3.4.23.48: plasminogen activator Pla

This is an abbreviated version, for detailed information about plasminogen activator Pla, go to the full flat file.

Reaction

Converts human Glu-plasminogen to plasmin by cleaving the Arg560-/-Val peptide bond that is also hydrolysed by the mammalian u-plasminogen activator and t-plasminogen activator. Also cleaves arginyl bonds in other proteins =

Synonyms

beta-Pla, Pla, Pla protease, plasminogen activator Pla, YapE

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.23 Aspartic endopeptidases
                3.4.23.48 plasminogen activator Pla