4.2.1.76: UDP-glucose 4,6-dehydratase

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For detailed information about UDP-glucose 4,6-dehydratase, go to the full flat file.

Reaction

Synonyms

bifunctional UDP-4-keto-6-deoxy-D-glucose epimerase/reductase, GAL102, RHM1, RHM2/MUM4, RHM3, UDP-D-glucose 4,6-dehydratase, UDP-D-glucose-4,6-hydrolyase, UDP-Glc 4,6-dehydratase, UDP-glucose-4,6-dehydratase, UG4,6-Dh, Ugd, UGER

ECTree

4 Lyases

4.2 Carbon-oxygen lyases

4.2.1 Hydro-lyases

4.2.1.76 UDP-glucose 4,6-dehydratase

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Results	in table
1	Activating Compound
25	AA Sequence
1	CAS Registry Number
6	Cloned(Commentary)
3	Cofactor
4	General Information
9	Inhibitors
3	KM Value [mM]
11	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
9	Organism
3	Pathway
6	pH Optimum
2	pH Range
5	Protein Variants
4	Purification (Commentary)
1	Reaction
1	Reaction Type
9	Reference
2	Source Tissue
2	Specific Activity [micromol/min/mg]
20	Substrates and Products (Substrate)
7	Subunits
21	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]
1	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 4.2.1.76 - UDP-glucose 4,6-dehydratase

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100000

Acanthamoeba polyphaga Mimivirus

UGD, gel filtration

716065

140000

2 entries

33000

Acanthamoeba polyphaga Mimivirus

x * 33000, UGER, SDS-PAGE

716065

37000

Acanthamoeba polyphaga Mimivirus

2 * 37000, UGD, SDS-PAGE

716065

39000

Acanthocystis turfacea chlorella virus 1

2 * 39000, UGD, SDS-PAGE

716065

47000

Acanthamoeba polyphaga Mimivirus

UGER, gel filtration

52000

3 * 52000, SDS-PAGE

52500

3 * 52500, SDS-PAGE

75000

Acanthocystis turfacea chlorella virus 1

UGD, gel filtration

716065

additional information

Arabidopsis thaliana

RHM2/MUM4 is a trifunctional enzyme with UDP-D-glucose 4,6-dehydratase, UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase, and UDP-4-keto-L-rhamnose 4-keto-reductase activities. The N-terminal region of RHM2 (RHM2-N: amino acids 1-370) has the first activity and the C-terminal region of RHM2 (RHM2-C: amino acids 371-667) has the two following activities

680873