3.5.1.16: acetylornithine deacetylase

This is an abbreviated version!
For detailed information about acetylornithine deacetylase, go to the full flat file.

Reaction

Synonyms

acetylornithinase, AO, AOase, arg-E encoded N-acetyl L-ornithine deacetylase, ArgE, argE-encoded N-acetyl-L-ornithine deacetylase, At4g17830, E. coli AO, enterobacterial AOase, N(alpha)-acetyl-L-ornithine deacetylase, N-acetyl-L-ornithine deacetylase, N-acetylornithinase, N-acetylornithine deacetylase, N2-acetylornithine:N-acetylglutamate acetyltransferase, NAO, NAO deacetylase, NAOD, NAOGAcT

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.1 In linear amides

                3.5.1.16 acetylornithine deacetylase

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Results	in table
2	Activating Compound
9512	AA Sequence
2	Application
1	CAS Registry Number
8	Cloned(Commentary)
2	Expression
9	General Information
22	IC50 Value
37	Inhibitors
1	kcat/KM [mM/s]
1	Ki Value [mM]
24	KM Value [mM]
16	Metals/Ions
16	Molecular Weight [Da]
27	Natural Substrates/ Products (Substrates)
367	Organism
7	Pathway
14	PDB ID
6	pH Optimum
2	pH Range
6	Protein Variants
8	Purification (Commentary)
1	Reaction
1	Reaction Type
38	Reference
1	Renatured (Commentary)
12	Source Tissue
5	Specific Activity [micromol/min/mg]
95	Substrates and Products (Substrate)
9	Subunits
45	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]
8	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 3.5.1.16 - acetylornithine deacetylase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

N-acetyl-DL-methionine + H2O

methionine + acetate

13 entries

N-acetyl-L-ornithine + H2O

acetate + L-ornithine

Escherichia coli

-

-

720166

-

-

?

N-alpha-acetyl-L-ornithine + H2O

?

Escherichia coli

-

-

687815

-

-

?

N-formyl-L-methionine + H2O

L-methionine + formate

3 entries

N2-acety-L-ornithine + H2O

L-ornithine + acetate

15 entries

N2-acetyl-L-ornithine + H2O

acetate + L-ornithine

8 entries

N2-acetyl-L-ornithine + H2O

L-ornithine + acetate

2 entries

Nalpha-acetyl-DL-serine + H2O

DL-serine + acetate

Escherichia coli

-

-

171964

-

-

?

Nalpha-acetyl-L-alanine + H2O

L-alanine + acetate

3 entries

Nalpha-acetyl-L-asparagine + H2O

L-asparagine + acetate

Escherichia coli

-

-

171964

-

-

?

Nalpha-acetyl-L-cysteine + H2O

L-cysteine + acetate

Escherichia coli

-

-

171964

-

-

?

Nalpha-acetyl-L-glutamine + H2O

L-glutamine + acetate

3 entries

Nalpha-acetyl-L-leucine + H2O

L-leucine + acetate

Escherichia coli

-

-

171964

-

-

?

Nalpha-acetyl-L-lysine + H2O

L-lysine + acetate

Escherichia coli

-

-

171964

-

-

?

Nalpha-acetyl-L-methionine + H2O

acetate + L-methionine

Escherichia coli

-

-

171964

-

-

?

Nalpha-acetyl-L-ornithine + H2O

L-ornithine + acetate

14 entries

Nalpha-benzoyl-L-ornithine + H2O

benzoate + ornithine

3 entries

Nalpha-chloroacetylglycine + H2O

glycine + chloroacetate

Escherichia coli

-

-

171964

-

-

?

N-acetyl-DL-methionine + H2O

methionine + acetate

Aerobacter sp.

-

-

171960

-

-

?

N-acetyl-DL-methionine + H2O

methionine + acetate

Erwinia sp.

-

-

171960

-

-

?

N-acetyl-DL-methionine + H2O

methionine + acetate

Escherichia coli

-

-

171960, 171962, 171964

-

-

?

N-acetyl-DL-methionine + H2O

methionine + acetate

Escherichia coli

P23908

-

171961

-

-

?

N-acetyl-DL-methionine + H2O

methionine + acetate

Escherichia coli 160-37

-

-

171960, 171962, 171964

-

-

?

N-acetyl-DL-methionine + H2O

methionine + acetate

Escherichia coli ATCC 9637

-

-

171960, 171962, 171964

-

-

?

