3.6.4.B1: kinesin K16

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For detailed information about kinesin K16, go to the full flat file.

Reaction

Synonyms

AtPAKRP1, AtPAKRP1L, GhKCH1, K16MD, KCBP, KIF 14, KIF18A, KIF4, KIF5, KIF5B, KIF5C, KIFC5A, kinesin K-16, kinesin K16, kinesin K16MD, kinesin KIF17b, kinesin kif5c, kinesin superfamily protein 5B, kinesin-1 motor protein, kinesin-like calmodulin-binding protein, KLP-6 kinesin, MS-KIF18A

ECTree

     3 Hydrolases

         3.6 Acting on acid anhydrides

             3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement

                3.6.4.B1 kinesin K16

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Results	in table
5	Activating Compound
2	Application
9	Cloned(Commentary)
3	Crystallization (Commentary)
5	Disease/ Diagnostics
2	Inhibitors
18	Localization
2	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
25	Organism
2	pH Optimum
4	Protein Variants
2	Purification (Commentary)
1	Reaction
25	Reference
14	Source Tissue
2	Specific Activity [micromol/min/mg]
18	Substrates and Products (Substrate)
10	Subunits
23	Synonyms
1	Temperature Optimum [°C]

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Application on EC 3.6.4.B1 - kinesin K16

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APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

analysis

Oryza sativa

-

photoreactiveATP derivative, 2'(3')-O-(4-benzoylbenzoyl)-1,N6-etheno-ATP acts as a cross-linker to detect conformational changes in the kinesin motor domain

687437

medicine

Homo sapiens

-

in muscles of patients with idiopathic inflammatory myopathies, KIF4-positive inflammatory cells are found. In polymyositis and inclusion body myositis, KIF4-positive cells are mainly located around individual muscle fibers, whereas in dermamyositis, KIF4-positive cells are also near blood vessels. KIF4-positive cells are not specific to any immune lineage. In peripheral blood lymphocytes stimulated with mitogens, KIF4 expression is upregulated, and the protein is localized in the cytoplasm associated with lysosome-associated protein 1+ and perforin+ lysosomal vesicles

688535