3.6.1.60: diadenosine hexaphosphate hydrolase (AMP-forming)

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For detailed information about diadenosine hexaphosphate hydrolase (AMP-forming), go to the full flat file.

Reaction

Synonyms

At3g26690, AtNUDT13, DDP1, diphosphoinositol polyphosphate phosphohydrolase, DIPP, hAps1, hAps2, More, NUDT10, NUDT11

ECTree

     3 Hydrolases

         3.6 Acting on acid anhydrides

             3.6.1 In phosphorus-containing anhydrides

                3.6.1.60 diadenosine hexaphosphate hydrolase (AMP-forming)

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Results	in table
2	Activating Compound
15	AA Sequence
1	Application
4	Cloned(Commentary)
26	Disease/ Diagnostics
1	Expression
3	General Information
2	IC50 Value
9	Inhibitors
9	kcat/KM [mM/s]
2	Ki Value [mM]
9	KM Value [mM]
2	Localization
9	Metals/Ions
4	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
9	Organism
13	PDB ID
7	pH Optimum
2	pH Range
3	Protein Variants
2	Purification (Commentary)
7	Reaction
7	Reference
24	Source Tissue
20	Substrates and Products (Substrate)
4	Subunits
11	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
9	Turnover Number [1/s]

Disease

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Disease on EC 3.6.1.60 - diadenosine hexaphosphate hydrolase (AMP-forming)

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Asthma

Suggestive association between variants in IL1RAPL and asthma symptoms in Latin American children.

28120837

Neoplasms

Bioinformatics Analysis Reveals an Association Between Cancer Cell Stemness, Gene Mutations, and the Immune Microenvironment in Stomach Adenocarcinoma.

33362856

Neoplasms

Exploring targets of TET2-mediated methylation reprogramming as potential discriminators of prostate cancer progression.

30917865

Ovarian Neoplasms

Autoantibody biomarkers for the detection of serous ovarian cancer.

28427776

Ovarian Neoplasms

Systematic review: Tumor-associated antigen autoantibodies and ovarian cancer early detection.

28800944

Ovarian Neoplasms

Tumor-associated autoantibodies as early detection markers for ovarian cancer? A prospective evaluation.

29473162

Prostatic Neoplasms

Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis.

22730461

Prostatic Neoplasms

NUDT11 rs5945572 polymorphism and prostate cancer risk: a meta-analysis.

26064238

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