4.3.3.5: 4'-demethylrebeccamycin synthase

This is an abbreviated version!
For detailed information about 4'-demethylrebeccamycin synthase, go to the full flat file.

Reaction

Synonyms

ngt, RebG

ECTree

     4 Lyases

         4.3 Carbon-nitrogen lyases

             4.3.3 Amine-lyases

                4.3.3.5 4'-demethylrebeccamycin synthase

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Results	in table
188	AA Sequence
1	Cloned(Commentary)
1	General Information
4	Organism
4	Pathway
2	Protein Variants
1	Purification (Commentary)
1	Reaction
4	Reference
10	Substrates and Products (Substrate)
3	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 4.3.3.5 - 4'-demethylrebeccamycin synthase

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SYSTEMATIC NAME

IUBMB Comments

4'-demethylrebeccamycin D-glucose-lyase

This enzyme catalyses a step in the biosynthesis of rebeccamycin, an indolocarbazole alkaloid produced by the bacterium Lechevalieria aerocolonigenes. The enzyme is a glycosylase, and acts in the reverse direction to that shown. It has a wide substrate range, and was shown to glycosylate several substrates, including the staurosporine aglycone, EJG-III-108A, J-104303, 6-N-methyl-arcyriaflavin C and indolo-[2,3-a]-carbazole [1,2].