N-acetyl-DL-methionine + H2O

methionine + acetate

Escherichia coli B / ATCC 11303

-

-

171960

-

-

?

N-acetyl-DL-methionine + H2O

methionine + acetate

Klebsiella sp.

-

-

171960

-

-

?

N-acetyl-DL-methionine + H2O

methionine + acetate

Proteus sp.

-

-

171960

-

-

?

N-acetyl-DL-methionine + H2O

methionine + acetate

Saccharomyces sp.

-

-

171962

-

-

?

N-acetyl-DL-methionine + H2O

methionine + acetate

Salmonella sp.

-

-

171960

-

-

?

N-acetyl-DL-methionine + H2O

methionine + acetate

Serratia sp.

-

-

171960

-

-

?

N-acetyl-DL-methionine + H2O

methionine + acetate

Shigella sp.

-

-

171960

-

-

?

N-formyl-L-methionine + H2O

L-methionine + formate

Escherichia coli

-

-

171964

-

-

?

N-formyl-L-methionine + H2O

L-methionine + formate

Escherichia coli 160-37

-

-

171964

-

-

?

N-formyl-L-methionine + H2O

L-methionine + formate

Escherichia coli ATCC 9637

-

-

171964

-

-

?

N2-acety-L-ornithine + H2O

L-ornithine + acetate

Aerobacter sp.

-

step in arginine biosynthesis

171960

-

-

?

N2-acety-L-ornithine + H2O

L-ornithine + acetate

Erwinia sp.

-

step in arginine biosynthesis

171960

-

-

?

N2-acety-L-ornithine + H2O

L-ornithine + acetate

Escherichia coli

-

step in arginine biosynthesis

171960, 171962, 171963, 171964

-

-

?

N2-acety-L-ornithine + H2O

L-ornithine + acetate

Escherichia coli

P23908

step in arginine biosynthesis

171961

-

-

?

N2-acety-L-ornithine + H2O

L-ornithine + acetate

Escherichia coli 160-37

-

step in arginine biosynthesis

171960, 171962, 171963

-

-

?

N2-acety-L-ornithine + H2O

L-ornithine + acetate

Escherichia coli ATCC 9637

-

step in arginine biosynthesis

171960, 171962, 171963

-

-

?

N2-acety-L-ornithine + H2O

L-ornithine + acetate

Escherichia coli B / ATCC 11303

-

step in arginine biosynthesis

171960

-

-

?

N2-acety-L-ornithine + H2O

L-ornithine + acetate

Klebsiella sp.

-

step in arginine biosynthesis

171960

-

-

?

N2-acety-L-ornithine + H2O

L-ornithine + acetate

Moritella abyssi

-

-

171963

-

-

?

N2-acety-L-ornithine + H2O

L-ornithine + acetate

Moritella profunda

-

step in arginine biosynthesis

171963

-

-

?

N2-acety-L-ornithine + H2O

L-ornithine + acetate

Proteus sp.

-

step in arginine biosynthesis

171960

-

-

?

N2-acety-L-ornithine + H2O

L-ornithine + acetate

Saccharomyces sp.

-

step in arginine biosynthesis

171962

-

-

?

N2-acety-L-ornithine + H2O

L-ornithine + acetate

Salmonella sp.

-

step in arginine biosynthesis

171960

-

-

?

N2-acety-L-ornithine + H2O

L-ornithine + acetate

Serratia sp.

-

step in arginine biosynthesis

171960

-

-

?

N2-acety-L-ornithine + H2O

L-ornithine + acetate

Shigella sp.

-

step in arginine biosynthesis

171960

-

-

?

N2-acetyl-L-ornithine + H2O

acetate + L-ornithine

Arabidopsis thaliana

Q9C5C4

-

734884, 755033

-

-

?

N2-acetyl-L-ornithine + H2O

acetate + L-ornithine

Arabidopsis thaliana

-

-

755033

-

-

?

N2-acetyl-L-ornithine + H2O

acetate + L-ornithine

Arabidopsis thaliana

Q9C5C4

the enzyme controls ornithine biosynthesis via a linear pathway with downstream effects on polyamine levels. The role of this enzyme is relevant for the reproductive development of Arabidopsis thaliana, probably contributing to ensure the optimal balance between cellular C and N metabolism necessary for flowering and fruit setting

755033

-

-

?

