4.2.1.19: imidazoleglycerol-phosphate dehydratase

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For detailed information about imidazoleglycerol-phosphate dehydratase, go to the full flat file.

Word Map on EC 4.2.1.19

4.2.1.19

herbicide

auxotrophs

3-amino-1,2,4-triazole

phosphonate

histidinol

Reaction

D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate

Synonyms

dehydratase, imidazoleglycerol phosphate, His3, HisB, HisN5B, IGP dehydratase, IGPD, imidazoleglycerol phosphate dehydratase, imidazoleglycerolphoshate dehydratase

ECTree

4 Lyases

4.2 Carbon-oxygen lyases

4.2.1 Hydro-lyases

4.2.1.19 imidazoleglycerol-phosphate dehydratase

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Results	in table
3	Activating Compound
34630	AA Sequence
1	CAS Registry Number
10	Cloned(Commentary)
7	Crystallization (Commentary)
4	General Stability
20	Inhibitors
4	Ki Value [mM]
9	KM Value [mM]
1	Localization
10	Metals/Ions
16	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
33	Organism
1	Oxidation Stability
6	Pathway
137	PDB ID
5	pH Optimum
2	pH Range
1	pH Stability
1	Protein Variants
11	Purification (Commentary)
4	Reaction
1	Reaction Type
33	Reference
6	Source Tissue
3	Specific Activity [micromol/min/mg]
33	Substrates and Products (Substrate)
10	Subunits
16	Synonyms
1	Systematic Name
2	Temperature Stability [°C]
1	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 4.2.1.19 - imidazoleglycerol-phosphate dehydratase

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21206

Triticum aestivum

24 * 21206, MALDI-TOF

5545

22000

Cryptococcus neoformans

x * 22000, calculation from nucleotide sequence

5541

22466

Trichoderma harzianum

x * 22466, calculation from nucleotide sequence

5539

23833

Saccharomyces cerevisiae

x * 23833, light scattering

5546

25000

Triticum aestivum

x * 25000, subunits not linked by disulfide bridges, SDS-PAGE

5540

260000

Salmonella enterica subsp. enterica serovar Typhimurium

bifunctional enzyme with EC 3.1.3.15, gel filtration

5531

290000

Saccharomyces cerevisiae

gel filtration

5534

300000

Saccharomyces cerevisiae

gel electrophoresis

5534

35000

Saccharomyces cerevisiae

x * 35000, SDS-PAGE

5534

46000

Salmonella enterica subsp. enterica serovar Typhimurium

x * 46000, bifunctional enzyme with EC 3.1.3.15, SDS-PAGE

5531

500000

Saccharomyces cerevisiae

polymeric enzyme in presence of Mn2+, gel filtration

5546

540000

Arabidopsis thaliana

gel filtration

5545

570000

Mycobacterium tuberculosis

gel filtration

600000

gel filtration

670000

gel electrophoresis

70000

Saccharomyces cerevisiae

trimeric enzyme in absence of Mn2+, gel filtration

5546