3.4.14.12: Xaa-Xaa-Pro tripeptidyl-peptidase
This is an abbreviated version!
For detailed information about Xaa-Xaa-Pro tripeptidyl-peptidase, go to the full flat file.
Reaction
Hydrolysis of Xaa-Xaa-Pro-/-Yaa- releasing the N-terminal tripeptide of a peptide with Pro as the third residue (position P1) and where Yaa is not proline
=
Synonyms
prolyl tripeptidyl aminopeptidase, prolyl tripeptidyl peptidase, prolyltripeptidyl aminopeptidase, PTP, PTP39, PtpA
ECTree
Temperature Optimum
Temperature Optimum on EC 3.4.14.12 - Xaa-Xaa-Pro tripeptidyl-peptidase
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25
-
pH 7.6, 0.2 M HEPES, stable for at least 12 h
50
-
significant decrease in activity above
37
-
pH 7.6, 0.2 M HEPES, stable for at least 12 h
42
-
42
activity assay, Ala-Phe-Pro-beta-naphthylamide is used as a substrate