4.2.3.146: cyclooctat-9-en-7-ol synthase This is an abbreviated version! For detailed information about cyclooctat-9-en-7-ol synthase, go to the full flat file .
Word Map on EC 4.2.3.146
4.2.3.146
cyclization
multiscale
carbocation
synthases
hydride
diversified
exquisite
regiospecific
stereochemistry
macrocycle
carbon-carbon
stereochemical
terpenoids
snapshots
synthesis
Reaction
geranylgeranyl diphosphate +
H2O =
cyclooctat-9-en-7-ol +
diphosphate
Synonyms cetB2, CotB2, CYC, diterpene cyclooctatin synthase
ECTree
Systematic Name
Systematic Name on EC 4.2.3.146 - cyclooctat-9-en-7-ol synthase
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geranylgeranyl-diphosphate diphosphate-lyase (cyclooctat-9-en-7-ol-forming)
Requires Mg2+. Isolated from the bacterium Streptomyces melanosporofaciens, where it is part of the biosynthesis of cyclooctatin, a potent inhibitor of lysophospholipase.