3.4.21.102: C-terminal processing peptidase

This is an abbreviated version, for detailed information about C-terminal processing peptidase, go to the full flat file.

Reaction

the enzyme shows specific recognition of a C-terminal tripeptide, Xaa-Yaa-Zaa, in which Xaa is preferably Ala or Leu, Yaa is preferably Ala or Tyr, and Zaa is preferably Ala, but then cleaves at a variable distance from the C-terminus. A typical cleavage is -Ala-Ala-/-Arg-Ala-Ala-Lys-Glu-Asn-Tyr-Ala-Leu-Ala-Ala. In the plant chloroplast, the enzyme removes the C-terminal extension of the D1 polypeptide of photosystem II =

Synonyms

At4g17740, C-terminal processing peptidase, C-terminal processing protease, C-terminal protease, carboxy terminal-processing proteinase, carboxyl terminal processing protease of D1 protein, carboxyl-terminal processing protease, carboxyl-terminal protease, carboxyl-terminal-processing peptidase 2, carboxyterminal processing protease, carboxyterminal processing protease of D1 protein, chloroplast processing enzyme, chloroplast protein precursor processing proteinase, CPE, CtpA, CtpA gene product, CtpB, D1 preprotein-processing proteinase, D1 protein-processing enzyme, D1P, More, PA5734, photosystem D1 protein precursor carboxyl-terminal processing protease, photosystem II D1 C-terminal processing protease, photosystem II D1 protein, photosystem II D1 protein processing proteinase, photosystem II protein D1, photosystem II protein D1 2, PrC, Prc protease, PRC protein, processing peptidase, protease Re, proteinase CtpA, proteinase, chloroplast protein precursor-processing, PsbA4, PXO_04290, SPP, stromal processing peptidase, tail-specific protease, thylakoid protein precursor processing peptidase, Tsp protease

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.102 C-terminal processing peptidase