5.1.3.3: Aldose 1-epimerase

This is an abbreviated version!
For detailed information about Aldose 1-epimerase, go to the full flat file.

Reaction

Synonyms

aldose 1-epimerase, aldose 1-epimerase-like protein, aldose mutarotase, aldose-1-epimerase, aldose-l-epimerase, Epimerase, aldose-1, Gal10p, galactomutarotase, galactose mutarotase, galactose mutarotase/UDP-galactose 4-epimerase protein, GalM, Mutarotase, mutarotase YeaD, NbAELP, stYeaD, YeaD

ECTree

     5 Isomerases

         5.1 Racemases and epimerases

             5.1.3 Acting on carbohydrates and derivatives

                5.1.3.3 Aldose 1-epimerase

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Results	in table
23636	AA Sequence
4	Application
2	CAS Registry Number
19	Cloned(Commentary)
1	Cofactor
10	Crystallization (Commentary)
9	Disease/ Diagnostics
1	Expression
10	General Information
2	General Stability
87	Inhibitors
84	KM Value [mM]
8	Localization
1	Metals/Ions
44	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
78	Organism
9	Pathway
59	PDB ID
9	pH Optimum
2	pH Range
6	pH Stability
3	pI Value
14	Protein Variants
17	Purification (Commentary)
9	Reaction
2	Reaction Type
73	Reference
36	Source Tissue
16	Specific Activity [micromol/min/mg]
1	Storage Stability
126	Substrates and Products (Substrate)
23	Subunits
28	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
1	Temperature Range [°C]
9	Temperature Stability [°C]
33	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 5.1.3.3 - Aldose 1-epimerase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

alpha-D-galactose

beta-D-galactose

3 entries

alpha-D-glucose

beta-D-glucose

Bos taurus

-

-

728838

-

-

?

additional information

?

-

4 entries

alpha-D-galactose

beta-D-galactose

Saccharomyces cerevisiae

-

the two enzyme activities, galactose mutarotase and UDP-galactose 4-epimerase, are required for the Leloir pathway of D-galactose catabolism, they are contained within a single protein–Gal10p

673761

-

-

?

alpha-D-galactose

beta-D-galactose

Yersinia pestis

-

-

728233

-

-

r

alpha-D-galactose

beta-D-galactose

Yersinia pestis KIM D27

-

-

728233

-

-

r

additional information

?

-

Homo sapiens

Q96C23

key enzyme of carbohydrate metabolism catalysing the interconversion of the alpha-anomer and beta-anomer of hexose sugars such as glucose and galactose

651324

-

651324

?

additional information

?

-

Homo sapiens

-

key enzyme of carbohydrate metabolism catalysing the interconversion of the alpha-anomer and beta-anomer of hexose sugars such as glucose and galactose

651324

-

651324

?

additional information

?

-

Rattus norvegicus

-

may be involved in the metabolism of D-glucose in nuclei

2373

-

-

?

additional information

?

-

Rhizopus stolonifer

-

glucose is most probably not the best physiological substrate of the enzyme

661785

-

-

?