3.5.4.42: N-isopropylammelide isopropylaminohydrolase

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For detailed information about N-isopropylammelide isopropylaminohydrolase, go to the full flat file.

Reaction

Synonyms

amidase, N-isopropylammelide, AtzC, EC 3.5.99.4, IAIA, N-isopropylammelide amidase, N-isopropylammelide isopropylamidohydrolase

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.4 In cyclic amidines

3.5.4.42 N-isopropylammelide isopropylaminohydrolase

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Results	in table
1	Activating Compound
537	AA Sequence
15	Application
1	CAS Registry Number
6	Cloned(Commentary)
1	Crystallization (Commentary)
2	Expression
3	General Information
10	Inhibitors
14	kcat/KM [mM/s]
3	Ki Value [mM]
22	KM Value [mM]
4	Metals/Ions
4	Molecular Weight [Da]
30	Natural Substrates/ Products (Substrates)
50	Organism
6	Pathway
1	PDB ID
16	Protein Variants
2	Purification (Commentary)
1	Reaction
1	Reaction Type
38	Reference
1	Renatured (Commentary)
2	Source Tissue
1	Specific Activity [micromol/min/mg]
53	Substrates and Products (Substrate)
2	Subunits
56	Synonyms
1	Systematic Name
3	Temperature Stability [°C]
14	Turnover Number [1/s]

Reaction

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Reaction on EC 3.5.4.42 - N-isopropylammelide isopropylaminohydrolase

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N-isopropylammelide + H2O = cyanuric acid + isopropylamine

Involved in a pathway by which the herbicide atrazine, 2-chloro-4-(ethylamino)-6-(isopopylamino)-1,3,5-triazine, is degraded in bacteria via N-isopropylammelide, 2,4-dihydroxy-6-(isopropylamino)-1,3,5-triazine