerate as a key step in the glycolytic pathway
metabolism
anaerobic fermentative metabolism of glycerol. Proteome analysis as well as enzyme assays performed in cell-free extracts demonstrate that glycerol is degraded via glyceraldehyde-3-phosphate, which is further metabolized through the lower part of glycolysis leading to formation of mainly ethanol and hydrogen
metabolism
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the enzyme catalyzes the interconversion of 3-phosphoglycerate and 2-phosphoglycerate as a key step in the glycolytic pathway
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physiological function
Brucellae are intracellular bacterial pathogens that cause Brucellosis. Earlier immune response plays an important role in the Brucella infection. The phosphoglyceromutase protein could induce Th1 and Th2-type immune responses in vivo and in vitro
physiological function
the enzyme is associated with the grade of glioma and is involved in the biological behavior of glioma cells
physiological function
Brucella abortus S2308
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Brucellae are intracellular bacterial pathogens that cause Brucellosis. Earlier immune response plays an important role in the Brucella infection. The phosphoglyceromutase protein could induce Th1 and Th2-type immune responses in vivo and in vitro
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additional information
active site residues are Thr21, Gly22, Tyr90, Lys98, Arg114 and Arg115
additional information
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active site residues are Thr21, Gly22, Tyr90, Lys98, Arg114 and Arg115
additional information
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active site residues are Thr21, Gly22, Tyr90, Lys98, Arg114 and Arg115
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