4.4.1.9: L-3-cyanoalanine synthase

This is an abbreviated version!
For detailed information about L-3-cyanoalanine synthase, go to the full flat file.

Word Map on EC 4.4.1.9

4.4.1.9

anhydrases

beta-carbonic

4.2.99.8

o-acetylserine

beta-class

5'-phosphosulfate

2.7.7.4

agriculture

1.8.7.1

alpha-cas

gamma-cas

Reaction

Synonyms

AtcysC1, beta-CAS, beta-cyano-L-alanine synthase, beta-cyanoalanine synthase, beta-cyanoalanine synthetase, BsaS, Bsas3, BsasA, BsasB, CAS, CAS1, CAS2, cyanoalanine synthase, CYS-C1, L-cysteine hydrogen-sulfide-lyase, L-cysteine: hydrogen sulphide lyase, O-acetyl-L-serine sulfhydrylase, PCAS-1, PCAS-2, synthase,.beta.-cyanoalanine, Tu-CAS

ECTree

4 Lyases

4.4 Carbon-sulfur lyases

4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date)

4.4.1.9 L-3-cyanoalanine synthase

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Results	in table
18	Activating Compound
50	AA Sequence
3	Application
1	CAS Registry Number
12	Cloned(Commentary)
18	Cofactor
1	Crystallization (Commentary)
11	General Information
2	IC50 Value
40	Inhibitors
2	kcat/KM [mM/s]
16	Ki Value [mM]
89	KM Value [mM]
22	Localization
3	Metals/Ions
25	Molecular Weight [Da]
35	Natural Substrates/ Products (Substrates)
82	Organism
5	Pathway
22	pH Optimum
6	pH Range
1	pH Stability
1	pI Value
1	Protein Variants
24	Purification (Commentary)
2	Reaction
2	Reaction Type
78	Reference
68	Source Tissue
36	Specific Activity [micromol/min/mg]
3	Storage Stability
120	Substrates and Products (Substrate)
15	Subunits
48	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Temperature Stability [°C]
14	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 4.4.1.9 - L-3-cyanoalanine synthase

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chloroalanine + sulfide

L-cysteine + Cl-

Spinacia oleracea

652652

L-cysteine + HCN

9 entries

L-cysteine + HCN

H2S + L-3-cyanoalanine

Priestia megaterium

704926

L-cysteine + HCN

sulfide + L-3-cyanoalanine

10 entries

L-cysteine + hydrogen cyanide

hydrogen sulfide + L-3-cyanoalanine

5 entries

O-acetyl-L-serine + CN-

acetate + L-3-cyanoalanine

Geobacillus stearothermophilus

Q84IF9

652590

O-acetyl-L-serine + sulfide

L-cysteine + acetate

7 entries

additional information

Tetranychus urticae

T1KF23

the enzyme is also active with O-acetyl-L-serine, EC 2.5.1.47, but the L-3-cyanoalanine forming activity is highly preferred

729637