3.4.24.B26: myroilysin

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For detailed information about myroilysin, go to the full flat file.

Reaction

broad specificity, elastinolytic activity and collagen-swelling ability =

Synonyms

M10.064, More, MPR_2201

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.24 Metalloendopeptidases

                3.4.24.B26 myroilysin

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Results	in table
1	AA Sequence
3	Application
1	Cloned(Commentary)
1	Crystallization (Commentary)
13	Inhibitors
1	KM Value [mM]
3	Metals/Ions
1	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
14	Organism
2	pH Optimum
1	pI Value
1	Posttranslational Modification
1	Purification (Commentary)
1	Reaction
8	Reference
19	Substrates and Products (Substrate)
2	Subunits
5	Synonyms
2	Temperature Optimum [°C]
3	Temperature Stability [°C]

Application

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Application on EC 3.4.24.B26 - myroilysin

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APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

medicine

Myroides profundi

B5B0E6

construction of a nerve regeneration acellular nerve graft with homologous dental pulp stem cells: Xenogeneic acellular nerve graft Is processed by Myroilysin to completely remove cells and myelin sheath, while preserving extracellular matrix microstructure of the natural nerve. The acellular nerve graft can support cell attachment and proliferation and does not stimulate a vigorous host rejection response. 1 cm purebred New Zealand White Rabbits sciatic nerve defects are repaired using this nerve graft construction

754191

synthesis

2 entries

synthesis

Myroides profundi

B5B0E6

optimization of the culture conditions for protease production, best conditions are (w/v) 1% corn powder, 4% wheat bran, 2% bean powder, 0.4% Na2HPO4, 0.03% KH2PO4, 0.1% CaCl2, and artificial seawater, with the initial pH of 8.0 and 1% inoculation amount, 15°C culture temperature. Under the optimized conditions, the protease activity reaches 1137 U/ml, i.e., 174% of that before optimization. The protease activity in small scale fermentations reaches 1546.4 U/ml after parameter optimization

754793

synthesis

Myroides profundi D25

-

optimization of the culture conditions for protease production, best conditions are (w/v) 1% corn powder, 4% wheat bran, 2% bean powder, 0.4% Na2HPO4, 0.03% KH2PO4, 0.1% CaCl2, and artificial seawater, with the initial pH of 8.0 and 1% inoculation amount, 15°C culture temperature. Under the optimized conditions, the protease activity reaches 1137 U/ml, i.e., 174% of that before optimization. The protease activity in small scale fermentations reaches 1546.4 U/ml after parameter optimization

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