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4.2.3.141: sclareol synthase

This is an abbreviated version!
For detailed information about sclareol synthase, go to the full flat file.

Reaction

(13E)-8alpha-hydroxylabd-13-en-15-yl diphosphate
+
H2O
=
sclareol
+
diphosphate

Synonyms

EC 3.1.7.4, sclareol synthase, SsSS

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.141 sclareol synthase

Systematic Name

Systematic Name on EC 4.2.3.141 - sclareol synthase

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SYSTEMATIC NAME
IUBMB Comments
(13E)-8alpha-hydroxylabd-13-en-15-yl-diphosphate-lyase (sclareol forming)
Isolated from the plant Salvia sclarea (clary sage). Originally thought to be synthesized in one step from geranylgeranyl diphosphate it is now known to require two enzymes, EC 4.2.1.133, copal-8-ol diphosphate synthase and EC 4.2.3.141, sclareol synthase. Sclareol is used in perfumery.