3.6.4.B1: kinesin K16
This is an abbreviated version!
For detailed information about kinesin K16, go to the full flat file.
Word Map on EC 3.6.4.B1
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3.6.4.B1
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microtubule
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cargo
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testis-specific
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crem
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microtubule-dependent
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plant-specific
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kinesin-related
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phragmoplast
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phosphorylation-independent
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male-specific
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analysis
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medicine
- 3.6.4.B1
- microtubule
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cargo
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testis-specific
- crem
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microtubule-dependent
-
plant-specific
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kinesin-related
- phragmoplast
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phosphorylation-independent
-
male-specific
- analysis
- medicine
Reaction
Synonyms
AtPAKRP1, AtPAKRP1L, GhKCH1, K16MD, KCBP, KIF 14, KIF18A, KIF4, KIF5, KIF5B, KIF5C, KIFC5A, kinesin K-16, kinesin K16, kinesin K16MD, kinesin KIF17b, kinesin kif5c, kinesin superfamily protein 5B, kinesin-1 motor protein, kinesin-like calmodulin-binding protein, KLP-6 kinesin, MS-KIF18A
ECTree
3.6.4.B1 kinesin K16Advanced search results
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results (Substrates Products
Substrates Products on EC 3.6.4.B1 - kinesin K16
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
ATP + H2O
ADP + phosphate
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KLP-6 kinesin is required for male mating behaviors and polycystin localization in Caenorhabditis elegans
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?
ATP + H2O
ADP + phosphate
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highly dynamic expression pattern for kif5c in a variety of developing tissues including neuronal and mesodermal tissues. In young embryos the expression pattern around Hensens node is asymmetric with stronger expression on the right side, implying that kif5c is involved in the formation of the left-right body axis. At later stages, kif5c expression is found in the paraxial, intermediate and somatic mesoderm and in the tail bud. The expression in the paraxial mesoderm occurs first during segmentation and continues in the epithelial somites and the dermomyotome. During neurulation kif5c is expressed in ectodermal and neural-plate cells. In older embryos, the expression is restricted to the dorsal root and cranial ganglia, neural tube and olfactory tract
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?
ATP + H2O
ADP + phosphate
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GhKCH1 may play a role in organizing the actin network in coordination with the cortical microtubule array
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?
ATP + H2O
ADP + phosphate
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interactions between MS-KIF18A, ERalpha and caveolin-1 are involved in the estrogen non-genomic response and the activation of the ERK pathway in MBA-15 cells
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?
ATP + H2O
ADP + phosphate
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KIF17b is involved in the nucleocytoplasmic transport of RNA and of a transcriptional coactivator. A functional interplay between KIF17b and MIWI might be needed for the leading of haploid RNAs in the chromatoid body
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?
additional information
?
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the selection of a large array of cargoes for transport by a restricted number of kinesin motor proteins is mediated by adaptor proteins such as Ran-binding protein 2
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?
additional information
?
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function of Spatial in spermatid differentiation as a cargo of kinesin KIF17b
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?
additional information
?
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role for KIF18A and estrogen receptor alpha in a non-genomic response of MBA-15 cells challenged with 17beta-estrogen
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?
additional information
?
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kinesin-1 preferentially binds to and trafficks on detyrosinated microtubules in vivo, providing a potential bias for the spatial targeting of kinesin-1 based cargo transport
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?