N2-acetyl-L-ornithine + H2O

acetate + L-ornithine

Arabidopsis thaliana Col-0

Q9C5C4

-

734884

-

-

?

N2-acetyl-L-ornithine + H2O

acetate + L-ornithine

Escherichia coli

-

-

733082

-

-

?

N2-acetyl-L-ornithine + H2O

acetate + L-ornithine

Saccharolobus solfataricus

-

-

725629

-

-

?

N2-acetyl-L-ornithine + H2O

acetate + L-ornithine

Saccharolobus solfataricus P1

-

-

725629

-

-

?

N2-acetyl-L-ornithine + H2O

acetate + L-ornithine

Sinorhizobium meliloti

Q92Y75

-

754657

-

-

?

N2-acetyl-L-ornithine + H2O

L-ornithine + acetate

Escherichia coli

-

-

669046

-

-

?

N2-acetyl-L-ornithine + H2O

L-ornithine + acetate

Escherichia coli BL21 (DE3)

-

-

669046

-

-

?

Nalpha-acetyl-L-alanine + H2O

L-alanine + acetate

Escherichia coli

-

-

171964

-

-

?

Nalpha-acetyl-L-alanine + H2O

L-alanine + acetate

Escherichia coli 160-37

-

-

171964

-

-

?

Nalpha-acetyl-L-alanine + H2O

L-alanine + acetate

Escherichia coli ATCC 9637

-

-

171964

-

-

?

Nalpha-acetyl-L-glutamine + H2O

L-glutamine + acetate

Escherichia coli

-

-

171964

-

-

?

Nalpha-acetyl-L-glutamine + H2O

L-glutamine + acetate

Escherichia coli 160-37

-

-

171964

-

-

?

Nalpha-acetyl-L-glutamine + H2O

L-glutamine + acetate

Escherichia coli ATCC 9637

-

-

171964

-

-

?

Nalpha-acetyl-L-ornithine + H2O

L-ornithine + acetate

Aerobacter sp.

-

-

171960

-

-

?

Nalpha-acetyl-L-ornithine + H2O

L-ornithine + acetate

Erwinia sp.

-

-

171960

-

-

?

Nalpha-acetyl-L-ornithine + H2O

L-ornithine + acetate

Escherichia coli

-

-

171960, 171962, 171963, 171964

-

-

?

Nalpha-acetyl-L-ornithine + H2O

L-ornithine + acetate

Escherichia coli

P23908

-

171961

-

-

?

Nalpha-acetyl-L-ornithine + H2O

L-ornithine + acetate

Escherichia coli 160-37

-

-

171960, 171962, 171963, 171964

-

-

?

Nalpha-acetyl-L-ornithine + H2O

L-ornithine + acetate

Escherichia coli ATCC 9637

-

-

171960, 171962, 171963, 171964

-

-

?

Nalpha-acetyl-L-ornithine + H2O

L-ornithine + acetate

Escherichia coli B / ATCC 11303

-

-

171960

-

-

?

Nalpha-acetyl-L-ornithine + H2O

L-ornithine + acetate

Klebsiella sp.

-

-

171960

-

-

?

Nalpha-acetyl-L-ornithine + H2O

L-ornithine + acetate

Moritella profunda

-

-

171963

-

-

?

Nalpha-acetyl-L-ornithine + H2O

L-ornithine + acetate

Proteus sp.

-

-

171960

-

-

?

Nalpha-acetyl-L-ornithine + H2O

L-ornithine + acetate

Saccharomyces sp.

-

-

171962

-

-

?

Nalpha-acetyl-L-ornithine + H2O

L-ornithine + acetate

Salmonella sp.

-

-

171960

-

-

?

Nalpha-acetyl-L-ornithine + H2O

L-ornithine + acetate

Serratia sp.

-

-

171960

-

-

?

Nalpha-acetyl-L-ornithine + H2O

L-ornithine + acetate

Shigella sp.

-

-

171960

-

-

?

Nalpha-benzoyl-L-ornithine + H2O

benzoate + ornithine

Escherichia coli

-

-

171962

-

-

?

Nalpha-benzoyl-L-ornithine + H2O

benzoate + ornithine

Escherichia coli 160-37

-

-

171962

-

-

?

Nalpha-benzoyl-L-ornithine + H2O

benzoate + ornithine

Escherichia coli ATCC 9637

-

-

171962

-

-

?