4.1.1.45: aminocarboxymuconate-semialdehyde decarboxylase

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For detailed information about aminocarboxymuconate-semialdehyde decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.45

4.1.1.45

quinolinic

3-hydroxyanthranilate

niacin

tryptophan-niacine

nicotinic

kynureninase

3,4-dioxygenase

kynurenine-oxoglutarate

phosphoribosyltransferase

3-monooxygenase

l-tryptophan

pyrazinamide

n1-methylnicotinamide

medicine

qa

l-kynurenine

acid-free

kynurenic

di2-ethylhexylphthalate

quin

tryptophan-nad

excitotoxin

nmn

drug development

Reaction

2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate

Synonyms

2-amino 3-carboxymuconate 6-semialdehyde decarboxylase, 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, 3-(3-oxoprop-2-enyl)-2-aminobut-2-endioate carboxy-lyase, ACMS decarboxylase, ACMSD, ACMSD I, ACMSDase, alpha-amino beta-carboxymuconate epsilon-semialdehyde decarboxylase, alpha-Amino-beta-carboxymuconate-epsilon-semialdehade decarboxylase, alpha-Amino-beta-carboxymuconate-epsilon-semialdehyde beta-decarboxylase, alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, alpha-amino-beta-carboxymuconic-epsilon-semialdehyde decarboxylase, Amino-carboxymuconate-semialdehyde decarboxylase, Decarboxylase, aminocarboxymuconate semialdehyde, hACMSD, NbaD enzyme, Picolinic acid carboxylase, Picolinic acid decarboxylase, picolinic carboxylase, Picolinic decarboxylase

ECTree

4 Lyases

4.1 Carbon-carbon lyases

4.1.1 Carboxy-lyases

4.1.1.45 aminocarboxymuconate-semialdehyde decarboxylase

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Results	in table
2	Activating Compound
1722	AA Sequence
10	Application
1	CAS Registry Number
17	Cloned(Commentary)
6	Crystallization (Commentary)
29	Disease/ Diagnostics
3	Expression
3	General Information
1	IC50 Value
50	Inhibitors
1	Ki Value [mM]
21	KM Value [mM]
25	Metals/Ions
11	Molecular Weight [Da]
31	Natural Substrates/ Products (Substrates)
47	Organism
7	Pathway
33	PDB ID
7	pH Optimum
1	pH Range
2	pH Stability
14	Protein Variants
15	Purification (Commentary)
2	Reaction
2	Reaction Type
46	Reference
24	Source Tissue
17	Specific Activity [micromol/min/mg]
6	Storage Stability
70	Substrates and Products (Substrate)
5	Subunits
75	Synonyms
1	Systematic Name
2	Temperature Stability [°C]
16	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 4.1.1.45 - aminocarboxymuconate-semialdehyde decarboxylase

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37140

Pseudomonas fluorescens

Q83V25

deduced from DNA sequence

38090

deduced from cDNA

38700

Pseudomonas fluorescens

Q83V25

recombinant protein, SDS-PAGE

39000

40000

SDS-PAGE

41000

50000

gel filtration

58000

gel filtration