4.1.1.94: ethylmalonyl-CoA decarboxylase

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For detailed information about ethylmalonyl-CoA decarboxylase, go to the full flat file.

ECHDC1, ethylmalonyl-CoA decarboxylase

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Results	in table
15	AA Sequence
1	Application
1	Cloned(Commentary)
24	Disease/ Diagnostics
5	General Information
2	Inhibitors
4	kcat/KM [mM/s]
4	KM Value [mM]
4	Localization
1	Molecular Weight [Da]
5	Organism
2	Pathway
3	pH Optimum
2	Protein Variants
2	Purification (Commentary)
1	Reaction
5	Reference
8	Source Tissue
1	Specific Activity [micromol/min/mg]
9	Substrates and Products (Substrate)
1	Subunits
7	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
4	Turnover Number [1/s]

Disease on EC 4.1.1.94 - ethylmalonyl-CoA decarboxylase

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Breast Neoplasms

Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33.

Multi-modal meta-analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor.

The RNF146 and ECHDC1 genes as candidates for inherited breast and ovarian cancer in Jewish Ashkenazi women.

ethylmalonyl-coa decarboxylase deficiency

ECHDC1 knock-out mice accumulate ethyl-branched lipids and excrete abnormal intermediates of branched-chain fatty acid metabolism.

Neoplasms

Multi-modal meta-analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor.

The RNF146 and ECHDC1 genes as candidates for inherited breast and ovarian cancer in Jewish Ashkenazi women.

Ovarian Neoplasms

The RNF146 and ECHDC1 genes as candidates for inherited breast and ovarian cancer in Jewish Ashkenazi women.