4.1.1.45: aminocarboxymuconate-semialdehyde decarboxylase

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For detailed information about aminocarboxymuconate-semialdehyde decarboxylase, go to the full flat file.

Reaction

Synonyms

2-amino 3-carboxymuconate 6-semialdehyde decarboxylase, 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, 3-(3-oxoprop-2-enyl)-2-aminobut-2-endioate carboxy-lyase, ACMS decarboxylase, ACMSD, ACMSD I, ACMSDase, alpha-amino beta-carboxymuconate epsilon-semialdehyde decarboxylase, alpha-Amino-beta-carboxymuconate-epsilon-semialdehade decarboxylase, alpha-Amino-beta-carboxymuconate-epsilon-semialdehyde beta-decarboxylase, alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, alpha-amino-beta-carboxymuconic-epsilon-semialdehyde decarboxylase, Amino-carboxymuconate-semialdehyde decarboxylase, Decarboxylase, aminocarboxymuconate semialdehyde, hACMSD, NbaD enzyme, Picolinic acid carboxylase, Picolinic acid decarboxylase, picolinic carboxylase, Picolinic decarboxylase

ECTree

     4 Lyases

         4.1 Carbon-carbon lyases

             4.1.1 Carboxy-lyases

                4.1.1.45 aminocarboxymuconate-semialdehyde decarboxylase

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Results	in table
2	Activating Compound
1722	AA Sequence
10	Application
1	CAS Registry Number
17	Cloned(Commentary)
6	Crystallization (Commentary)
29	Disease/ Diagnostics
3	Expression
3	General Information
1	IC50 Value
50	Inhibitors
1	Ki Value [mM]
21	KM Value [mM]
25	Metals/Ions
11	Molecular Weight [Da]
31	Natural Substrates/ Products (Substrates)
47	Organism
7	Pathway
33	PDB ID
7	pH Optimum
1	pH Range
2	pH Stability
14	Protein Variants
15	Purification (Commentary)
2	Reaction
2	Reaction Type
46	Reference
24	Source Tissue
17	Specific Activity [micromol/min/mg]
6	Storage Stability
70	Substrates and Products (Substrate)
5	Subunits
75	Synonyms
1	Systematic Name
2	Temperature Stability [°C]
16	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 4.1.1.45 - aminocarboxymuconate-semialdehyde decarboxylase

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-20°C, 50 mM potassium phosphate buffer, pH 7.0, 0.14 M KCl, 5 mM 2-mercaptoethanol, 1 mM dithiothreitol, 1 mM EDTA, 20% glycerol, stable for at least 1 month

Sus scrofa

-

4570

-20°C, stable for several months

Felis catus

-

4567, 4568

-78°C, enzyme endures freeze/thaw cycles multiple times without a significant loss of activity

Homo sapiens

Q8TDX5

749250

4°C, 10 mM Tris-HCl, pH 8.0, 0.13 m NaCl, several weeks, remains stable

Homo sapiens

-

679800

4°C, stable for weeks

Homo sapiens

Q8TDX5

749250