4.1.1.94: ethylmalonyl-CoA decarboxylase
This is an abbreviated version!
For detailed information about ethylmalonyl-CoA decarboxylase, go to the full flat file.
Word Map on EC 4.1.1.94
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4.1.1.94
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acetyl-coa
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aciduria
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branched-chain
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propionyl-coa
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ethylmalonic
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polyhydroxyalkanoates
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butyryl-coa
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proofreading
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itraq
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crotonyl-coa
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methyl-branched
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poly3-hydroxybutyrate-co-3-hydroxyhexanoate
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hydratase
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medicine
- 4.1.1.94
- acetyl-coa
-
aciduria
-
branched-chain
- propionyl-coa
-
ethylmalonic
- polyhydroxyalkanoates
- butyryl-coa
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proofreading
-
itraq
- crotonyl-coa
-
methyl-branched
-
poly3-hydroxybutyrate-co-3-hydroxyhexanoate
-
hydratase
- medicine
Reaction
Synonyms
ECHDC1, ethylmalonyl-CoA decarboxylase
ECTree
4.1.1.94 ethylmalonyl-CoA decarboxylaseAdvanced search results
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results (Engineering
Engineering on EC 4.1.1.94 - ethylmalonyl-CoA decarboxylase
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PROTEIN VARIANTS 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
synthesis
improved artificial pathway for the biosynthesis of poly((R)-3-hydroxybutyrate-co-(R)-3-hydroxyhexanoate) with high 3-hydroxyhexanoate composition from fructose in Ralstonia eutropha. Introduction of EchDC1, encoding codon-optimized ethylmalonyl-CoA decarboxylase increases poly((R)-3-hydroxybutyrate-co-(R)-3-hydroxyhexanoate) biosynthesis, probably by converting ethylmalonyl-CoA generated by the reductive carboxylase activity of crotonyl-CoA carboxylase/reductase back into butyryl-CoA
additional information
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expression of siRNA in HEK-293T cells suppresses the enzyme with an about 3fold decrease in ECHDC1 mRNA levels
