3.4.23.35: Barrierpepsin
This is an abbreviated version!
For detailed information about Barrierpepsin, go to the full flat file.
Reaction
Selective cleavage of -Leu6-/-Lys- bond in the pheromone alpha-mating factor =
Synonyms
Bar proteinase, Barrier proteinase, Extracellular "barrier" protein, More
ECTree
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Inhibitors
Inhibitors on EC 3.4.23.35 - Barrierpepsin
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no inhibition by EDTA, 6-aminohexanoic acid, PMSF, aprotinin, leupeptin, tosyl-Lys methyl ester, pepstatin A
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additional information
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alpha factor derived peptides Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr, Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr, His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln, Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln, Trp-Leu-Gln-Leu-Lys-Pro-Gly; the reduced and alkylated B-chain of platelet-derived growth factor, synthetic peptides Lys-Pro-Ile-Glu-Phe-(4-nitro)Phe-Arg-Leu, Ala-Pro-Ala-Lys-Phe-(4-nitro)Phe-Arg-Leu, Arg-Phe-Leu-Glu-(4-nitro)Phe-Lys-Pro-Gly-Gln-Pro, Lys-Pro-Glu-Ile-(4-nitro)Phe-Lys-Ser-Glu-Lys-Ile; Trp-Leu-Gln-Leu-Lys-Pro
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additional information
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Leu-Gln-Leu-Lys, Leu-Gln-Leu-Lys-Pro, Trp-Leu-Gln-Leu, His-Trp-Leu-Gln-Leu, Trp-Leu-Gln-Leu-Lys, Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro, Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-lactone, Saccharomyces kluyveri alpha factor, tosyl-L-Lys chloromethylketone, 1,2-epoxy-3-(4-nitrophenoxy)propane, diazoacetyl-DL-norleucine ester, pepstatin; Trp-Leu-Gln-Leu-Lys-Pro
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additional information
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no inhibition by pepstatin A, EDTA, alpha-amincaproic acid, and several serine proteinase inhibitors, e.g. tosyl arginyl methyl ester
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